| Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity. Gillardon F., Schmid R., Draheim H.
Neuroscience 208:41-48(2012) · Mapped (4) |
| Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells. Schulz C., Paus M., Frey K., Schmid R., Kohl Z., Mennerich D., Winkler J., Gillardon F.
PLoS ONE 6:e20820-e20820(2011) · Mapped (3) |
| ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2. Haebig K., Gloeckner C.J., Miralles M.G., Gillardon F., Schulte C., Riess O., Ueffing M., Biskup S., Bonin M.
PLoS ONE 5:e13762-e13762(2010) · Mapped (19) |
| Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity. Zach S., Felk S., Gillardon F.
PLoS ONE 5:E13191-E13191(2010) · UniProtKB (3) · Mapped (8) |
| Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro. Gillardon F.
Neuroscience 163:533-539(2009) · Mapped (4) |
| Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration? Gillardon F.
J. Neurochem. 110:1514-1522(2009) · Mapped (7) |
| Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins. Schnack C., Danzer K.M., Hengerer B., Gillardon F.
Neuroscience 154:1450-1457(2008) · Mapped (9) |
| Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers. Danzer K.M., Schnack C., Sutcliffe A., Hengerer B., Gillardon F.
J. Neurochem. 103:2401-2407(2007) · Mapped (2) |
| LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity. Jaleel M., Nichols R.J., Deak M., Campbell D.G., Gillardon F., Knebel A., Alessi D.R.
Biochem. J. 405:307-317(2007) · Mapped (4) |
| Aggravation of brain injury after transient focal ischemia in p53-deficient mice. Maeda K., Hata R., Gillardon F., Hossmann K.A.
Brain Res. Mol. Brain Res. 88:54-61(2001) · Mapped (11) |
| Targeted disruption of the bcl-2 gene in mice exacerbates focal ischemic brain injury. Hata R., Gillardon F., Michaelidis T.M., Hossmann K.A.
Metab Brain Dis 14:117-124(1999) · Mapped (3) |
| Alterations in cell death and cell cycle progression in the UV-irradiated epidermis of bcl-2-deficient mice. Gillardon F., Moll I., Meyer M., Michaelidis T.M.
Cell Death Differ. 6:55-60(1999) · Mapped (3) |
| DNA fragmentation and activation of c-Jun in the cerebellum of mutant mice (weaver, Purkinje cell degeneration). Gillardon F., Baurle J., Grusser-Cornehls U., Zimmermann M.
Neuroreport 6:1766-1768(1995) · Mapped (21) |
| Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Gillardon F., Wickert H., Zimmermann M.
Neurosci. Lett. 192:85-88(1995) · Mapped (7) |
| Differential regulation of bcl-2, bax, c-fos, junB, and krox-24 expression in the cerebellum of Purkinje cell degeneration mutant mice. Gillardon F., Baurle J., Wickert H., Grusser-Cornehls U., Zimmermann M.
J. Neurosci. Res. 41:708-715(1995) · Mapped (14) |
