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1 - 25 of 35 results for author:"Gottschling D.E." in Literature citations

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Spindle pole bodies exploit the mitotic exit network in metaphase to drive their age-dependent segregation.

Hotz M., Leisner C., Chen D., Manatschal C., Wegleiter T., Ouellet J., Lindstrom D., Gottschling D.E., Vogel J., Barral Y.

Cell 148:958-972(2012)

Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae.

Lindstrom D.L., Leverich C.K., Henderson K.A., Gottschling D.E.

PLoS Genet. 7:e1002015-e1002015(2011) · Mapped (5)

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.

Rosenbaum J.C., Fredrickson E.K., Oeser M.L., Garrett-Engele C.M., Locke M.N., Richardson L.A., Nelson Z.W., Hetrick E.D., Milac T.I., Gottschling D.E. et al.

Mol. Cell 41:93-106(2011) · Mapped (3)

The mother enrichment program: a genetic system for facile replicative life span analysis in Saccharomyces cerevisiae.

Lindstrom D.L., Gottschling D.E.

Genetics 183:413-22, 2009:1SI-13SI(2009) · Mapped (5)

Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains.

Dimitrov L.N., Brem R.B., Kruglyak L., Gottschling D.E.

Genetics 183:365-383(2009) · UniProtKB (1) · Mapped (4)

Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect.

Veatch J.R., McMurray M.A., Nelson Z.W., Gottschling D.E.

Cell 137:1247-1258(2009) · Mapped (8)

A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae.

Andersen M.P., Nelson Z.W., Hetrick E.D., Gottschling D.E.

Genetics 179:1179-1195(2008) · UniProtKB (2) · Mapped (59)

Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core.

van Welsem T., Frederiks F., Verzijlbergen K.F., Faber A.W., Nelson Z.W., Egan D.A., Gottschling D.E., van Leeuwen F.

Mol. Cell. Biol. 28:3861-3872(2008) · Mapped (4)

Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin.

Gardner R.G., Nelson Z.W., Gottschling D.E.

Mol. Cell. Biol. 25:6123-6139(2005) · Mapped (3)

Degradation-mediated protein quality control in the nucleus.

Gardner R.G., Nelson Z.W., Gottschling D.E.

Cell 120:803-815(2005) · Mapped (7)

Mutations in the nucleosome core enhance transcriptional silencing.

Xu E.Y., Bi X., Holland M.J., Gottschling D.E., Broach J.R.

Mol. Cell. Biol. 25:1846-1859(2005) · Mapped (2)

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote.

Schuebeler D., MacAlpine D.M., Scalzo D., Wirbelauer C., Kooperberg C., van Leeuwen F., Gottschling D.E., O'Neill L.P., Turner B.M., Delrow J. et al.

Genes Dev. 18:1263-1271(2004) · UniProtKB (1) · Mapped (1)

An age-induced switch to a hyper-recombinational state.

McMurray M.A., Gottschling D.E.

Science 301:1908-1911(2003) · Mapped (2)

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.

Stellwagen A.E., Haimberger Z.W., Veatch J.R., Gottschling D.E.

Genes Dev. 17:2384-2395(2003) · UniProtKB (2)

Heritable chromatin structure: mapping "memory" in histones H3 and H4.

Smith C.M., Haimberger Z.W., Johnson C.O., Wolf A.J., Gafken P.R., Zhang Z., Parthun M.R., Gottschling D.E.

Proc. Natl. Acad. Sci. U.S.A. 99 Suppl 4:16454-16461(2002) · Mapped (2)

A quantitative assay for telomere protection in Saccharomyces cerevisiae.

DuBois M.L., Haimberger Z.W., McIntosh M.W., Gottschling D.E.

Genetics 161:995-1013(2002) · Mapped (4)

Dot1p modulates silencing in yeast by methylation of the nucleosome core.

van Leeuwen F., Gafken P.R., Gottschling D.E.

Cell 109:745-756(2002) · UniProtKB (1) · Mapped (1)

Identification of a small molecule inhibitor of Sir2p.

Bedalov A., Gatbonton T., Irvine W.P., Gottschling D.E., Simon J.A.

Proc. Natl. Acad. Sci. U.S.A. 98:15113-15118(2001) · Mapped (5)

Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere.

Diede S.J., Gottschling D.E.

Curr. Biol. 11:1336-1340(2001) · Mapped (4)

The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.

Peterson S.E., Stellwagen A.E., Diede S.J., Singer M.S., Haimberger Z.W., Johnson C.O., Tzoneva M., Gottschling D.E.

Nat. Genet. 27:64-67(2001) · Mapped (5)

Gene silencing: two faces of SIR2.

Gottschling D.E.

Curr. Biol. 10:R708-11(2000) · Mapped (1)

Type B histone acetyltransferase Hat1p participates in telomeric silencing.

Kelly T.J., Qin S., Gottschling D.E., Parthun M.R.

Mol. Cell. Biol. 20:7051-7058(2000) · UniProtKB (2)

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

Diede S.J., Gottschling D.E.

Cell 99:723-733(1999) · UniProtKB (1) · Mapped (4)

DOT4 links silencing and cell growth in Saccharomyces cerevisiae.

Kahana A., Gottschling D.E.

Mol. Cell. Biol. 19:6608-6620(1999) · Mapped (6)

Telomeric chromatin modulates replication timing near chromosome ends.

Stevenson J.B., Gottschling D.E.

Genes Dev. 13:146-151(1999) · Mapped (1)

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