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Perturbation of vacuolar maturation promotes listeriolysin O-independent vacuolar escape during Listeria monocytogenes infection of human cells.

Burrack L.S., Harper J.W., Higgins D.E.

Cell. Microbiol. 11:1382-1398(2009) · Mapped (4)

Recognition of AT-rich DNA binding sites by the MogR repressor.

Shen A., Higgins D.E., Panne D.

Structure 17:769-777(2009) · Mapped (1)

Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation.

Kim W.Y., Gonsiorek E.A., Barnhart C., Davare M.A., Engebose A.J., Lauridsen H., Bruun D., Lesiak A., Wayman G., Bucelli R. et al.

J. Neurochem. 108:1057-1071(2009) · Mapped (1)

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.

Kaser A., Lee A.H., Franke A., Glickman J.N., Zeissig S., Tilg H., Nieuwenhuis E.E., Higgins D.E., Schreiber S., Glimcher L.H. et al.

Cell 134:743-756(2008) · Mapped (2)

Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.

Kimura K., Iwano M., Higgins D.F., Yamaguchi Y., Nakatani K., Harada K., Kubo A., Akai Y., Rankin E.B., Neilson E.G. et al.

Am. J. Physiol. Renal Physiol. 295:F1023-9(2008) · Mapped (5)

Altered cytoplasmic-to-nuclear ratio of survivin is a prognostic indicator in breast cancer.

Brennan D.J., Rexhepaj E., O'Brien S.L., McSherry E., O'Connor D.P., Fagan A., Culhane A.C., Higgins D.G., Jirstrom K., Millikan R.C. et al.

Clin. Cancer Res. 14:2681-2689(2008) · Mapped (10)

Genetic association between alpha-synuclein and idiopathic Parkinson's disease.

Kay D.M., Factor S.A., Samii A., Higgins D.S., Griffith A., Roberts J.W., Leis B.C., Nutt J.G., Montimurro J.S., Keefe R.G. et al.

Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B:1222-1230(2008) · Mapped (3)

Relative levels of M-CSF and GM-CSF influence the specific generation of macrophage populations during infection with Mycobacterium tuberculosis.

Higgins D.M., Sanchez-Campillo J., Rosas-Taraco A.G., Higgins J.R., Lee E.J., Orme I.M., Gonzalez-Juarrero M.

J. Immunol. 180:4892-4900(2008) · Mapped (6)

Inhibition of ROCK activity allows InlF-mediated invasion and increased virulence of Listeria monocytogenes.

Kirchner M., Higgins D.E.

Mol. Microbiol. 68:749-767(2008) · Mapped (6)

Level of HER-2/neu protein expression in breast cancer may affect the development of endogenous HER-2/neu-specific immunity.

Goodell V., Waisman J., Salazar L.G., de la Rosa C., Link J., Coveler A.L., Childs J.S., Fintak P.A., Higgins D.M., Disis M.L.

Mol. Cancer Ther. 7:449-454(2008) · Mapped (8)

Exploring gene-environment interactions in Parkinson's disease.

McCulloch C.C., Kay D.M., Factor S.A., Samii A., Nutt J.G., Higgins D.S., Griffith A., Roberts J.W., Leis B.C., Montimurro J.S. et al.

Hum. Genet. 123:257-265(2008) · Mapped (13)

Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease.

Hutter C.M., Samii A., Factor S.A., Nutt J.G., Higgins D.S., Bird T.D., Griffith A., Roberts J.W., Leis B.C., Montimurro J.S. et al.

Eur. J. Neurol. 15:134-139(2008) · Mapped (4)

Statins decrease expression of the proinflammatory neuropeptides calcitonin gene-related peptide and substance P in sensory neurons.

Bucelli R.C., Gonsiorek E.A., Kim W.Y., Bruun D., Rabin R.A., Higgins D., Lein P.J.

J. Pharmacol. Exp. Ther. 324:1172-1180(2008) · Mapped (1)

Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.

Gramolini A.O., Kislinger T., Alikhani-Koopaei R., Fong V., Thompson N.J., Isserlin R., Sharma P., Oudit G.Y., Trivieri M.G., Fagan A. et al.

Mol. Cell Proteomics 7:519-533(2008) · Mapped (1)

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.

Higgins D.F., Kimura K., Bernhardt W.M., Shrimanker N., Akai Y., Hohenstein B., Saito Y., Johnson R.S., Kretzler M., Cohen C.D. et al.

J. Clin. Invest. 117:3810-3820(2007) · Mapped (12)

The major Vibrio cholerae autoinducer and its role in virulence factor production.

Higgins D.A., Pomianek M.E., Kraml C.M., Taylor R.K., Semmelhack M.F., Bassler B.L.

Nature 450:883-886(2007) · UniProtKB (2)

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy.

Walsh D.W., Roxburgh S.A., McGettigan P., Berthier C.C., Higgins D.G., Kretzler M., Cohen C.D., Mezzano S., Brazil D.P., Martin F.

Biochim. Biophys. Acta 1782:10-21(2008) · Mapped (7)

Association analysis of MAPT H1 haplotype and subhaplotypes in Parkinson's disease.

Zabetian C.P., Hutter C.M., Factor S.A., Nutt J.G., Higgins D.S., Griffith A., Roberts J.W., Leis B.C., Kay D.M., Yearout D. et al.

Ann. Neurol. 62:137-144(2007) · Mapped (5)

CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer.

O'Brien S.L., Fagan A., Fox E.J., Millikan R.C., Culhane A.C., Brennan D.J., McCann A.H., Hegarty S., Moyna S., Duffy M.J. et al.

Int. J. Cancer 120:1434-1443(2007) · Mapped (2)

Two alphaherpesvirus latency-associated gene products influence calcitonin gene-related peptide levels in rat trigeminal neurons.

Hamza M.A., Higgins D.M., Ruyechan W.T.

Neurobiol. Dis. 25:553-560(2007) · Mapped (3)

Validity and utility of a LRRK2 G2019S mutation test for the diagnosis of Parkinson's disease.

Kay D.M., Bird T.D., Zabetian C.P., Factor S.A., Samii A., Higgins D.S., Nutt J., Roberts J.W., Griffith A., Leis B.C. et al.

Genet. Test. 10:221-227(2006) · Mapped (4)

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.

Yoshida M., Kobayashi K., Kuo T.T., Bry L., Glickman J.N., Claypool S.M., Kaser A., Nagaishi T., Higgins D.E., Mizoguchi E. et al.

J. Clin. Invest. 116:2142-2151(2006) · Mapped (1)

The MogR transcriptional repressor regulates nonhierarchal expression of flagellar motility genes and virulence in Listeria monocytogenes.

Shen A., Higgins D.E.

PLoS Pathog. 2:282-295(2006) · UniProtKB (1)

Multireplicon genome architecture of Lactobacillus salivarius.

Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P., Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K. et al.

Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006) · UniProtKB (1,998)

Isolation and characterization of the RAD3 gene of Saccharomyces cerevisiae and inviability of rad3 deletion mutants.

Higgins D.R., Prakash S., Reynolds P., Polakowska R., Weber S., Prakash L.

Proc. Natl. Acad. Sci. U.S.A. 80:5680-5684(1983) · Mapped (1)

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