1 - 25 of 48 results for author:"Freemont P.S." in Literature citations
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| Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Lu D., Silhan J., MacDonald J.T., Carpenter E.P., Jensen K., Tang C.M., Baldwin G.S., Freemont P.S. Proc. Natl. Acad. Sci. U.S.A. 109:16852-16857(2012) · UniProtKB (1) |
| The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP. Niwa H., Ewens C.A., Tsang C., Yeung H.O., Zhang X., Freemont P.S. J. Biol. Chem. 287:8561-8570(2012) · Mapped (6) |
| A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. Heathcote D.A., Patel H., Kroll S.H., Hazel P., Periyasamy M., Alikian M., Kanneganti S.K., Jogalekar A.S., Scheiper B., Barbazanges M. et al. J. Med. Chem. 53:8508-8522(2010) · Mapped (1) |
| Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. Lu D., Wormann M.E., Zhang X., Schneewind O., Grundling A., Freemont P.S. Proc. Natl. Acad. Sci. U.S.A. 106:1584-1589(2009) · UniProtKB (1) |
| Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase. Briggs L.C., Baldwin G.S., Miyata N., Kondo H., Zhang X., Freemont P.S. J. Biol. Chem. 283:13745-13752(2008) · Mapped (2) |
| Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low-density lipoproteins. Martin C.A., Longman E., Wooding C., Hoosdally S.J., Ali S., Aitman T.J., Gutmann D.A., Freemont P.S., Byrne B., Linton K.J. Protein Sci. 16:2531-2541(2007) · Mapped (19) |
| Detailed structural insights into the p97-Npl4-Ufd1 interface. Isaacson R.L., Pye V.E., Simpson P., Meyer H.H., Zhang X., Freemont P.S., Matthews S. J. Biol. Chem. 282:21361-21369(2007) · Mapped (9) |
| Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity. Muzzolini L., Beuron F., Patwardhan A., Popuri V., Cui S., Niccolini B., Rappas M., Freemont P.S., Vindigni A. PLoS Biol. 5:e20-e20(2007) · Mapped (1) |
| The transcriptional regulator CBP has defined spatial associations within interphase nuclei. McManus K.J., Stephens D.A., Adams N.M., Islam S.A., Freemont P.S., Hendzel M.J. PLoS Comput. Biol. 2:e139-e139(2006) · Mapped (5) |
| Conformational changes in the AAA ATPase p97-p47 adaptor complex. Beuron F., Dreveny I., Yuan X., Pye V.E., McKeown C., Briggs L.C., Cliff M.J., Kaneko Y., Wallis R., Isaacson R.L. et al. EMBO J. 25:1967-1976(2006) · Mapped (2) |
| Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. Dreveny I., Kondo H., Uchiyama K., Shaw A., Zhang X., Freemont P.S. |
| Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions. Wang J., Shiels C., Sasieni P., Wu P.J., Islam S.A., Freemont P.S., Sheer D. J. Cell Biol. 164:515-526(2004) · Mapped (10) |
| The crystal structure of murine p97/VCP at 3.6A. Huyton T., Pye V.E., Briggs L.C., Flynn T.C., Beuron F., Kondo H., Ma J., Zhang X., Freemont P.S. J. Struct. Biol. 144:337-348(2003) · UniProtKB (1) · Mapped (1) |
| Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders. Jones B., Jones E.L., Bonney S.A., Patel H.N., Mensenkamp A.R., Eichenbaum-Voline S., Rudling M., Myrdal U., Annesi G., Naik S. et al. |
| Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9. Tan K., Shaw A.L., Madsen B., Jensen K., Taylor-Papadimitriou J., Freemont P.S. J. Biol. Chem. 278:20507-20513(2003) · UniProtKB (3) · Mapped (15) |
| PML protein isoforms and the RBCC/TRIM motif. Jensen K., Shiels C., Freemont P.S. Oncogene 20:7223-7233(2001) · UniProtKB (1) |
| High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding. Morera S., Lariviere L., Kurzeck J., Aschke-Sonnenborn U., Freemont P.S., Janin J., Ruger W. J. Mol. Biol. 311:569-577(2001) · Mapped (1) |
| Solution structure and interaction surface of the C-terminal domain from p47: a major p97-cofactor involved in SNARE disassembly. Yuan X., Shaw A., Zhang X., Kondo H., Lally J., Freemont P.S., Matthews S. J. Mol. Biol. 311:255-263(2001) · UniProtKB (1) |
| Structure of the AAA ATPase p97. Zhang X., Shaw A., Bates P.A., Newman R.H., Gowen B., Orlova E., Gorman M.A., Kondo H., Dokurno P., Lally J. et al. |
| HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. Bardos J.I., Saurin A.J., Tissot C., Duprez E., Freemont P.S. J. Biol. Chem. 275:28785-28792(2000) · UniProtKB (1) |
| Role of SUMO-1-modified PML in nuclear body formation. Zhong S., Muller S., Ronchetti S., Freemont P.S., Dejean A., Pandolfi P.P. |
| T4 phage beta-glucosyltransferase: substrate binding and proposed catalytic mechanism. Morera S., Imberty A., Aschke-Sonnenborn U., Ruger W., Freemont P.S. J. Mol. Biol. 292:717-730(1999) · UniProtKB (1) |
| Oligomeric ring structure of the Bloom's syndrome helicase. Karow J.K., Newman R.H., Freemont P.S., Hickson I.D. Curr. Biol. 9:597-600(1999) |
| SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation. Duprez E., Saurin A.J., Desterro J.M., Lallemand-Breitenbach V., Howe K., Boddy M.N., Solomon E., de The H., Hay R.T., Freemont P.S. J. Cell. Sci. 112:381-393(1999) |
| Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. Zhang X., Morera S., Bates P.A., Whitehead P.C., Coffer A.I., Hainbucher K., Nash R.A., Sternberg M.J., Lindahl T., Freemont P.S. EMBO J. 17:6404-6411(1998) · Mapped (1) |