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Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly.

Verhelst J., Parthoens E., Schepens B., Fiers W., Saelens X.

J. Virol. 86:13445-13455(2012) · Mapped (2)

Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection.

El Bakkouri K., Descamps F., De Filette M., Smet A., Festjens E., Birkett A., Van Rooijen N., Verbeek S., Fiers W., Saelens X.

J. Immunol. 186:1022-1031(2011) · Mapped (10)

Two tumour necrosis factor receptors: structure and function.

Vandenabeele P., Declercq W., Beyaert R., Fiers W.

Trends Cell Biol. 5:392-399(1995) · Mapped (12)

Expression in Escherichia coli of the death domain of the human p55 tumor necrosis factor receptor.

De Wilde G., Mertens N., Boone E., De Vreese B., Van Beeumen J., Fiers W., Haegeman G.

Protein Expr. Purif. 23:226-232(2001) · Mapped (4)

Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase.

Cauwels A., Van Molle W., Janssen B., Everaerdt B., Huang P., Fiers W., Brouckaert P.

Immunity 13:223-231(2000) · Mapped (5)

The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.

de Valck D., Jin D.-Y., Heyninck K., van de Craen M., Contreras R., Fiers W., Jeang K.-T., Beyaert R.

Oncogene 18:4182-4190(1999) · UniProtKB (3) · Mapped (3)

The zinc finger protein A20 inhibits TNF-induced NF-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-B-inhibiting protein ABIN.

Heyninck K., De Valck D., Vanden Berghe W., Van Criekinge W., Contreras R., Fiers W., Haegeman G., Beyaert R.

J. Cell Biol. 145:1471-1482(1999) · UniProtKB (2) · Mapped (13)

GAL4 is a substrate for caspases: implications for two-hybrid screening and other GAL4-based assays.

van Criekinge W., Cornelis S., Van De Craen M., Vandenabeele P., Fiers W., Beyaert R.

Mol. Cell Biol. Res. Commun. 1:158-161(1999) · Mapped (1)

Identification of a new caspase homologue: caspase-14.

Van de Craen M., Van Loo G., Pype S., Van Criekinge W., Van den brande I., Molemans F., Fiers W., Declercq W., Vandenabeele P.

Cell Death Differ. 5:838-846(1998) · UniProtKB (1)

The structure of mouse tumour-necrosis factor at 1.4 A resolution: towards modulation of its selectivity and trimerization.

Baeyens K.J., De Bondt H.L., Raeymaekers A., Fiers W., De Ranter C.J.

Acta Crystallogr. D 55:772-778(1999) · UniProtKB (1)

Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock.

Libert C., Wielockx B., Hammond G.L., Brouckaert P., Fiers W., Elliott R.W.

Genomics 55:284-289(1999) · Mapped (5)

Molecular cloning and identification of murine caspase-8.

Van de Craen M., Van Loo G., Declercq W., Schotte P., van den Brande I., Mandruzzato S., van der Bruggen P., Fiers W., Vandenabeele P.

J. Mol. Biol. 284:1017-1026(1998) · UniProtKB (1) · Mapped (15)

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

Vercammen D., Beyaert R., Denecker G., Goossens V., Van Loo G., Declercq W., Grooten J., Fiers W., Vandenabeele P.

J. Exp. Med. 187:1477-1485(1998) · Mapped (7)

A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins.

De Valck D., Heyninck K., Van Criekinge W., Vandenabeele P., Fiers W., Beyaert R.

Biochem. Biophys. Res. Commun. 238:590-594(1997) · UniProtKB (1) · Mapped (2)

Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.

Lucas R., Juillard P., Decoster E., Redard M., Burger D., Donati Y., Giroud C., Monso-Hinard C., De Kesel T., Buurman W.A. et al.

Eur. J. Immunol. 27:1719-1725(1997) · Mapped (14)

Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal.

Barge R.M., Willemze R., Vandenabeele P., Fiers W., Beyaert R.

FEBS Lett. 409:207-210(1997) · Mapped (11)

Characterization of seven murine caspase family members.

van de Craen M., Vandenabeele P., Declercq W., van den Brande I., van Loo G., Molemans F., Schotte P., van Criekinge W., Beyaert R., Fiers W.

FEBS Lett. 403:61-69(1997) · UniProtKB (7) · Mapped (17)

Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) production during murine endotoxaemia.

Marchant A., Amraoui Z., Gueydan C., Bruyns C., Le Moine O., Vandenabeele P., Fiers W., Buurman W.A., Goldman M.

Clin. Exp. Immunol. 106:91-96(1996) · Mapped (6)

A20, an inhibitor of cell death, self-associates by its zinc finger domain.

De Valck D., Heyninck K., Van Criekinge W., Contreras R., Beyaert R., Fiers W.

FEBS Lett. 384:61-64(1996)

ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines.

Lassalle P., Molet S., Janin A., Vander-Heyden J.E., Tavernier J., Fiers W., Devos R.E., Tonnel A.-B.

J. Biol. Chem. 271:20458-20464(1996) · UniProtKB (1)

Recombinant IL-1 receptor antagonist protects against TNF-induced lethality in mice.

Everaerdt B., Brouckaert P., Fiers W.

J. Immunol. 152:5041-5049(1994) · Mapped (10)

Molecular mechanisms of tumor necrosis factor-induced cytotoxicity. What we do understand and what we do not.

Beyaert R., Fiers W.

FEBS Lett. 340:9-16(1994) · Mapped (4)

The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp70 stress protein genes SSA3 and SSA4.

Logghe M., Molemans F., Fiers W., Contreras R.

Yeast 10:1093-1100(1994) · UniProtKB (5) · Mapped (1)

Protection by alpha 1-acid glycoprotein against tumor necrosis factor-induced lethality.

Libert C., Brouckaert P., Fiers W.

J. Exp. Med. 180:1571-1575(1994) · Mapped (7)

Complete DNA sequence of yeast chromosome II.

Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E. et al.

EMBO J. 13:5795-5809(1994) · UniProtKB (461) · Mapped (1)

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