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Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla.

Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S., Wollam A., Shah N., Wang C., Magrini V., Wilson R.K. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009) · UniProtKB (6,306)

Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont.

Koropatkin N., Martens E.C., Gordon J.I., Smith T.J.

Biochemistry 48:1532-1542(2009) · Mapped (1)

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41.

Samuel B.S., Shaito A., Motoike T., Rey F.E., Backhed F., Manchester J.K., Hammer R.E., Williams S.C., Crowley J., Yanagisawa M. et al.

Proc. Natl. Acad. Sci. U.S.A. 105:16767-16772(2008) · Mapped (5)

Innate immunity and intestinal microbiota in the development of Type 1 diabetes.

Wen L., Ley R.E., Volchkov P.Y., Stranges P.B., Avanesyan L., Stonebraker A.C., Hu C., Wong F.S., Szot G.L., Bluestone J.A. et al.

Nature 455:1109-1113(2008) · Mapped (11)

Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices.

Koropatkin N.M., Martens E.C., Gordon J.I., Smith T.J.

Structure 16:1105-1115(2008) · Mapped (1)

Evolution of symbiotic bacteria in the distal human intestine.

Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P. et al.

PLoS Biol. 5:1574-1586(2007) · UniProtKB (7,813)

Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut.

Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B., Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.

Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007) · UniProtKB (1,783)

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice.

Backhed F., Manchester J.K., Semenkovich C.F., Gordon J.I.

Proc. Natl. Acad. Sci. U.S.A. 104:979-984(2007) · Mapped (3)

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor.

Backhed F., Crawford P.A., O'Donnell D., Gordon J.I.

Proc. Natl. Acad. Sci. U.S.A. 104:606-611(2007) · Mapped (3)

Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection.

Rawls J.F., Mahowald M.A., Ley R.E., Gordon J.I.

Cell 127:423-433(2006) · Mapped (16)

The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression.

Oh J.D., Kling-Baeckhed H., Giannakis M., Xu J., Fulton R.S., Fulton L.A., Cordum H.S., Wang C., Elliott G., Edwards J. et al.

Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006) · UniProtKB (1,541)

A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism.

Samuel B.S., Gordon J.I.

Proc. Natl. Acad. Sci. U.S.A. 103:10011-10016(2006) · UniProtKB (11)

Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach.

Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P. et al.

Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006) · UniProtKB (5,193)

Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development.

Zhang X., Stappenbeck T.S., White A.C., Lavine K.J., Gordon J.I., Ornitz D.M.

Development 133:173-180(2006) · Mapped (41)

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury.

Pull S.L., Doherty J.M., Mills J.C., Gordon J.I., Stappenbeck T.S.

Proc. Natl. Acad. Sci. U.S.A. 102:99-104(2005) · Mapped (17)

The gut microbiota as an environmental factor that regulates fat storage.

Backhed F., Ding H., Wang T., Hooper L.V., Koh G.Y., Nagy A., Semenkovich C.F., Gordon J.I.

Proc. Natl. Acad. Sci. U.S.A. 101:15718-15723(2004) · Mapped (14)

Fibroblast growth factor receptor signalling is crucial for liver homeostasis and regeneration.

Steiling H., Wustefeld T., Bugnon P., Brauchle M., Fassler R., Teupser D., Thiery J., Gordon J.I., Trautwein C., Werner S.

Oncogene 22:4380-4388(2003) · Mapped (22)

A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.

Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.

Science 299:2074-2076(2003) · UniProtKB (4,773)

Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing.

Lin S.S., Manchester J.K., Gordon J.I.

J. Biol. Chem. 278:13390-13397(2003) · UniProtKB (1) · Mapped (9)

Angiogenins: a new class of microbicidal proteins involved in innate immunity.

Hooper L.V., Stappenbeck T.S., Hong C.V., Gordon J.I.

Nat. Immunol. 4:269-273(2003) · UniProtKB (1) · Mapped (2)

Colonization of germ-free transgenic mice with genotyped Helicobacter pylori strains from a case-control study of gastric cancer reveals a correlation between host responses and HsdS components of type I restriction-modification systems.

Bjorkholm B.M., Guruge J.L., Oh J.D., Syder A.J., Salama N., Guillemin K., Falkow S., Nilsson C., Falk P.G., Engstrand L. et al.

J. Biol. Chem. 277:34191-34197(2002) · UniProtKB (1)

Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.

Anderson R.M., Bitterman K.J., Wood J.G., Medvedik O., Cohen H., Lin S.S., Manchester J.K., Gordon J.I., Sinclair D.A.

J. Biol. Chem. 277:18881-18890(2002) · UniProtKB (1) · Mapped (5)

Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling.

Wong M.H., Huelsken J., Birchmeier W., Gordon J.I.

J. Biol. Chem. 277:15843-15850(2002) · Mapped (3)

Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium.

Jacobsen C.M., Narita N., Bielinska M., Syder A.J., Gordon J.I., Wilson D.B.

Dev. Biol. 241:34-46(2002) · Mapped (10)

Comparison of genetic divergence and fitness between two subclones of Helicobacter pylori.

Bjorkholm B., Lundin A., Sillen A., Guillemin K., Salama N., Rubio C., Gordon J.I., Falk P., Engstrand L.

Infect. Immun. 69:7832-7838(2001) · UniProtKB (1)

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