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51
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for author:"Gazdar A.F."
in Literature Citations
| Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. Gandhi J., Zhang J., Xie Y., Soh J., Shigematsu H., Zhang W., Yamamoto H., Peyton M., Girard L., Lockwood W.W. et al. PLoS ONE 4:e4576-e4576(2009) · Mapped (31) |
| MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors. Kubo T., Yamamoto H., Lockwood W.W., Valencia I., Soh J., Peyton M., Jida M., Otani H., Fujii T., Ouchida M. et al. Int. J. Cancer 124:1778-1784(2009) · Mapped (38) |
| Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Shivapurkar N., Stastny V., Okumura N., Girard L., Xie Y., Prinsen C., Thunnissen F.B., Wistuba I.I., Czerniak B., Frenkel E. et al. Cancer Res. 68:7448-7456(2008) · Mapped (2) |
| PIK3CA mutations and copy number gains in human lung cancers. Yamamoto H., Shigematsu H., Nomura M., Lockwood W.W., Sato M., Okumura N., Soh J., Suzuki M., Wistuba I.I., Fong K.M. et al. Cancer Res. 68:6913-6921(2008) · Mapped (6) |
| Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Kwei K.A., Kim Y.H., Girard L., Kao J., Pacyna-Gengelbach M., Salari K., Lee J., Choi Y.L., Sato M., Wang P. et al. Oncogene 27:3635-3640(2008) · Mapped (4) |
| Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer. Suzuki M., Shigematsu H., Nakajima T., Kubo R., Motohashi S., Sekine Y., Shibuya K., Iizasa T., Hiroshima K., Nakatani Y. et al. Clin. Cancer Res. 13:6087-6092(2007) · Mapped (16) |
| Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells. Eckstein N., Servan K., Girard L., Cai D., von Jonquieres G., Jaehde U., Kassack M.U., Gazdar A.F., Minna J.D., Royer H.D. J. Biol. Chem. 283:739-750(2008) · Mapped (17) |
| The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer. Toyooka S., Matsuo K., Shigematsu H., Kosaka T., Tokumo M., Yatabe Y., Ichihara S., Inukai M., Suehisa H., Soh J. et al. Clin. Cancer Res. 13:5763-5768(2007) · Mapped (15) |
| Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Chen Y., De Marco M.A., Graziani I., Gazdar A.F., Strack P.R., Miele L., Bocchetta M. Cancer Res. 67:7954-7959(2007) · Mapped (3) |
| Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized. Padron D., Sato M., Shay J.W., Gazdar A.F., Minna J.D., Roth M.G. Cancer Res. 67:7695-7702(2007) · Mapped (15) |
| Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers. Nomura M., Shigematsu H., Li L., Suzuki M., Takahashi T., Estess P., Siegelman M., Feng Z., Kato H., Marchetti A. et al. PLoS Med. 4:e125-e125(2007) · Mapped (15) |
| Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. Suzuki M., Shigematsu H., Shames D.S., Sunaga N., Takahashi T., Shivapurkar N., Iizasa T., Minna J.D., Fujisawa T., Gazdar A.F. Ann. Surg. Oncol. 14:1397-1404(2007) · Mapped (3) |
| Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Das A.K., Sato M., Story M.D., Peyton M., Graves R., Redpath S., Girard L., Gazdar A.F., Shay J.W., Minna J.D. et al. Cancer Res. 66:9601-9608(2006) · Mapped (15) |
| The consensus coding sequences of human breast and colorectal cancers. Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N. et al. |
| HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Wang S.E., Narasanna A., Perez-Torres M., Xiang B., Wu F.Y., Yang S., Carpenter G., Gazdar A.F., Muthuswamy S.K., Arteaga C.L. Cancer Cell 10:25-38(2006) · Mapped (8) |
| Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Tam I.Y.S., Chung L.P., Suen W.S., Wang E., Wong M.C.M., Ho K.K., Lam W.K., Chiu S.W., Girard L., Minna J.D. et al. Clin. Cancer Res. 12:1647-1653(2006) · UniProtKB (2) · Mapped (14) |
| DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers. Suzuki M., Shigematsu H., Shames D.S., Sunaga N., Takahashi T., Shivapurkar N., Iizasa T., Frenkel E.P., Minna J.D., Fujisawa T. et al. Br. J. Cancer 93:1029-1037(2005) · Mapped (9) |
| Epidermal growth factor receptor expression status in lung cancer correlates with its mutation. Suzuki M., Shigematsu H., Hiroshima K., Iizasa T., Nakatani Y., Minna J.D., Gazdar A.F., Fujisawa T. Hum. Pathol. 36:1127-1134(2005) · Mapped (15) |
| Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas. Heller G., Fong K.M., Girard L., Seidl S., End-Pfutzenreuter A., Lang G., Gazdar A.F., Minna J.D., Zielinski C.C., Zochbauer-Muller S. Oncogene 25:959-968(2006) · Mapped (4) |
| TP53 abnormalities are frequent and early events in the sequential pathogenesis of gallbladder carcinoma. Moreno M., Pimentel F., Gazdar A.F., Wistuba I.I., Miquel J.F. Ann Hepatol 4:192-199(2005) · Mapped (31) |
| Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro. Haruki N., Kawaguchi K.S., Eichenberger S., Massion P.P., Gonzalez A., Gazdar A.F., Minna J.D., Carbone D.P., Dang T.P. J. Med. Genet. 42:558-564(2005) · Mapped (10) |
| Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation. Zochbauer-Muller S., Fong K.M., Geradts J., Xu X., Seidl S., End-Pfutzenreuter A., Lang G., Heller G., Zielinski C.C., Gazdar A.F. et al. Oncogene 24:6249-6255(2005) · Mapped (1) |
| Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. Shigematsu H., Lin L., Takahashi T., Nomura M., Suzuki M., Wistuba I.I., Fong K.M., Lee H., Toyooka S., Shimizu N. et al. J. Natl. Cancer Inst. 97:339-346(2005) · Mapped (23) |
| The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer. Sekine I., Sato M., Sunaga N., Toyooka S., Peyton M., Parsons R., Wang W., Gazdar A.F., Minna J.D. |
| The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers. Tokumo M., Toyooka S., Kiura K., Shigematsu H., Tomii K., Aoe M., Ichimura K., Tsuda T., Yano M., Tsukuda K. et al. Clin. Cancer Res. 11:1167-1173(2005) · Mapped (15) |
