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Distinct ribosome maturation defects in yeast models of Diamond Blackfan anemia and Shwachman Diamond syndrome.

Moore J.B., Farrar J.E., Arceci R.J., Liu J.M., Ellis S.R.

Haematologica 0:0-0(2009) · Mapped (2)

Glucose-6-phosphate dehydrogenase (G6PD) mutations and haemoglobinuria syndrome in the Vietnamese population.

Hue N.T., Charlieu J.P., Chau T.T., Day N., Farrar J.J., Hien T.T., Dunstan S.J.

Malar. J. 8:152-152(2009) · Mapped (8)

Reciprocal responsiveness to interleukin-12 and interferon-alpha specifies human CD8+ effector versus central memory T-cell fates.

Ramos H.J., Davis A.M., Cole A.G., Schatzle J.D., Forman J., Farrar J.D.

Blood 113:5516-5525(2009) · Mapped (3)

Toll-like receptor 4 (TLR4) and typhoid fever in Vietnam.

Nguyen T.H., Mai N.L., Le T.P., Ha V., Nguyen T.C., Tran T.H., Nguyen T.H., Farrar J.J., Dunstan S.J.

PLoS ONE 4:e4800-e4800(2009) · Mapped (1)

Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.

Thuong N.T., Dunstan S.J., Chau T.T., Thorsson V., Simmons C.P., Quyen N.T., Thwaites G.E., Thi Ngoc Lan N., Hibberd M., Teo Y.Y. et al.

PLoS Pathog. 4:e1000229-e1000229(2008) · Mapped (2)

Cutting edge: a T-bet-independent role for IFN-alpha/beta in regulating IL-2 secretion in human CD4+ central memory T cells.

Davis A.M., Ramos H.J., Davis L.S., Farrar J.D.

J. Immunol. 181:8204-8208(2008) · Mapped (5)

Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts.

Suzuki T., Farrar J.E., Yegnasubramanian S., Zahed M., Suzuki N., Arceci R.J.

Epigenetics 3:281-291(2008) · Mapped (6)

Me Tri virus: a Semliki Forest virus strain from Vietnam?

Tan l.e. V., Ha d.o. Q., Hien V.M., van der Hoek L., Farrar J., de Jong M.D.

J. Gen. Virol. 89:2132-2135(2008) · UniProtKB (2)

The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions.

Young J.A., Becker A.M., Medeiros J.J., Shapiro V.S., Wang A., Farrar J.D., Quill T.A., Hooft van Huijsduijnen R., van Oers N.S.

Mol. Immunol. 45:3756-3766(2008) · Mapped (13)

Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia.

Farrar J.E., Nater M., Caywood E., McDevitt M.A., Kowalski J., Takemoto C.M., Talbot C.C. Jr., Meltzer P., Esposito D., Beggs A.H. et al.

Blood 112:1582-1592(2008) · UniProtKB (1)

The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis.

Caws M., Thwaites G., Dunstan S., Hawn T.R., Lan N.T., Thuong N.T., Stepniewska K., Huyen M.N., Bang N.D., Loc T.H. et al.

PLoS Pathog. 4:e1000034-e1000034(2008) · Mapped (4)

Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones.

Chau T.T., Campbell J.I., Galindo C.M., Van Minh Hoang N., Diep T.S., Nga T.T., Van Vinh Chau N., Tuan P.Q., Page A.L., Ochiai R.L. et al.

Antimicrob. Agents Chemother. 51:4315-4323(2007) · UniProtKB (2)

IFN-alpha is not sufficient to drive Th1 development due to lack of stable T-bet expression.

Ramos H.J., Davis A.M., George T.C., Farrar J.D.

J. Immunol. 179:3792-3803(2007) · Mapped (1)

The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.

Zhang L., Anglesio M.S., O'Sullivan M., Zhang F., Yang G., Sarao R., Mai P.N., Cronin S., Hara H., Melnyk N. et al.

Nat. Med. 13:1060-1069(2007) · Mapped (22)

A common human TLR1 polymorphism regulates the innate immune response to lipopeptides.

Hawn T.R., Misch E.A., Dunstan S.J., Thwaites G.E., Lan N.T., Quy H.T., Chau T.T., Rodrigues S., Nachman A., Janer M. et al.

Eur. J. Immunol. 37:2280-2289(2007) · Mapped (5)

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis.

Thuong N.T., Hawn T.R., Thwaites G.E., Chau T.T., Lan N.T., Quy H.T., Hieu N.T., Aderem A., Hien T.T., Farrar J.J. et al.

Genes Immun. 8:422-428(2007) · Mapped (2)

A TNF region haplotype offers protection from typhoid fever in Vietnamese patients.

Dunstan S.J., Nguyen T.H., Rockett K., Forton J., Morris A.P., Diakite M., Mai N.L., Le T.P., House D., Parry C.M. et al.

Hum. Genet. 122:51-61(2007) · Mapped (6)

Cerebral calpain in fatal falciparum malaria.

Medana I.M., Day N.P., Hien T.T., Mai N.T., Bethell D., Phu N.H., Turner G.D., Farrar J., White N.J., Esiri M.M.

Neuropathol. Appl. Neurobiol. 33:179-192(2007) · Mapped (11)

Evolutionary history of Salmonella typhi.

Roumagnac P., Weill F.X., Dolecek C., Baker S., Brisse S., Chinh N.T., Le T.A., Acosta C.J., Farrar J., Dougan G. et al.

Science 314:1301-1304(2006) · UniProtKB (93)

Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain.

Tyler D.R., Persky M.E., Matthews L.A., Chan S., Farrar J.D.

Mol. Immunol. 44:1864-1872(2007) · Mapped (11)

Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha.

Berenson L.S., Gavrieli M., Farrar J.D., Murphy T.L., Murphy K.M.

J. Immunol. 177:5195-5203(2006) · Mapped (20)

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis.

Hawn T.R., Dunstan S.J., Thwaites G.E., Simmons C.P., Thuong N.T., Lan N.T., Quy H.T., Chau T.T., Hieu N.T., Rodrigues S. et al.

J. Infect. Dis. 194:1127-1134(2006) · Mapped (2)

Polymorphisms of the gene coding for copper/zinc superoxide dismutase (SOD1) in patients with Japanese encephalitis.

Thuong N.T., Dunstan S.J., Dung N.M., Charlieu J.P., Loan H.T., Wills B., Solomon T., Farrar J.J.

Ann Trop Med Parasitol 100:631-636(2006) · Mapped (1)

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia.

de Jong M.D., Simmons C.P., Thanh T.T., Hien V.M., Smith G.J., Chau T.N., Hoang D.M., Chau N.V., Khanh T.H., Dong V.C. et al.

Nat. Med. 12:1203-1207(2006) · UniProtKB (10)

Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam.

Smith G.J., Naipospos T.S., Nguyen T.D., de Jong M.D., Vijaykrishna D., Usman T.B., Hassan S.S., Nguyen T.V., Dao T.V., Bui N.A. et al.

Virology 350:258-268(2006) · UniProtKB (875)

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