1 - 25 of 43 results for author:"Griffin P.R." in Literature citations
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| TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Ye L., Kleiner S., Wu J., Sah R., Gupta R.K., Banks A.S., Cohen P., Khandekar M.J., Bostrom P., Mepani R.J. et al. Cell 151:96-110(2012) · Mapped (5) |
| Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation. Musille P.M., Pathak M.C., Lauer J.L., Hudson W.H., Griffin P.R., Ortlund E.A. Nat. Struct. Mol. Biol. 19:532-7, 2012:S1-2(2012) · Mapped (11) |
| Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases. Ng L.M., Soon F.F., Zhou X.E., West G.M., Kovach A., Suino-Powell K.M., Chalmers M.J., Li J., Yong E.L., Zhu J.K. et al. Proc. Natl. Acad. Sci. U.S.A. 108:21259-21264(2011) · Mapped (2) |
| Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Soon F.F., Ng L.M., Zhou X.E., West G.M., Kovach A., Tan M.H., Suino-Powell K.M., He Y., Xu Y., Chalmers M.J. et al. Science 335:85-88(2012) · Mapped (5) |
| Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1alpha/ERRgamma complex. Devarakonda S., Gupta K., Chalmers M.J., Hunt J.F., Griffin P.R., Van Duyne G.D., Spiegelman B.M. Proc. Natl. Acad. Sci. U.S.A. 108:18678-18683(2011) · Mapped (17) |
| Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors. Malapaka R.R., Khoo S., Zhang J., Choi J.H., Zhou X.E., Xu Y., Gong Y., Li J., Yong E.L., Chalmers M.J. et al. J. Biol. Chem. 287:183-195(2012) · Mapped (2) |
| Ligand-dependent perturbation of the conformational ensemble for the GPCR beta2 adrenergic receptor revealed by HDX. West G.M., Chien E.Y., Katritch V., Gatchalian J., Chalmers M.J., Stevens R.C., Griffin P.R. Structure 19:1424-1432(2011) · Mapped (2) |
| A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Lee J.M., Lee Y.K., Mamrosh J.L., Busby S.A., Griffin P.R., Pathak M.C., Ortlund E.A., Moore D.D. Nature 474:506-510(2011) · Mapped (13) |
| DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex. Zhang J., Chalmers M.J., Stayrook K.R., Burris L.L., Wang Y., Busby S.A., Pascal B.D., Garcia-Ordonez R.D., Bruning J.B., Istrate M.A. et al. Nat. Struct. Mol. Biol. 18:556-563(2011) · Mapped (6) |
| The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1. Heidebrecht T., Christodoulou E., Chalmers M.J., Jan S., Ter Riet B., Grover R.K., Joosten R.P., Littler D., van Luenen H., Griffin P.R. et al. Nucleic Acids Res. 39:5715-5728(2011) · UniProtKB (1) |
| Helix 11 dynamics is critical for constitutive androstane receptor activity. Wright E., Busby S.A., Wisecarver S., Vincent J., Griffin P.R., Fernandez E.J. Structure 19:37-44(2011) · Mapped (4) |
| Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer. Zhang J., Chalmers M.J., Stayrook K.R., Burris L.L., Garcia-Ordonez R.D., Pascal B.D., Burris T.P., Dodge J.A., Griffin P.R. Structure 18:1332-1341(2010) · Mapped (13) |
| Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Choi J.H., Banks A.S., Estall J.L., Kajimura S., Bostrom P., Laznik D., Ruas J.L., Chalmers M.J., Kamenecka T.M., Bluher M. et al. Nature 466:451-456(2010) · Mapped (20) |
| Regulation of adipogenesis by natural and synthetic REV-ERB ligands. Kumar N., Solt L.A., Wang Y., Rogers P.M., Bhattacharyya G., Kamenecka T.M., Stayrook K.R., Crumbley C., Floyd Z.E., Gimble J.M. et al. Endocrinology 151:3015-3025(2010) · Mapped (6) |
| A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol). Wang Y., Kumar N., Crumbley C., Griffin P.R., Burris T.P. Biochim. Biophys. Acta 1801:917-923(2010) · Mapped (9) |
| Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands. Wang Y., Kumar N., Solt L.A., Richardson T.I., Helvering L.M., Crumbley C., Garcia-Ordonez R.D., Stayrook K.R., Zhang X., Novick S. et al. J. Biol. Chem. 285:5013-5025(2010) · Mapped (16) |
| Unique ligand binding patterns between estrogen receptor alpha and beta revealed by hydrogen-deuterium exchange. Dai S.Y., Burris T.P., Dodge J.A., Montrose-Rafizadeh C., Wang Y., Pascal B.D., Chalmers M.J., Griffin P.R. Biochemistry 48:9668-9676(2009) · Mapped (58) |
| Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network. Avvaru B.S., Busby S.A., Chalmers M.J., Griffin P.R., Venkatakrishnan B., Agbandje-McKenna M., Silverman D.N., McKenna R. Biochemistry 48:7365-7372(2009) · UniProtKB (1) · Mapped (1) |
| Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Dai S.Y., Chalmers M.J., Bruning J., Bramlett K.S., Osborne H.E., Montrose-Rafizadeh C., Barr R.J., Wang Y., Wang M., Burris T.P. et al. Proc. Natl. Acad. Sci. U.S.A. 105:7171-7176(2008) · Mapped (1) |
| Partial agonists activate PPARgamma using a helix 12 independent mechanism. Bruning J.B., Chalmers M.J., Prasad S., Busby S.A., Kamenecka T.M., He Y., Nettles K.W., Griffin P.R. Structure 15:1258-1271(2007) · Mapped (1) |
| Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators. Hamuro Y., Coales S.J., Morrow J.A., Molnar K.S., Tuske S.J., Southern M.R., Griffin P.R. Protein Sci. 15:1883-1892(2006) · Mapped (9) |
| Growth hormone secretagogue receptor family members and ligands. Smith R.G., Leonard R., Bailey A.R.T., Palyha O.C., Feighner S.D., Tan C.P., Mckee K.K., Pong S.-S., Griffin P.R., Howard A.D. Endocrine 14:9-14(2001) · UniProtKB (2) |
| Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity. Carmen A.A., Griffin P.R., Calaycay J.R., Rundlett S.E., Suka Y., Grunstein M. Proc. Natl. Acad. Sci. U.S.A. 96:12356-12361(1999) · UniProtKB (1) · Mapped (1) |
| Primary structure of gamma-bungarotoxin, a new postsynaptic neurotoxin from venom of Bungarus multicinctus. Aird S.D., Womble G.C., Yates J.R. III, Griffin P.R. Toxicon 37:609-625(1999) · UniProtKB (1) |
| A receptor in pituitary and hypothalamus that functions in growth hormone release. Howard A.D., Feighner S.D., Cully D.F., Arena J.P., Liberator P.A., Rosenblum C.I., Hamelin M., Hreniuk D.L., Palyha O.C., Anderson J. et al. Science 273:974-977(1996) · UniProtKB (2) |