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1 - 25 of 72 results for author:"Helin K." in Literature citations

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Tet2 facilitates the derepression of myeloid target genes during CEBPalpha-induced transdifferentiation of pre-B cells.

Kallin E.M., Rodriguez-Ubreva J., Christensen J., Cimmino L., Aifantis I., Helin K., Ballestar E., Graf T.

Mol. Cell 48:266-276(2012) · Mapped (3)

Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins.

Boulay G., Dubuissez M., Van Rechem C., Forget A., Helin K., Ayrault O., Leprince D.

J. Biol. Chem. 287:10509-10524(2012) · Mapped (8)

Jarid1b targets genes regulating development and is involved in neural differentiation.

Schmitz S.U., Albert M., Malatesta M., Morey L., Johansen J.V., Bak M., Tommerup N., Abarrategui I., Helin K.

EMBO J. 30:4586-4600(2011) · Mapped (5)

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.

Williams K., Christensen J., Pedersen M.T., Johansen J.V., Cloos P.A., Rappsilber J., Helin K.

Nature 473:343-348(2011) · UniProtKB (4) · Mapped (8)

SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation.

Jorgensen S., Eskildsen M., Fugger K., Hansen L., Larsen M.S., Kousholt A.N., Syljuasen R.G., Trelle M.B., Jensen O.N., Helin K. et al.

J. Cell Biol. 192:43-54(2011) · Mapped (13)

Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation.

Gehani S.S., Agrawal-Singh S., Dietrich N., Christophersen N.S., Helin K., Hansen K.

Mol. Cell 39:886-900(2010) · Mapped (8)

A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.

Negishi M., Saraya A., Mochizuki S., Helin K., Koseki H., Iwama A.

PLoS ONE 5:e12373-e12373(2010) · Mapped (13)

A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation.

Kleine-Kohlbrecher D., Christensen J., Vandamme J., Abarrategui I., Bak M., Tommerup N., Shi X., Gozani O., Rappsilber J., Salcini A.E. et al.

Mol. Cell 38:165-178(2010) · UniProtKB (3) · Mapped (6)

Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36.

Jung H.R., Pasini D., Helin K., Jensen O.N.

Mol. Cell Proteomics 9:838-850(2010) · Mapped (5)

NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.

Soerensen C.S., Melixetian M., Klein D.K., Helin K.

Cell Cycle 9:450-455(2010) · UniProtKB (3) · Mapped (7)

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

Pasini D., Cloos P.A., Walfridsson J., Olsson L., Bukowski J.P., Johansen J.V., Bak M., Tommerup N., Rappsilber J., Helin K.

Nature 464:306-310(2010) · UniProtKB (2) · Mapped (10)

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

Ciro M., Prosperini E., Quarto M., Grazini U., Walfridsson J., McBlane F., Nucifero P., Pacchiana G., Capra M., Christensen J. et al.

Cancer Res. 69:8491-8498(2009) · Mapped (1)

NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint.

Melixetian M., Klein D.K., Soerensen C.S., Helin K.

Nat. Cell Biol. 11:1247-1253(2009) · UniProtKB (3) · Mapped (3)

The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1.

Jenal M., Trinh E., Britschgi C., Britschgi A., Roh V., Vorburger S.A., Tobler A., Leprince D., Fey M.F., Helin K. et al.

Mol. Cancer Res. 7:916-922(2009) · Mapped (7)

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence.

Agger K., Cloos P.A., Rudkjaer L., Williams K., Andersen G., Christensen J., Helin K.

Genes Dev. 23:1171-1176(2009) · Mapped (10)

Isolation and characterization of DUSP11, a novel p53 target gene.

Caprara G., Zamponi R., Melixetian M., Helin K.

J. Cell. Mol. Med. 13:2158-2170(2009) · Mapped (1)

Human CDT1 associates with CDC7 and recruits CDC45 to chromatin during S phase.

Ballabeni A., Zamponi R., Caprara G., Melixetian M., Bossi S., Masiero L., Helin K.

J. Biol. Chem. 284:3028-3036(2009) · Mapped (11)

Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.

Lindroth A.M., Park Y.J., McLean C.M., Dokshin G.A., Persson J.M., Herman H., Pasini D., Miro X., Donohoe M.E., Lee J.T. et al.

PLoS Genet. 4:e1000145-e1000145(2008) · Mapped (5)

The polycomb repressive complex 2 is a potential target of SUMO modifications.

Riising E.M., Boggio R., Chiocca S., Helin K., Pasini D.

PLoS ONE 3:E2704-E2704(2008) · UniProtKB (2) · Mapped (9)

DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function.

Britschgi A., Trinh E., Rizzi M., Jenal M., Ress A., Tobler A., Fey M.F., Helin K., Tschan M.P.

Oncogene 27:5706-5716(2008) · Mapped (5)

Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.

Herranz N., Pasini D., Diaz V.M., Franci C., Gutierrez A., Dave N., Escriva M., Hernandez-Munoz I., Di Croce L., Helin K. et al.

Mol. Cell. Biol. 28:4772-4781(2008) · Mapped (11)

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D., Hansen K.H., Christensen J., Agger K., Cloos P.A., Helin K.

Genes Dev. 22:1345-1355(2008) · Mapped (7)

A role for the transcription factor HEY1 in glioblastoma.

Hulleman E., Quarto M., Vernell R., Masserdotti G., Colli E., Kros J.M., Levi D., Gaetani P., Tunici P., Finocchiaro G. et al.

J. Cell. Mol. Med. 13:136-146(2009) · Mapped (3)

The histone methyltransferase SET8 is required for S-phase progression.

Jorgensen S., Elvers I., Trelle M.B., Menzel T., Eskildsen M., Jensen O.N., Helleday T., Helin K., Sorensen C.S.

J. Cell Biol. 179:1337-1345(2007) · Mapped (2)

Association of kallikrein gene polymorphisms with intracranial aneurysms.

Weinsheimer S., Goddard K.A., Parrado A.R., Lu Q., Sinha M., Lebedeva E.R., Ronkainen A., Niemela M., Khusnutdinova E.K., Khusainova R.I. et al.

Stroke 38:2670-2676(2007) · Mapped (4)

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