| Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. Smith W.W., Norton D.D., Gorospe M., Jiang H., Nemoto S., Holbrook N.J., Finkel T., Kusiak J.W.
J. Cell Biol. 169:331-339(2005) · UniProtKB (1) · Mapped (18) |
| Expression of the pro-apoptotic gene gadd153/chop is elevated in liver with aging and sensitizes cells to oxidant injury. Ikeyama S., Wang X.T., Li J., Podlutsky A., Martindale J.L., Kokkonen G., van Huizen R., Gorospe M., Holbrook N.J.
J. Biol. Chem. 278:16726-16731(2003) · Mapped (3) |
| P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling. van Huizen R., Martindale J.L., Gorospe M., Holbrook N.J.
J. Biol. Chem. 278:15558-15564(2003) · UniProtKB (1) · Mapped (4) |
| Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations. Milhavet O., Martindale J.L., Camandola S., Chan S.L., Gary D.S., Cheng A., Holbrook N.J., Mattson M.P.
J. Neurochem. 83:673-681(2002) · Mapped (3) |
| Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. McCullough K.D., Martindale J.L., Klotz L.O., Aw T.Y., Holbrook N.J.
Mol. Cell. Biol. 21:1249-1259(2001) · Mapped (3) |
| p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system. Gorospe M., Wang X., Holbrook N.J.
Mol. Cell. Biol. 18:1400-1407(1998) · Mapped (14) |
| p27Kip1 overexpression causes apoptotic death of mammalian cells. Wang X., Gorospe M., Huang Y., Holbrook N.J.
Oncogene 15:2991-2997(1997) · Mapped (4) |
| Induction of mitogen-activated protein kinase phosphatase-1 during acute hypertension. Xu Q., Fawcett T.W., Gorospe M., Guyton K.Z., Liu Y., Holbrook N.J.
Hypertension 30:106-111(1997) · Mapped (2) |
| Induction of GADD153, a CCAAT/enhancer-binding protein (C/EBP)-related gene, during the acute phase response in rats. Evidence for the involvement of C/EBPs in regulating its expression. Sylvester S.L., ap Rhys C.M., Luethy-Martindale J.D., Holbrook N.J.
J. Biol. Chem. 269:20119-20125(1994) · Mapped (3) |
| T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells. Holbrook N.J., Smith K.A., Fornace A.J. Jr., Comeau C.M., Wiskocil R.L., Crabtree G.R.
Proc. Natl. Acad. Sci. U.S.A. 81:1634-1638(1984) · UniProtKB (1) |
| DNA sequence of the 5' flanking region of the human interleukin 2 gene: homologies with adult T-cell leukemia virus. Holbrook N.J., Lieber M., Crabtree G.R.
Nucleic Acids Res. 12:5005-5013(1984) · UniProtKB (1) |
| A viral long terminal repeat in the interleukin 2 gene of a cell line that constitutively produces interleukin 2. Chen S.J., Holbrook N.J., Mitchell K.F., Vallone C.A., Greengard J.S., Crabtree G.R., Lin Y.
Proc. Natl. Acad. Sci. U.S.A. 82:7284-7288(1985) · UniProtKB (1) |
| Nucleotide sequence of the gamma chain gene of rat fibrinogen: conserved intronic sequences. Morgan J.G., Holbrook N.J., Crabtree G.R.
Nucleic Acids Res. 15:2774-2776(1987) · UniProtKB (1) |
| Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells. Siebenlist U., Durand D.B., Bressler P., Holbrook N.J., Norris C.A., Kamoun M., Kant J.A., Crabtree G.R.
Mol. Cell. Biol. 6:3042-3049(1986) · UniProtKB (1) |
| Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I. Cross S.L., Feinberg M.B., Wolf J.B., Holbrook N.J., Wong-Stall F., Leonard W.J.
Cell 49:47-56(1987) · UniProtKB (1) |
| Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Fornace A.J. Jr., Nebert D.W., Hollander M.C., Luethy J.D., Papathanasiou M., Fargnoli J., Holbrook N.J.
Mol. Cell. Biol. 9:4196-4203(1989) · UniProtKB (1) |
| Isolation, characterization and chromosomal localization of the human GADD153 gene. Park J.S., Luethy J.D., Wang M.G., Fargnoli J., Fornace A.J. Jr., McBride O.W., Holbrook N.J.
Gene 116:259-267(1992) · UniProtKB (1) |
