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GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline.

Ma L., Buchold G.M., Greenbaum M.P., Roy A., Burns K.H., Zhu H., Han D.Y., Harris R.A., Coarfa C., Gunaratne P.H. et al.

PLoS Genet. 5:e1000635-e1000635(2009) · Mapped (2)

Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol.

Blednov Y.A., Harris R.A.

Neuropharmacology 56:814-820(2009) · Mapped (2)

TLR activation induces TNF-alpha production from adult neural stem/progenitor cells.

Covacu R., Arvidsson L., Andersson A., Khademi M., Erlandsson-Harris H., Harris R.A., Svensson M.A., Olsson T., Brundin L.

J. Immunol. 182:6889-6895(2009) · Mapped (3)

The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases.

Guo J.P., Verdrengh M., Tarkowski A., Lange S., Jennische E., Lorentzen J.C., Harris R.A.

Genes Immun. 10:227-236(2009) · Mapped (1)

Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis.

Andersson A., Covacu R., Sunnemark D., Danilov A.I., Dal Bianco A., Khademi M., Wallstrom E., Lobell A., Brundin L., Lassmann H. et al.

J. Leukoc. Biol. 84:1248-1255(2008) · Mapped (9)

Human leukocyte antigen class II associations with hepatitis C virus clearance and virus-specific CD4 T cell response among Caucasians and African Americans.

Harris R.A., Sugimoto K., Kaplan D.E., Ikeda F., Kamoun M., Chang K.M.

Hepatology 48:70-79(2008) · Mapped (757)

Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice.

Jeoung N.H., Harris R.A.

Am. J. Physiol. Endocrinol. Metab. 295:E46-54(2008) · Mapped (2)

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.

Aragones J., Schneider M., Van Geyte K., Fraisl P., Dresselaers T., Mazzone M., Dirkx R., Zacchigna S., Lemieux H., Jeoung N.H. et al.

Nat. Genet. 40:170-180(2008) · Mapped (12)

Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.

Zhao G., Jeoung N.H., Burgess S.C., Rosaaen-Stowe K.A., Inagaki T., Latif S., Shelton J.M., McAnally J., Bassel-Duby R., Harris R.A. et al.

Am. J. Physiol. Heart Circ. Physiol. 294:H936-43(2008) · Mapped (1)

Carbohydrate-response element-binding protein deletion alters substrate utilization producing an energy-deficient liver.

Burgess S.C., Iizuka K., Jeoung N.H., Harris R.A., Kashiwaya Y., Veech R.L., Kitazume T., Uyeda K.

J. Biol. Chem. 283:1670-1678(2008) · Mapped (2)

Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation.

Lobo I.A., Harris R.A., Trudell J.R.

J. Neurochem. 104:1649-1662(2008) · Mapped (3)

Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.

Okvist A., Johansson S., Kuzmin A., Bazov I., Merino-Martinez R., Ponomarev I., Mayfield R.D., Harris R.A., Sheedy D., Garrick T. et al.

PLoS ONE 2:e930-e930(2007) · Mapped (3)

Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats.

Arikawa E., Ma R.C., Isshiki K., Luptak I., He Z., Yasuda Y., Maeno Y., Patti M.E., Weir G.C., Harris R.A. et al.

Diabetes 56:1410-1420(2007) · Mapped (1)

Identification of a novel PP2C-type mitochondrial phosphatase.

Joshi M.A., Jeoung N.H., Popov K.M., Harris R.A.

Biochem. Biophys. Res. Commun. 356:38-44(2007) · UniProtKB (2)

Reduced alcohol consumption in mice lacking preprodynorphin.

Blednov Y.A., Walker D., Martinez M., Harris R.A.

Alcohol 40:73-86(2006) · Mapped (3)

Role of endocannabinoids in alcohol consumption and intoxication: studies of mice lacking fatty acid amide hydrolase.

Blednov Y.A., Cravatt B.F., Boehm S.L., Walker D., Harris R.A.

Neuropsychopharmacology 32:1570-1582(2007) · Mapped (7)

Mutations in the gene encoding 3-hydroxyisobutyryl-CoA hydrolase results in progressive infantile neurodegeneration.

Loupatty F.J., Clayton P.T., Ruiter J.P.N., Ofman R., Ijlst L., Brown G.K., Thorburn D.R., Harris R.A., Duran M., Desousa C. et al.

Am. J. Hum. Genet. 80:195-199(2007) · UniProtKB (1)

Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice.

Joshi M.A., Jeoung N.H., Obayashi M., Hattab E.M., Brocken E.G., Liechty E.A., Kubek M.J., Vattem K.M., Wek R.C., Harris R.A.

Biochem. J. 400:153-162(2006) · Mapped (8)

An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.

Borghese C.M., Werner D.F., Topf N., Baron N.V., Henderson L.A., Boehm S.L., Blednov Y.A., Saad A., Dai S., Pearce R.A. et al.

J. Pharmacol. Exp. Ther. 319:208-218(2006) · Mapped (3)

Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression.

Kwon H.S., Huang B., Ho Jeoung N., Wu P., Steussy C.N., Harris R.A.

Biochim. Biophys. Acta 1759:141-151(2006) · Mapped (6)

Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors.

Ponomarev I., Maiya R., Harnett M.T., Schafer G.L., Ryabinin A.E., Blednov Y.A., Morikawa H., Boehm S.L., Homanics G.E., Berman A.E. et al.

J. Neurosci. 26:5673-5683(2006) · Mapped (3)

Defining the dopamine transporter proteome by convergent biochemical and in silico analyses.

Maiya R., Ponomarev I., Linse K.D., Harris R.A., Mayfield R.D.

Genes Brain Behav. 6:97-106(2007) · Mapped (11)

The DNA sequence, annotation and analysis of human chromosome 3.

Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y. et al.

Nature 440:1194-1198(2006) · UniProtKB (2,861)

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.

Mulligan M.K., Ponomarev I., Hitzemann R.J., Belknap J.K., Tabakoff B., Harris R.A., Crabbe J.C., Blednov Y.A., Grahame N.J., Phillips T.J. et al.

Proc. Natl. Acad. Sci. U.S.A. 103:6368-6373(2006) · Mapped (50)

Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.

Jeoung N.H., Wu P., Joshi M.A., Jaskiewicz J., Bock C.B., Depaoli-Roach A.A., Harris R.A.

Biochem. J. 397:417-425(2006) · Mapped (2)

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