| Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137. Harvey B.M., Mironenko T., Sun Y., Hong H., Deng Z., Leadlay P.F., Weissman K.J., Haydock S.F.
Chem. Biol. 14:703-714(2007) · UniProtKB (18) |
| Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338. Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F.
Nat. Biotechnol. 25:447-453(2007) · UniProtKB (7,154) |
| Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin. Sun Y., Hong H., Samborskyy M., Samboskyy M., Mironenko T., Leadlay P.F., Haydock S.F.
Microbiology (Reading, Engl.) 152:3507-3515(2006) · UniProtKB (5) |
| Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase. Austin M.B., Saito T., Bowman M.E., Haydock S., Kato A., Moore B.S., Kay R.R., Noel J.P.
Nat. Chem. Biol. 2:494-502(2006) · UniProtKB (2) · Mapped (1) |
| The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A. Huang F., Haydock S.F., Spiteller D., Mironenko T., Li T.L., O'Hagan D., Leadlay P.F., Spencer J.B.
Chem. Biol. 13:475-484(2006) · UniProtKB (12) |
| Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449. Haydock S.F., Appleyard A.N., Mironenko T., Lester J., Scott N., Leadlay P.F.
Microbiology (Reading, Engl.) 151:3161-3169(2005) · UniProtKB (28) |
| The genome of the social amoeba Dictyostelium discoideum. Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q. et al.
Nature 435:43-57(2005) · UniProtKB (12,911) |
| The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine. Huang F., Haydock S.F., Mironenko T., Spiteller D., Li Y., Spencer J.B.
Org. Biomol. Chem. 3:1410-1418(2005) · UniProtKB (21) |
| Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase. Li T.L., Huang F., Haydock S.F., Mironenko T., Leadlay P.F., Spencer J.B.
Chem. Biol. 11:107-119(2004) · UniProtKB (49) |
| Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans. Stinear T.P., Mve-Obiang A., Small P.L., Frigui W., Pryor M.J., Brosch R., Jenkin G.A., Johnson P.D., Davies J.K., Lee R.E. et al.
Proc. Natl. Acad. Sci. U.S.A. 101:1345-1349(2004) · UniProtKB (75) |
| Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase. Aparicio J.F., Molnar I., Schwecke T., Konig A., Haydock S.F., Khaw L.E., Staunton J., Leadlay P.F.
Gene 169:9-16(1996) · UniProtKB (28) |
| Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase. Molnar I., Aparicio J.F., Haydock S.F., Khaw L.E., Schwecke T., Konig A., Staunton J., Leadlay P.F.
Gene 169:1-7(1996) · UniProtKB (28) |
| The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin. Schwecke T., Aparicio J.F., Molnar I., Konig A., Khaw L.E., Haydock S.F., Oliynyk M., Caffrey P., Cortes J., Lester J.B.
Proc. Natl. Acad. Sci. U.S.A. 92:7839-7843(1995) · UniProtKB (28) |
| An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea. Cortes J., Haydock S.F., Roberts G.A., Bevitt D.J., Leadlay P.F.
Nature 348:176-178(1990) · UniProtKB (1) |
| Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases. Haydock S.F., Dowson J.A., Dhillon N., Roberts G.A., Cortes J., Leadlay P.F.
Mol. Gen. Genet. 230:120-128(1991) · UniProtKB (4) |
| 6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme. Bevitt D.J., Cortes J., Haydock S.F., Leadlay P.F.
Eur. J. Biochem. 204:39-49(1992) · UniProtKB (2) |