| A laminin-2, dystroglycan, utrophin axis is required for compartmentalization and elongation of myelin segments. Court F.A., Hewitt J.E., Davies K., Patton B.L., Uncini A., Wrabetz L., Feltri M.L.
J. Neurosci. 29:3908-3919(2009) · Mapped (30) |
| Genes required for functional glycosylation of dystroglycan are conserved in zebrafish. Moore C.J., Goh H.T., Hewitt J.E.
Genomics 92:159-167(2008) · UniProtKB (5) · Mapped (24) |
| Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy. Clapp J., Mitchell L.M., Bolland D.J., Fantes J., Corcoran A.E., Scotting P.J., Armour J.A., Hewitt J.E.
Am. J. Hum. Genet. 81:264-279(2007) · UniProtKB (12) · Mapped (13) |
| Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies. Grewal P.K., McLaughlan J.M., Moore C.J., Browning C.A., Hewitt J.E.
Glycobiology 15:912-923(2005) · UniProtKB (8) · Mapped (4) |
| FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients. Rijkers T., Deidda G., van Koningsbruggen S., van Geel M., Lemmers R.J.L.F., van Deutekom J.C.T., Figlewicz D., Hewitt J.E., Padberg G.W., Frants R.R. et al.
J. Med. Genet. 41:826-836(2004) · UniProtKB (3) |
| Glycosylation defects: a new mechanism for muscular dystrophy? Grewal P.K., Hewitt J.E.
Hum. Mol. Genet. 12 Spec No 2:R259-64(2003) · Mapped (3) |
| SF4 and SFRS14, two related putative splicing factors on human chromosome 19p13.11. Sampson N.D., Hewitt J.E.
Gene 305:91-100(2003) · UniProtKB (4) · Mapped (6) |
| Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy. Grewal P.K., Hewitt J.E.
Biochim. Biophys. Acta 1573:216-224(2002) · Mapped (11) |
| Skeletal, cardiac and tongue muscle pathology, defective retinal transmission, and neuronal migration defects in the Large(myd) mouse defines a natural model for glycosylation-deficient muscle - eye - brain disorders. Holzfeind P.J., Grewal P.K., Reitsamer H.A., Kechvar J., Lassmann H., Hoeger H., Hewitt J.E., Bittner R.E.
Hum. Mol. Genet. 11:2673-2687(2002) · Mapped (5) |
| Identification of the autoantigen SART-1 as a candidate gene for the development of atopy. Wheatley A.P., Bolland D.J., Hewitt J.E., Dewar J.C., Hall I.P.
Hum. Mol. Genet. 11:2143-2146(2002) · Mapped (4) |
| Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin. van Geel M., Dickson M.C., Beck A.F., Bolland D.J., Frants R.R., van der Maarel S.M., de Jong P.J., Hewitt J.E.
Genomics 79:210-217(2002) · UniProtKB (2) |
| Intron loss in the SART1 genes of Fugu rubripes and Tetraodon nigroviridis. Bolland D.J., Hewitt J.E.
Gene 271:43-49(2001) · UniProtKB (12) |
| Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse. Grewal P.K., Holzfeind P.J., Bittner R.E., Hewitt J.E.
Nat. Genet. 28:151-154(2001) · UniProtKB (1) · Mapped (11) |
| The murine urea transporter genes Slc14a1 and Slc14a2 occur in tandem on chromosome 18. Fenton R.A., Hewitt J.E., Howorth A., Cottingham C.A., Smith C.P.
Cytogenet. Cell Genet. 87:95-96(1999) · Mapped (6) |
| Cloning of the murine unconventional myosin gene Myo9b and identification of alternative splicing. Grewal P.K., Jones A.-M., Maconochie M., Lemmers R.J.F., Frants R.R., Hewitt J.E.
Gene 240:389-398(1999) · UniProtKB (2) · Mapped (7) |
| The FSHD region on human chromosome 4q35 contains potential coding regions among pseudogenes and a high density of repeat elements. van Geel M., Heather L.J., Lyle R., Hewitt J.E., Frants R.R., de Jong P.J.
Genomics 61:55-65(1999) · UniProtKB (1) |
| Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element. Gabrieels J., Beckers M.-C., Ding H., De Vriese A., Plaisance S., van der Maarel S.M., Padberg G.W., Frants R.R., Hewitt J.E., Collen D. et al.
Gene 236:25-32(1999) · UniProtKB (7) |
| FRG1, a gene in the FSH muscular dystrophy region on human chromosome 4q35, is highly conserved in vertebrates and invertebrates. Grewal P.K., Todd L.C., van der Maarel S., Frants R.R., Hewitt J.E.
Gene 216:13-19(1998) · UniProtKB (7) · Mapped (2) |
| High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint. Grewal P.K., Bolland D.J., Todd L.C., Hewitt J.E.
Mamm. Genome 9:603-607(1998) · UniProtKB (1) · Mapped (45) |
| The mouse homolog of FRG1, a candidate gene for FSHD, maps proximal to the myodystrophy mutation on chromosome 8. Grewal P.K., van Deutekom J.C., Mills K.A., Lemmers R.J., Mathews K.D., Frants R.R., Hewitt J.E.
Mamm. Genome 8:394-398(1997) · UniProtKB (5) · Mapped (17) |
| Fath, the murine homolog of the Drosophila fat tumor suppressor gene, maps to chromosome 8. Grewal P.K., Hewitt J.E.
Mamm. Genome 8:383-384(1997) · Mapped (12) |
| Identification of the first gene (FRG1) from the FSHD region on human chromosome 4q35. van Deutekom J.C.T., Lemmers R.J.L.F., Grewal P.K., van Geel M., Romberg S., Dauwerse H.G., Wright T.J., Padberg G.W., Hofker M.H., Hewitt J.E. et al.
Hum. Mol. Genet. 5:581-590(1996) · UniProtKB (1) |
| Analysis of the tandem repeat locus D4Z4 associated with facioscapulohumeral muscular dystrophy. Hewitt J.E., Lyle R., Clark L.N., Valleley E.M., Wright T.J., Wijmenga C., van Deutekom J.C., Francis F., Sharpe P.T., Hofker M.
Hum. Mol. Genet. 3:1287-1295(1994) · UniProtKB (2) |
| An alternatively spliced transcript, p65 delta 2, of the gene encoding the p65 subunit of the transcription factor NF-kappa B. Lyle R., Valleley E.M., Sharpe P.T., Hewitt J.E.
Gene 138:265-266(1994) · UniProtKB (1) |
| Fine mapping of the FSHD gene region orientates the rearranged fragment detected by the probe p13E-11. Wright T.J., Wijmenga C., Clark L.N., Frants R.R., Williamson R., Hewitt J.E.
Hum. Mol. Genet. 2:1673-1678(1993) · UniProtKB (1) |
