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NRAS and BRAF mutations in cutaneous melanoma and the association with MC1R genotype: findings from Spanish and Austrian populations.

Hacker E., Nagore E., Cerroni L., Woods S.L., Hayward N.K., Chapman B., Montgomery G.W., Soyer H.P., Whiteman D.C.

J. Invest. Dermatol. 133:1027-1033(2013) · Mapped (8)

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A., McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M. et al.

Nat. Genet. 44:1006-1014(2012) · Mapped (1)

Menin and p53 have non-synergistic effects on tumorigenesis in mice.

Loffler K.A., Mould A.W., Waring P.M., Hayward N.K., Kay G.F.

BMC Cancer 12:252-252(2012) · Mapped (19)

MS4A1 dysregulation in asbestos-related lung squamous cell carcinoma is due to CD20 stromal lymphocyte expression.

Wright C.M., Savarimuthu Francis S.M., Tan M.E., Martins M.U., Winterford C., Davidson M.R., Duhig E.E., Clarke B.E., Hayward N.K., Yang I.A. et al.

PLoS ONE 7:e34943-e34943(2012) · Mapped (3)

Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma.

Sriram K.B., Larsen J.E., Savarimuthu Francis S.M., Wright C.M., Clarke B.E., Duhig E.E., Brown K.M., Hayward N.K., Yang I.A., Bowman R.V. et al.

PLoS ONE 7:e30398-e30398(2012) · Mapped (2)

Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene.

Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S., O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D., O'Rourke M. et al.

Genes Chromosomes Cancer 51:452-461(2012) · Mapped (7)

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.

Stark M.S., Woods S.L., Gartside M.G., Bonazzi V.F., Dutton-Regester K., Aoude L.G., Chow D., Sereduk C., Niemi N.M., Tang N. et al.

Nat. Genet. 44:165-169(2012) · Mapped (10)

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.

Yokoyama S., Woods S.L., Boyle G.M., Aoude L.G., MacGregor S., Zismann V., Gartside M., Cust A.E., Haq R., Harland M. et al.

Nature 480:99-103(2011) · UniProtKB (1) · Mapped (4)

Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.

Bonazzi V.F., Nancarrow D.J., Stark M.S., Moser R.J., Boyle G.M., Aoude L.G., Schmidt C., Hayward N.K.

PLoS ONE 6:e26121-e26121(2011) · Mapped (16)

Polymorphisms in nevus-associated genes MTAP, PLA2G6, and IRF4 and the risk of invasive cutaneous melanoma.

Kvaskoff M., Whiteman D.C., Zhao Z.Z., Montgomery G.W., Martin N.G., Hayward N.K., Duffy D.L.

Twin Res Hum Genet 14:422-432(2011) · Mapped (8)

Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor.

Boyle G.M., Woods S.L., Bonazzi V.F., Stark M.S., Hacker E., Aoude L.G., Dutton-Regester K., Cook A.L., Sturm R.A., Hayward N.K.

Pigment Cell Melanoma Res 24:525-537(2011) · Mapped (2)

Melanocortin 1 receptor and risk of cutaneous melanoma: a meta-analysis and estimates of population burden.

Williams P.F., Olsen C.M., Hayward N.K., Whiteman D.C.

Int. J. Cancer 129:1730-1740(2011) · Mapped (21)

Association of MC1R variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study.

Melanoma Genetics Consortium
Demenais F., Mohamdi H., Chaudru V., Goldstein A.M., Newton Bishop J.A., Bishop D.T., Kanetsky P.A., Hayward N.K., Gillanders E., Elder D.E. et al.

J. Natl. Cancer Inst. 102:1568-1583(2010) · Mapped (21)

ADAM28: a potential oncogene involved in asbestos-related lung adenocarcinomas.

Wright C.M., Larsen J.E., Hayward N.K., Martins M.U., Tan M.E., Davidson M.R., Savarimuthu S.M., McLachlan R.E., Passmore L.H., Windsor M.N. et al.

Genes Chromosomes Cancer 49:688-698(2010) · Mapped (3)

Alterations in gene expression in MEN1-associated insulinoma development.

Serewko-Auret M.M., Mould A.W., Loffler K.A., Duncan R., Kay G.F., Hayward N.K.

Pancreas 39:1140-1146(2010) · Mapped (10)

KCNN4 gene variant is associated with ileal Crohn's Disease in the Australian and New Zealand population.

Simms L.A., Doecke J.D., Roberts R.L., Fowler E.V., Zhao Z.Z., McGuckin M.A., Huang N., Hayward N.K., Webb P.M., Whiteman D.C. et al.

Am. J. Gastroenterol. 105:2209-2217(2010) · Mapped (4)

Association of Helicobacter pylori infection with reduced risk for esophageal cancer is independent of environmental and genetic modifiers.

Whiteman D.C., Parmar P., Fahey P., Moore S.P., Stark M., Zhao Z.Z., Montgomery G.W., Green A.C., Hayward N.K., Webb P.M. et al.

Gastroenterology 139:73-83; quiz 2010:e11-2(2010) · Mapped (9)

Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.

Tonks I.D., Mould A.W., Schroder W.A., Cotterill A., Hayward N.K., Walker G.J., Kay G.F.

Neoplasia 12:235-243(2010) · Mapped (18)

Coexisting NRAS and BRAF mutations in primary familial melanomas with specific CDKN2A germline alterations.

Jovanovic B., Egyhazi S., Eskandarpour M., Ghiorzo P., Palmer J.M., Bianchi Scarra G., Hayward N.K., Hansson J.

J. Invest. Dermatol. 130:618-620(2010) · Mapped (8)

Expression profiling identifies genes involved in emphysema severity.

Francis S.M., Larsen J.E., Pavey S.J., Bowman R.V., Hayward N.K., Fong K.M., Yang I.A.

Respir. Res. 10:81-81(2009) · Mapped (2)

Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.

Duffy D.L., Zhao Z.Z., Sturm R.A., Hayward N.K., Martin N.G., Montgomery G.W.

J. Invest. Dermatol. 130:520-528(2010) · Mapped (36)

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.

Falchi M., Bataille V., Hayward N.K., Duffy D.L., Bishop J.A., Pastinen T., Cervino A., Zhao Z.Z., Deloukas P., Soranzo N. et al.

Nat. Genet. 41:915-919(2009) · Mapped (12)

Genome-wide association study identifies three loci associated with melanoma risk.

Bishop D.T., Demenais F., Iles M.M., Harland M., Taylor J.C., Corda E., Randerson-Moor J., Aitken J.F., Avril M.F., Azizi E. et al.

Nat. Genet. 41:920-925(2009) · Mapped (35)

The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population.

Hacker E., Hayward N.K., Dumenil T., James M.R., Whiteman D.C.

J. Invest. Dermatol. 130:241-248(2010) · Mapped (24)

H-cadherin expression reduces invasion of malignant melanoma.

Kuphal S., Martyn A.C., Pedley J., Crowther L.M., Bonazzi V.F., Parsons P.G., Bosserhoff A.K., Hayward N.K., Boyle G.M.

Pigment Cell Melanoma Res 22:296-306(2009) · Mapped (7)

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