1 - 25 of 56 results for author:"Granzier H." in Literature citations
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| Titin is a major human disease gene. LeWinter M.M., Granzier H.L. Circulation 127:938-944(2013) · Mapped (13) |
| Single molecule force spectroscopy on titin implicates immunoglobulin domain stability as a cardiac disease mechanism. Anderson B.R., Bogomolovas J., Labeit S., Granzier H. J. Biol. Chem. 288:5303-5315(2013) · Mapped (21) |
| CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban. Wu Y., Luczak E.D., Lee E.J., Hidalgo C., Yang J., Gao Z., Li J., Wehrens X.H., Granzier H., Anderson M.E. J. Mol. Cell. Cardiol. 53:429-436(2012) · Mapped (4) |
| A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics. Raskin A., Lange S., Banares K., Lyon R.C., Zieseniss A., Lee L.K., Yamazaki K.G., Granzier H.L., Gregorio C.C., McCulloch A.D. et al. J. Biol. Chem. 287:29273-29284(2012) · Mapped (74) |
| Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. Sheikh F., Ouyang K., Campbell S.G., Lyon R.C., Chuang J., Fitzsimons D., Tangney J., Hidalgo C.G., Chung C.S., Cheng H. et al. J. Clin. Invest. 122:1209-1221(2012) · Mapped (8) |
| Titin-based stiffening of muscle fibers in Ehlers-Danlos Syndrome. Ottenheijm C.A., Voermans N.C., Hudson B.D., Irving T., Stienen G.J., van Engelen B.G., Granzier H. J. Appl. Physiol. 112:1157-1165(2012) · Mapped (13) |
| Titin-actin interaction: PEVK-actin-based viscosity in a large animal. Chung C.S., Bogomolovas J., Gasch A., Hidalgo C.G., Labeit S., Granzier H.L. J. Biomed. Biotechnol. 2011:310791-310791(2011) · Mapped (1) |
| Mechanics on myocardium deficient in the N2B region of titin: the cardiac-unique spring element improves efficiency of the cardiac cycle. Nedrud J., Labeit S., Gotthardt M., Granzier H. Biophys. J. 101:1385-1392(2011) · Mapped (21) |
| Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunction. Hudson B., Hidalgo C., Saripalli C., Granzier H. Circ. Res. 109:858-866(2011) · Mapped (21) |
| Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromes. Taylor M., Graw S., Sinagra G., Barnes C., Slavov D., Brun F., Pinamonti B., Salcedo E.E., Sauer W., Pyxaras S. et al. Circulation 124:876-885(2011) · Mapped (13) |
| Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart. Knoll R., Linke W.A., Zou P., Miocic S., Kostin S., Buyandelger B., Ku C.H., Neef S., Bug M., Schafer K. et al. Circ. Res. 109:758-769(2011) · Mapped (3) |
| Titin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions. Chung C.S., Methawasin M., Nelson O.L., Radke M.H., Hidalgo C.G., Gotthardt M., Granzier H.L. J. Mol. Cell. Cardiol. 51:428-434(2011) · Mapped (21) |
| Contribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle. Chung C.S., Granzier H.L. J. Mol. Cell. Cardiol. 50:731-739(2011) · Mapped (21) |
| Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury. Ali M.A., Cho W.J., Hudson B., Kassiri Z., Granzier H., Schulz R. Circulation 122:2039-2047(2010) · Mapped (40) |
| Modulation of muscle atrophy, fatigue and MLC phosphorylation by MuRF1 as indicated by hindlimb suspension studies on MuRF1-KO mice. Labeit S., Kohl C.H., Witt C.C., Labeit D., Jung J., Granzier H. J. Biomed. Biotechnol. 2010:693741-693741(2010) · Mapped (8) |
| Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy. Ojima K., Kawabata Y., Nakao H., Nakao K., Doi N., Kitamura F., Ono Y., Hata S., Suzuki H., Kawahara H. et al. J. Clin. Invest. 120:2672-2683(2010) · Mapped (14) |
| Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice. Lee E.J., Peng J., Radke M., Gotthardt M., Granzier H.L. J. Mol. Cell. Cardiol. 49:449-458(2010) · Mapped (21) |
| Cardiac titin: a multifunctional giant. LeWinter M.M., Granzier H. Circulation 121:2137-2145(2010) · Mapped (13) |
| Titin-isoform dependence of titin-actin interaction and its regulation by S100A1/Ca2+ in skinned myocardium. Fukushima H., Chung C.S., Granzier H. J. Biomed. Biotechnol. 2010:727239-727239(2010) · Mapped (13) |
| MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance. Moriscot A.S., Baptista I.L., Bogomolovas J., Witt C., Hirner S., Granzier H., Labeit S. J. Struct. Biol. 170:344-353(2010) · Mapped (4) |
| The effects of PKCalpha phosphorylation on the extensibility of titin's PEVK element. Anderson B.R., Bogomolovas J., Labeit S., Granzier H. J. Struct. Biol. 170:270-277(2010) · Mapped (4) |
| Reduced myofibrillar connectivity and increased Z-disk width in nebulin-deficient skeletal muscle. Tonino P., Pappas C.T., Hudson B.D., Labeit S., Gregorio C.C., Granzier H. J. Cell. Sci. 123:384-391(2010) · Mapped (12) |
| Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2). Ottenheijm C.A., Hooijman P., DeChene E.T., Stienen G.J., Beggs A.H., Granzier H. J. Struct. Biol. 170:334-343(2010) · Mapped (14) |
| Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost. Chandra M., Mamidi R., Ford S., Hidalgo C., Witt C., Ottenheijm C., Labeit S., Granzier H. J. Biol. Chem. 284:30889-30896(2009) · Mapped (12) |
| Altered contractility of skeletal muscle in mice deficient in titin's M-band region. Ottenheijm C.A., Hidalgo C., Rost K., Gotthardt M., Granzier H. J. Mol. Biol. 393:10-26(2009) · Mapped (21) |

