1 - 25 of 33 results for author:"Hasty P." in Literature citations
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| RAD51 mutants cause replication defects and chromosomal instability. Kim T.M., Ko J.H., Hu L., Kim S.A., Bishop A.J., Vijg J., Montagna C., Hasty P. Mol. Cell. Biol. 32:3663-3680(2012) · Mapped (9) |
| Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair. Dumitrache L.C., Hu L., Son M.Y., Li H., Wesevich A., Scully R., Stark J., Hasty P. Genetics 188:787-797(2011) · Mapped (4) |
| Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends. Roberts S.A., Strande N., Burkhalter M.D., Strom C., Havener J.M., Hasty P., Ramsden D.A. |
| Unlike p53, p27 failed to exhibit an anti-tumor genetic interaction with Ku80. Holcomb V.B., Vogel H., Hasty P. Cell Cycle 8:2463-2466(2009) · Mapped (24) |
| Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. Amleh A., Nair S.J., Sun J., Sutherland A., Hasty P., Li R. PLoS ONE 4:e5034-e5034(2009) · Mapped (15) |
| Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells. Li H., Choi Y.J., Hanes M.A., Marple T., Vogel H., Hasty P. Oncogene 28:1875-1878(2009) · Mapped (25) |
| TREX2 exonuclease defective cells exhibit double-strand breaks and chromosomal fragments but not Robertsonian translocations. Dumitrache L.C., Hu L., Hasty P. Mutat. Res. 662:84-87(2009) · Mapped (2) |
| DNA-PK suppresses a p53-independent apoptotic response to DNA damage. Gurley K.E., Moser R., Gu Y., Hasty P., Kemp C.J. EMBO Rep. 10:87-93(2009) · Mapped (34) |
| Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response. Holcomb V.B., Rodier F., Choi Y., Busuttil R.A., Vogel H., Vijg J., Campisi J., Hasty P. Cancer Res. 68:9497-9502(2008) · Mapped (13) |
| Effect of Ku80 deficiency on mutation frequencies and spectra at a LacZ reporter locus in mouse tissues and cells. Busuttil R.A., Munoz D.P., Garcia A.M., Rodier F., Kim W.H., Suh Y., Hasty P., Campisi J., Vijg J. PLoS ONE 3:e3458-e3458(2008) · Mapped (2) |
| ERCC1-XPF endonuclease facilitates DNA double-strand break repair. Ahmad A., Robinson A.R., Duensing A., van Drunen E., Beverloo H.B., Weisberg D.B., Hasty P., Hoeijmakers J.H., Niedernhofer L.J. Mol. Cell. Biol. 28:5082-5092(2008) · Mapped (8) |
| The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage. Bahassi E.M., Ovesen J.L., Riesenberg A.L., Bernstein W.Z., Hasty P.E., Stambrook P.J. |
| Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs. Holcomb V.B., Vogel H., Hasty P. Mech. Ageing Dev. 128:601-608(2007) · Mapped (13) |
| Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer. Li H., Vogel H., Holcomb V.B., Gu Y., Hasty P. Mol. Cell. Biol. 27:8205-8214(2007) · Mapped (7) |
| Biochemical and cellular characteristics of the 3' -> 5' exonuclease TREX2. Chen M.J., Ma S.M., Dumitrache L.C., Hasty P. Nucleic Acids Res. 35:2682-2694(2007) · UniProtKB (1) |
| Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice. van de Ven M., Andressoo J.O., Holcomb V.B., von Lindern M., Jong W.M., De Zeeuw C.I., Suh Y., Hasty P., Hoeijmakers J.H., van der Horst G.T. et al. PLoS Genet. 2:e192-e192(2006) · Mapped (14) |
| Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs. Holcomb V.B., Vogel H., Marple T., Kornegay R.W., Hasty P. Oncogene 25:7159-7165(2006) · Mapped (16) |
| Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. Donoho G., Brenneman M.A., Cui T.X., Donoviel D., Vogel H., Goodwin E.H., Chen D.J., Hasty P., Chen D.J. Genes Chromosomes Cancer 36:317-331(2003) · Mapped (4) |
| The impact energy metabolism and genome maintenance have on longevity and senescence: lessons from yeast to mammals. Hasty P. Mech. Ageing Dev. 122:1651-1662(2001) · Mapped (1) |
| Analysis of ku80-mutant mice and cells with deficient levels of p53. Lim D.S., Vogel H., Willerford D.M., Sands A.T., Platt K.A., Hasty P. Mol. Cell. Biol. 20:3772-3780(2000) · Mapped (13) |
| Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Gu Y., Sekiguchi J., Gao Y., Dikkes P., Frank K., Ferguson D., Hasty P., Chun J., Alt F.W. Proc. Natl. Acad. Sci. U.S.A. 97:2668-2673(2000) · Mapped (13) |
| Deletion of Ku86 causes early onset of senescence in mice. Vogel H., Lim D.S., Karsenty G., Finegold M., Hasty P. Proc. Natl. Acad. Sci. U.S.A. 96:10770-10775(1999) · Mapped (2) |
| Defining functional domains of Ku80: DNA end binding and survival after radiation. Osipovich O., Duhe R.J., Hasty P., Durum S.K., Muegge K. Biochem. Biophys. Res. Commun. 261:802-807(1999) · Mapped (7) |
| Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice. Vivian J.L., Klein W.H., Hasty P. BioTechniques 27:154-162(1999) · Mapped (3) |
| Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to gamma-radiation and premature senescence. Morimatsu M., Donoho G., Hasty P. Cancer Res. 58:3441-3447(1998) · Mapped (3) |