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22 results for author:"Godley L.A." in Literature citations

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Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.

Ostler K.R., Yang Q., Looney T.J., Zhang L., Vasanthakumar A., Tian Y., Kocherginsky M., Raimondi S.L., DeMaio J.G., Salwen H.R. et al.

Cancer Res. 72:4714-4723(2012) · Mapped (7)

Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.

Yamazaki J., Taby R., Vasanthakumar A., Macrae T., Ostler K.R., Shen L., Kantarjian H.M., Estecio M.R., Jelinek J., Godley L.A. et al.

Epigenetics 7:201-207(2012) · Mapped (2)

Dnmt3a is essential for hematopoietic stem cell differentiation.

Challen G.A., Sun D., Jeong M., Luo M., Jelinek J., Berg J.S., Bock C., Vasanthakumar A., Gu H., Xi Y. et al.

Nat. Genet. 44:23-31(2012) · Mapped (19)

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.

Szulwach K.E., Li X., Li Y., Song C.X., Wu H., Dai Q., Irier H., Upadhyay A.K., Gearing M., Levey A.I. et al.

Nat. Neurosci. 14:1607-1616(2011) · Mapped (3)

DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.

Shaknovich R., Cerchietti L., Tsikitas L., Kormaksson M., De S., Figueroa M.E., Ballon G., Yang S.N., Weinhold N., Reimers M. et al.

Blood 118:3559-3569(2011) · Mapped (7)

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.

Pronier E., Almire C., Mokrani H., Vasanthakumar A., Simon A., da Costa Reis Monte Mor B., Masse A., Le Couedic J.P., Pendino F., Carbonne B. et al.

Blood 118:2551-2555(2011) · Mapped (2)

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

Moran-Crusio K., Reavie L., Shih A., Abdel-Wahab O., Ndiaye-Lobry D., Lobry C., Figueroa M.E., Vasanthakumar A., Patel J., Zhao X. et al.

Cancer Cell 20:11-24(2011) · UniProtKB (1) · Mapped (5)

Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.

Woloszynska-Read A., Zhang W., Yu J., Link P.A., Mhawech-Fauceglia P., Collamat G., Akers S.N., Ostler K.R., Godley L.A., Odunsi K. et al.

Clin. Cancer Res. 17:2170-2180(2011) · Mapped (19)

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

Figueroa M.E., Abdel-Wahab O., Lu C., Ward P.S., Patel J., Shih A., Li Y., Bhagwat N., Vasanthakumar A., Fernandez H.F. et al.

Cancer Cell 18:553-567(2010) · Mapped (15)

Identification and molecular characterization of a novel 3′ mutation in RUNX1 in a family with familial platelet disorder.

Churpek J.E., Garcia J.S., Madzo J., Jackson S.A., Onel K., Godley L.A.

Leuk. Lymphoma 51:1931-1935(2010) · Mapped (2)

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

Shah M.Y., Vasanthakumar A., Barnes N.Y., Figueroa M.E., Kamp A., Hendrick C., Ostler K.R., Davis E.M., Lin S., Anastasi J. et al.

Cancer Res. 70:5840-5850(2010) · Mapped (27)

The identification and characterisation of novel KIT transcripts in aggressive mast cell malignancies and normal CD34+ cells.

Ozer O., Zhao Y.D., Ostler K.R., Akin C., Anastasi J., Vardiman J.W., Godley L.A.

Leuk. Lymphoma 49:1567-1577(2008) · Mapped (7)

Implications of FLT3 mutations in the therapy of acute myeloid leukemia.

Mattison R.J., Ostler K.R., Locke F.L., Godley L.A.

Rev Recent Clin Trials 2:135-141(2007) · Mapped (2)

Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins.

Ostler K.R., Davis E.M., Payne S.L., Gosalia B.B., Exposito-Cespedes J., Le Beau M.M., Godley L.A.

Oncogene 26:5553-5563(2007) · UniProtKB (1) · Mapped (6)

Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).

Lai F., Godley L.A., Joslin J., Fernald A.A., Liu J., Espinosa R. III, Zhao N., Pamintuan L., Till B.G., Larson R.A. et al.

Genomics 71:235-245(2001) · UniProtKB (1)

cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.

Lai F., Godley L.A., Fernald A.A., Orelli B.J., Pamintuan L., Zhao N., Le Beau M.M.

Genomics 70:123-130(2000) · UniProtKB (3)

Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene.

Lai F., Orelli B.J., Till B.G., Godley L.A., Fernald A.A., Pamintuan L., Le Beau M.M.

Genomics 66:65-75(2000) · UniProtKB (1)

TTID: a novel gene at 5q31 encoding a protein with titin-like features.

Godley L.A., Lai F., Liu J., Zhao N., Le Beau M.M.

Genomics 60:226-233(1999) · UniProtKB (1)

Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.

Jones J.M., Attardi L., Godley L.A., Laucirica R., Medina D., Jacks T., Varmus H.E., Donehower L.A.

Cell Growth Differ. 8:829-838(1997) · Mapped (11)

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys.

Godley L.A., Kopp J.B., Eckhaus M., Paglino J.J., Owens J., Varmus H.E.

Genes Dev. 10:836-850(1996) · Mapped (11)

Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.

Broccoli D., Godley L.A., Donehower L.A., Varmus H.E., de Lange T.

Mol. Cell. Biol. 16:3765-3772(1996) · Mapped (2)

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.

Donehower L.A., Godley L.A., Aldaz C.M., Pyle R., Shi Y.P., Pinkel D., Gray J., Bradley A., Medina D., Varmus H.E.

Genes Dev. 9:882-895(1995) · Mapped (13)

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