| Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Zhao Y., Biertumpfel C., Gregory M.T., Hua Y.J., Hanaoka F., Yang W.
Proc. Natl. Acad. Sci. U.S.A. 109:7269-7274(2012) · Mapped (5) |
| A DNA oligomer containing 2,2,4-triamino-5(2H)-oxazolone is incised by human NEIL1 and NTH1. Kino K., Takao M., Miyazawa H., Hanaoka F.
Mutat. Res. 734:73-77(2012) · Mapped (3) |
| The vital role of polymerase zeta and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase zeta by REV1 to replication-stalled site. Hashimoto K., Cho Y., Yang I.Y., Akagi J., Ohashi E., Tateishi S., de Wind N., Hanaoka F., Ohmori H., Moriya M.
J. Biol. Chem. 287:9613-9622(2012) · Mapped (16) |
| Stalled Poleta at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1. Ito W., Yokoi M., Sakayoshi N., Sakurai Y., Akagi J., Mitani H., Hanaoka F.
Genes Cells 17:98-108(2012) · Mapped (2) |
| Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation. Kano C., Hanaoka F., Wang J.Y.
Int. Immunol. 24:169-174(2012) · Mapped (4) |
| The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation. Fischer E.S., Scrima A., Bohm K., Matsumoto S., Lingaraju G.M., Faty M., Yasuda T., Cavadini S., Wakasugi M., Hanaoka F. et al.
Cell 147:1024-1039(2011) · UniProtKB (1) · Mapped (6) |
| Hst3 and Hst4 histone deacetylases regulate replicative lifespan by preventing genome instability in Saccharomyces cerevisiae. Hachinohe M., Hanaoka F., Masumoto H.
Genes Cells 16:467-477(2011) · Mapped (1) |
| Genetic analyses using a mouse cell cycle mutant identifies magoh as a novel gene involved in Cdk regulation. Inaki M., Kato D., Utsugi T., Onoda F., Hanaoka F., Murakami Y.
Genes Cells 16:166-178(2011) · Mapped (6) |
| Stimulation of DNA glycosylase activities by XPC Protein Complex: Roles of protein-protein interactions. Shimizu Y., Uchimura Y., Dohmae N., Saitoh H., Hanaoka F., Sugasawa K.
J. Nucleic Acids 2010:0-0(2010) · UniProtKB (2) |
| Structure and mechanism of human DNA polymerase eta. Biertumpfel C., Zhao Y., Kondo Y., Ramon-Maiques S., Gregory M., Lee J.Y., Masutani C., Lehmann A.R., Hanaoka F., Yang W.
Nature 465:1044-1048(2010) · Mapped (5) |
| Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins. Jee J., Mizuno T., Kamada K., Tochio H., Chiba Y., Yanagi K., Yasuda G., Hiroaki H., Hanaoka F., Shirakawa M.
J. Biol. Chem. 285:15931-15940(2010) · Mapped (2) |
| The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Sekimoto T., Oda T., Pozo F.M., Murakumo Y., Masutani C., Hanaoka F., Yamashita T.
Mol. Cell 37:79-89(2010) · Mapped (9) |
| Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning. Sugasawa K., Akagi J., Nishi R., Iwai S., Hanaoka F.
Mol. Cell 36:642-653(2009) · UniProtKB (2) |
| Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides. Katafuchi A., Sassa A., Niimi N., Gruz P., Fujimoto H., Masutani C., Hanaoka F., Ohta T., Nohmi T.
Nucleic Acids Res. 38:859-867(2010) · Mapped (12) |
| The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A. Takemoto A., Maeshima K., Ikehara T., Yamaguchi K., Murayama A., Imamura S., Imamoto N., Yokoyama S., Hirano T., Watanabe Y. et al.
Nat. Struct. Mol. Biol. 16:1302-1308(2009) · Mapped (3) |
| Aberrant DNA polymerase alpha is excluded from the nucleus by defective import and degradation in the nucleus. Eichinger C.S., Mizuno T., Mizuno K., Miyake Y., Yanagi K., Imamoto N., Hanaoka F.
J. Biol. Chem. 284:30604-30614(2009) · Mapped (3) |
| A novel interaction between human DNA polymerase eta and MutLalpha. Kanao R., Hanaoka F., Masutani C.
Biochem. Biophys. Res. Commun. 389:40-45(2009) · Mapped (39) |
| Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus. Fukuda H., Takamura-Enya T., Masuda Y., Nohmi T., Seki C., Kamiya K., Sugimura T., Masutani C., Hanaoka F., Nakagama H.
J. Biol. Chem. 284:25585-25592(2009) · Mapped (10) |
| Cyclin A-Cdk1 regulates the origin firing program in mammalian cells. Katsuno Y., Suzuki A., Sugimura K., Okumura K., Zineldeen D.H., Shimada M., Niida H., Mizuno T., Hanaoka F., Nakanishi M.
Proc. Natl. Acad. Sci. U.S.A. 106:3184-3189(2009) · Mapped (1) |
| Central forkhead domain of human TFIIE beta plays a primary role in binding double-stranded DNA at transcription initiation. Tanaka A., Watanabe T., Iida Y., Hanaoka F., Ohkuma Y.
Genes Cells 14:395-405(2009) · Mapped (1) |
| Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. Akagi J., Masutani C., Kataoka Y., Kan T., Ohashi E., Mori T., Ohmori H., Hanaoka F.
DNA Repair (Amst.) 8:585-599(2009) · Mapped (8) |
| DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation. Masuda K., Ouchida R., Yokoi M., Hanaoka F., Azuma T., Wang J.Y.
Eur. J. Immunol. 38:2796-2805(2008) · Mapped (2) |
| Schizosaccharomyces pombe Ddb1 recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box. Fukumoto Y., Dohmae N., Hanaoka F.
Mol. Cell. Biol. 28:6746-6756(2008) · UniProtKB (4) · Mapped (1) |
| Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. Martomo S.A., Saribasak H., Yokoi M., Hanaoka F., Gearhart P.J.
DNA Repair (Amst.) 7:1603-1608(2008) · Mapped (7) |
| Use of RNAi in C. elegans. Ohkumo T., Masutani C., Eki T., Hanaoka F.
Methods Mol. Biol. 442:129-137(2008) · Mapped (1) |
