1 - 25 of 42 results for author:"Fernandes-Alnemri T." in Literature citations
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| Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection. Fang R., Tsuchiya K., Kawamura I., Shen Y., Hara H., Sakai S., Yamamoto T., Fernandes-Alnemri T., Yang R., Hernandez-Cuellar E. et al. J. Immunol. 187:4890-4899(2011) · Mapped (6) |
| Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes. Wu J., Fernandes-Alnemri T., Alnemri E.S. J. Clin. Immunol. 30:693-702(2010) · Mapped (2) |
| The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Fernandes-Alnemri T., Yu J.W., Juliana C., Solorzano L., Kang S., Wu J., Datta P., McCormick M., Huang L., McDermott E. et al. |
| Functional consequences of a germline mutation in the leucine-rich repeat domain of NLRP3 identified in an atypical autoinflammatory disorder. Jeru I., Marlin S., Le Borgne G., Cochet E., Normand S., Duquesnoy P., Dastot-Le Moal F., Cuisset L., Hentgen V., Fernandes Alnemri T. et al. Arthritis Rheum. 62:1176-1185(2010) · Mapped (4) |
| Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. Bauernfeind F.G., Horvath G., Stutz A., Alnemri E.S., MacDonald K., Speert D., Fernandes-Alnemri T., Wu J., Monks B.G., Fitzgerald K.A. et al. J. Immunol. 183:787-791(2009) · Mapped (52) |
| AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Fernandes-Alnemri T., Yu J.W., Datta P., Wu J., Alnemri E.S. |
| The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila. Khan F.S., Fujioka M., Datta P., Fernandes-Alnemri T., Jaynes J.B., Alnemri E.S. Cell Death Differ. 15:1073-1083(2008) · UniProtKB (2) · Mapped (4) |
| Mutations in NALP12 cause hereditary periodic fever syndromes. Jeru I., Duquesnoy P., Fernandes-Alnemri T., Cochet E., Yu J.W., Lackmy-Port-Lis M., Grimprel E., Landman-Parker J., Hentgen V., Marlin S. et al. Proc. Natl. Acad. Sci. U.S.A. 105:1614-1619(2008) · UniProtKB (1) · Mapped (3) |
| Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. Yu J.W., Fernandes-Alnemri T., Datta P., Wu J., Juliana C., Solorzano L., McCormick M., Zhang Z., Alnemri E.S. Mol. Cell 28:214-227(2007) · Mapped (10) |
| The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Fernandes-Alnemri T., Wu J., Yu J.W., Datta P., Miller B., Jankowski W., Rosenberg S., Zhang J., Alnemri E.S. Cell Death Differ. 14:1590-1604(2007) · UniProtKB (1) · Mapped (1) |
| Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. Yu J.W., Wu J., Zhang Z., Datta P., Ibrahimi I., Taniguchi S., Sagara J., Fernandes-Alnemri T., Alnemri E.S. Cell Death Differ. 13:236-249(2006) · UniProtKB (1) · Mapped (18) |
| The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity. Gupta S., Singh R., Datta P., Zhang Z., Orr C., Lu Z., Dubois G., Zervos A.S., Meisler M.H., Srinivasula S.M. et al. J. Biol. Chem. 279:45844-45854(2004) · Mapped (2) |
| Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death. Guo Y., Cheong N., Zhang Z., De Rose R., Deng Y., Farber S.A., Fernandes-Alnemri T., Alnemri E.S. J. Biol. Chem. 279:24813-24825(2004) · UniProtKB (4) · Mapped (14) |
| Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Jones J.M., Datta P., Srinivasula S.M., Ji W., Gupta S., Zhang Z., Davies E., Hajnoczky G., Saunders T.L., Van Keuren M.L. et al. Nature 425:721-727(2003) · Mapped (10) |
| The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein. Hegde R., Srinivasula S.M., Datta P., Madesh M., Wassell R., Zhang Z., Cheong N., Nejmeh J., Fernandes-Alnemri T., Hoshino S. et al. J. Biol. Chem. 278:38699-38706(2003) · Mapped (7) |
| Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2. Srinivasula S.M., Gupta S., Datta P., Zhang Z., Hegde R., Cheong N., Fernandes-Alnemri T., Alnemri E.S. J. Biol. Chem. 278:31469-31472(2003) · Mapped (6) |
| Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC. Zhan Y., Hegde R., Srinivasula S.M., Fernandes-Alnemri T., Alnemri E.S. Cell Death Differ. 9:439-447(2002) · UniProtKB (3) · Mapped (1) |
| Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. Guo Y., Srinivasula S.M., Druilhe A., Fernandes-Alnemri T., Alnemri E.S. J. Biol. Chem. 277:13430-13437(2002) · Mapped (7) |
| sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Srinivasula S.M., Datta P., Kobayashi M., Wu J.W., Fujioka M., Hegde R., Zhang Z., Mukattash R., Fernandes-Alnemri T., Shi Y. et al. |
| Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. Poyet J.-L., Srinivasula S.M., Tnani M., Razmara M., Fernandes-Alnemri T., Alnemri E.S. J. Biol. Chem. 276:28309-28313(2001) · UniProtKB (1) · Mapped (1) |
| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Srinivasula S.M., Hegde R., Saleh A., Datta P., Shiozaki E., Chai J., Lee R.A., Robbins P.D., Fernandes-Alnemri T., Shi Y. et al. Nature 410:112-116(2001) · Mapped (2) |
| Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. Srinivasula S.M., Datta P., Fan X.J., Fernandes-Alnemri T., Huang Z., Alnemri E.S. J. Biol. Chem. 275:36152-36157(2000) · UniProtKB (1) |
| Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Qin H., Srinivasula S.M., Wu G., Fernandes-Alnemri T., Alnemri E.S., Shi Y. Nature 399:549-557(1999) · Mapped (2) |
| CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis. Srinivasula S.M., Ahmad M., Lin J.-H., Poyet J.-L., Fernandes-Alnemri T., Tsichlis P.N., Alnemri E.S. J. Biol. Chem. 274:17946-17954(1999) · UniProtKB (3) · Mapped (2) |
| Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Srinivasula S.M., Ahmad M., Guo Y., Zhan Y., Lazebnik Y., Fernandes-Alnemri T., Alnemri E.S. Cancer Res. 59:999-1002(1999) · UniProtKB (1) |