| Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. George B., Verma R., Soofi A.A., Garg P., Zhang J., Park T.J., Giardino L., Ryzhova L., Johnstone D.B., Wong H. et al.
J. Clin. Invest. 122:674-692(2012) · Mapped (12) |
| Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness. Janostiak R., Tolde O., Bruhova Z., Novotny M., Hanks S.K., Rosel D., Brabek J.
Mol. Biol. Cell 22:4256-4267(2011) · Mapped (24) |
| KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1. Goettel J.A., Liang D., Hilliard V.C., Edelblum K.L., Broadus M.R., Gould K.L., Hanks S.K., Polk D.B.
Exp. Cell Res. 317:452-463(2011) · Mapped (5) |
| Focal adhesion kinase modulates cell adhesion strengthening via integrin activation. Michael K.E., Dumbauld D.W., Burns K.L., Hanks S.K., Garcia A.J.
Mol. Biol. Cell 20:2508-2519(2009) · Mapped (13) |
| Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity. Ciccimaro E., Hanks S.K., Blair I.A.
Mol. Pharmacol. 75:658-666(2009) · Mapped (9) |
| The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling. Kim W., Seok Kang Y., Soo Kim J., Shin N.Y., Hanks S.K., Song W.K.
Mol. Biol. Cell 19:2135-2146(2008) · Mapped (27) |
| p130CAS is required for netrin signaling and commissural axon guidance. Liu G., Li W., Gao X., Li X., Jurgensen C., Park H.T., Shin N.Y., Yu J., He M.L., Hanks S.K. et al.
J. Neurosci. 27:957-968(2007) · Mapped (24) |
| Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B. Rivera G.M., Antoku S., Gelkop S., Shin N.Y., Hanks S.K., Pawson T., Mayer B.J.
Proc. Natl. Acad. Sci. U.S.A. 103:9536-9541(2006) · Mapped (13) |
| CD98 modulates integrin beta1 function in polarized epithelial cells. Cai S., Bulus N., Fonseca-Siesser P.M., Chen D., Hanks S.K., Pozzi A., Zent R.
J. Cell. Sci. 118:889-899(2005) · Mapped (11) |
| CAS promotes invasiveness of Src-transformed cells. Brabek J., Constancio S.S., Shin N.Y., Pozzi A., Weaver A.M., Hanks S.K.
Oncogene 23:7406-7415(2004) · Mapped (9) |
| Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion. Yano H., Mazaki Y., Kurokawa K., Hanks S.K., Matsuda M., Sabe H.
J. Cell Biol. 166:283-295(2004) · Mapped (2) |
| Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. Shin N.Y., Dise R.S., Schneider-Mergener J., Ritchie M.D., Kilkenny D.M., Hanks S.K.
J. Biol. Chem. 279:38331-38337(2004) · Mapped (4) |
| Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Kurenova E., Xu L.H., Yang X., Baldwin A.S. Jr., Craven R.J., Hanks S.K., Liu Z.G., Cance W.G.
Mol. Cell. Biol. 24:4361-4371(2004) · Mapped (2) |
| Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes. Torsoni A.S., Constancio S.S., Nadruz W. Jr., Hanks S.K., Franchini K.G.
Circ. Res. 93:140-147(2003) · Mapped (3) |
| c-Jun is essential for organization of the epidermal leading edge. Li G., Gustafson-Brown C., Hanks S.K., Nason K., Arbeit J.M., Pogliano K., Wisdom R.M., Johnson R.S.
Dev. Cell 4:865-877(2003) · Mapped (11) |
| Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility. Hanks S.K., Ryzhova L., Shin N.Y., Brabek J.
Front. Biosci. 8:d982-96(2003) · Mapped (9) |
| An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans. Miller M.A., Ruest P.J., Kosinski M., Hanks S.K., Greenstein D.
Genes Dev. 17:187-200(2003) · Mapped (16) |
| Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity. Donaldson J.C., Dise R.S., Ritchie M.D., Hanks S.K.
J. Biol. Chem. 277:29028-29035(2002) · UniProtKB (1) |
| FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v-Src, but is not a critical determinant of v-Src transformation. Roy S., Ruest P.J., Hanks S.K.
J. Cell. Biochem. 84:377-388(2002) · Mapped (22) |
| Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells. Donaldson J.C., Dempsey P.J., Reddy S., Bouton A.H., Coffey R.J., Hanks S.K.
Exp. Cell Res. 256:168-178(2000) · UniProtKB (3) · Mapped (20) |
| Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2. Owen J.D., Ruest P.J., Fry D.W., Hanks S.K.
Mol. Cell. Biol. 19:4806-4818(1999) · UniProtKB (1) |
| Chicken and mouse focal adhesion kinases are similar in structure at their amino termini. Devor B.B., Zhang X., Patel S.K., Polte T.R., Hanks S.K.
Biochem. Biophys. Res. Commun. 190:1084-1089(1993) · UniProtKB (1) |
| Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Schlaepfer D.D., Hanks S.K., Hunter T., van der Geer P.
Nature 372:786-791(1994) · UniProtKB (2) · Mapped (14) |
| Phosphorylation of E2F-1 by cyclin A-cdk2. Kitagawa M., Higashi H., Suzuki-Takahashi I., Segawa K., Hanks S.K., Taya Y., Nishimura S., Okuyama A.
Oncogene 10:229-236(1995) · UniProtKB (1) |
| Cloning of a Xenopus laevis cDNA encoding focal adhesion kinase (FAK) and expression during early development. Zhang X., Wright C.V., Hanks S.K.
Gene 160:219-222(1995) · UniProtKB (1) |
