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Ascorbate in aqueous humor augments nitric oxide production by macrophages.

McKenna K.C., Beatty K.M., Scherder R.C., Li F., Liu H., Chen A.F., Ghosh A., Stuehr D.J.

J. Immunol. 190:556-564(2013) · Mapped (2)

NGL-2 regulates input-specific synapse development in CA1 pyramidal neurons.

DeNardo L.A., de Wit J., Otto-Hitt S., Ghosh A.

Neuron 76:762-775(2012) · Mapped (3)

Characterization of zebrafish von Willebrand factor reveals conservation of domain structure, multimerization, and intracellular storage.

Ghosh A., Vo A., Twiss B.K., Kretz C.A., Jozwiak M.A., Montgomery R.R., Shavit J.A.

Adv Hematol 2012:214209-214209(2012) · Mapped (2)

Elfn1 regulates target-specific release probability at CA1-interneuron synapses.

Sylwestrak E.L., Ghosh A.

Science 338:536-540(2012) · UniProtKB (1) · Mapped (3)

Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor alpha: implications for late infantile Batten disease therapy.

Ghosh A., Corbett G.T., Gonzalez F.J., Pahan K.

J. Biol. Chem. 287:38922-38935(2012) · Mapped (12)

The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy.

Wauson E.M., Zaganjor E., Lee A.Y., Guerra M.L., Ghosh A.B., Bookout A.L., Chambers C.P., Jivan A., McGlynn K., Hutchison M.R. et al.

Mol. Cell 47:851-862(2012) · Mapped (3)

Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure.

Ghosh A.K., Venkateswara Rao K., Yadav N.D., Anderson D.D., Gavande N., Huang X., Terzyan S., Tang J.

J. Med. Chem. 55:9195-9207(2012) · Mapped (1)

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.

Hanash A.M., Dudakov J.A., Hua G., O'Connor M.H., Young L.F., Singer N.V., West M.L., Jenq R.R., Holland A.M., Kappel L.W. et al.

Immunity 37:339-350(2012) · Mapped (6)

The role of extracellular signal-related kinase during abdominal aortic aneurysm formation.

Ghosh A., DiMusto P.D., Ehrlichman L.K., Sadiq O., McEvoy B., Futchko J.S., Henke P.K., Eliason J.L., Upchurch G.R. Jr.

J. Am. Coll. Surg. 215:668-680.e1(2012) · Mapped (11)

Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.

Chaki M., Airik R., Ghosh A.K., Giles R.H., Chen R., Slaats G.G., Wang H., Hurd T.W., Zhou W., Cluckey A. et al.

Cell 150:533-548(2012) · UniProtKB (11) · Mapped (10)

Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme.

Ghosh A., Stuehr D.J.

Proc. Natl. Acad. Sci. U.S.A. 109:12998-13003(2012) · Mapped (8)

3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide.

Ghosh A.K., Hurd T., Hildebrandt F.

Am. J. Physiol. Renal Physiol. 303:F1225-9(2012) · Mapped (13)

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair.

Zhou W., Otto E.A., Cluckey A., Airik R., Hurd T.W., Chaki M., Diaz K., Lach F.P., Bennett G.R., Gee H.Y. et al.

Nat. Genet. 44:910-915(2012) · UniProtKB (1) · Mapped (1)

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress.

Ghosh A.P., Klocke B.J., Ballestas M.E., Roth K.A.

PLoS ONE 7:E39586-E39586(2012) · UniProtKB (5) · Mapped (25)

Branching of the p-nitrophenol (PNP) degradation pathway in burkholderia sp. Strain SJ98: Evidences from genetic characterization of PNP gene cluster.

Vikram S., Pandey J., Bhalla N., Pandey G., Ghosh A., Khan F., Jain R.K., Raghava G.P.

AMB Express 2:30-30(2012) · UniProtKB (2)

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

Charrier C., Joshi K., Coutinho-Budd J., Kim J.E., Lambert N., de Marchena J., Jin W.L., Vanderhaeghen P., Ghosh A., Sassa T. et al.

Cell 149:923-935(2012) · UniProtKB (3) · Mapped (3)

The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability.

Singh D.K., Popuri V., Kulikowicz T., Shevelev I., Ghosh A.K., Ramamoorthy M., Rossi M.L., Janscak P., Croteau D.L., Bohr V.A.

Nucleic Acids Res. 40:6632-6648(2012) · Mapped (7)

FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.

O'Sullivan M.L., de Wit J., Savas J.N., Comoletti D., Otto-Hitt S., Yates J.R., Ghosh A.

Neuron 73:903-910(2012) · Mapped (7)

Enteropathogenic Escherichia coli inhibits ileal sodium-dependent bile acid transporter ASBT.

Annaba F., Sarwar Z., Gill R.K., Ghosh A., Saksena S., Borthakur A., Hecht G.A., Dudeja P.K., Alrefai W.A.

Am. J. Physiol. Gastrointest. Liver Physiol. 302:G1216-22(2012) · Mapped (1)

Interleukin-22 drives endogenous thymic regeneration in mice.

Dudakov J.A., Hanash A.M., Jenq R.R., Young L.F., Ghosh A., Singer N.V., West M.L., Smith O.M., Holland A.M., Tsai J.J. et al.

Science 336:91-95(2012) · Mapped (23)

NeuroD2 regulates the development of hippocampal mossy fiber synapses.

Wilke S.A., Hall B.J., Antonios J.K., Denardo L.A., Otto S., Yuan B., Chen F., Robbins E.M., Tiglio K., Williams M.E. et al.

Neural Dev 7:9-9(2012) · Mapped (2)

Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors.

Ghosh A.K., Chapsal B.D., Steffey M., Agniswamy J., Wang Y.F., Amano M., Weber I.T., Mitsuya H.

Bioorg. Med. Chem. Lett. 22:2308-2311(2012) · Mapped (1)

Increased JNK in males compared with females in a rodent model of abdominal aortic aneurysm.

DiMusto P.D., Lu G., Ghosh A., Roelofs K.J., Sadiq O., McEvoy B., Su G., Laser A., Bhamidipati C.M., Ailawadi G. et al.

J. Surg. Res. 176:687-695(2012) · Mapped (10)

Increased PAI-1 in females compared with males is protective for abdominal aortic aneurysm formation in a rodent model.

DiMusto P.D., Lu G., Ghosh A., Roelofs K.J., Su G., Zhao Y., Lau C.L., Sadiq O., McEvoy B., Laser A. et al.

Am. J. Physiol. Heart Circ. Physiol. 302:H1378-86(2012) · Mapped (5)

The Rett syndrome protein MeCP2 regulates synaptic scaling.

Qiu Z., Sylwestrak E.L., Lieberman D.N., Zhang Y., Liu X.Y., Ghosh A.

J. Neurosci. 32:989-994(2012) · Mapped (18)

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