1 - 25 of 102 results for author:"Farese R.V." in Literature citations
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| Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases. Eichmann T.O., Kumari M., Haas J.T., Farese R.V. Jr., Zimmermann R., Lass A., Zechner R. J. Biol. Chem. 287:41446-41457(2012) · Mapped (7) |
| Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. Martens L.H., Zhang J., Barmada S.J., Zhou P., Kamiya S., Sun B., Min S.W., Gan L., Finkbeiner S., Huang E.J. et al. J. Clin. Invest. 122:3955-3959(2012) · Mapped (18) |
| The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. Xu N., Zhang S.O., Cole R.A., McKinney S.A., Guo F., Haas J.T., Bobba S., Farese R.V. Jr., Mak H.Y. J. Cell Biol. 198:895-911(2012) · Mapped (9) |
| Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Haas J.T., Miao J., Chanda D., Wang Y., Zhao E., Haas M.E., Hirschey M., Vaitheesvaran B., Farese R.V. Jr., Kurland I.J. et al. Cell Metab. 15:873-884(2012) · Mapped (5) |
| Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood. Zhang J., Kelley K.L., Marshall S.M., Davis M.A., Wilson M.D., Sawyer J.K., Farese R.V. Jr., Brown J.M., Rudel L.L. J. Lipid Res. 53:1144-1152(2012) · Mapped (4) |
| Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. Harris C., Herker E., Farese R.V. Jr., Ott M. J. Biol. Chem. 286:42615-42625(2011) · Mapped (154) |
| Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Krahmer N., Guo Y., Wilfling F., Hilger M., Lingrell S., Heger K., Newman H.W., Schmidt-Supprian M., Vance D.E., Mann M. et al. Cell Metab. 14:504-515(2011) · Mapped (5) |
| Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Rosen E.Y., Wexler E.M., Versano R., Coppola G., Gao F., Winden K.D., Oldham M.C., Martens L.H., Zhou P., Farese R.V. Jr. et al. Neuron 71:1030-1042(2011) · Mapped (21) |
| SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Hirschey M.D., Shimazu T., Jing E., Grueter C.A., Collins A.M., Aouizerat B., Stancakova A., Goetzman E., Lam M.M., Schwer B. et al. Mol. Cell 44:177-190(2011) · Mapped (10) |
| A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Kao A.W., Eisenhut R.J., Martens L.H., Nakamura A., Huang A., Bagley J.A., Zhou P., de Luis A., Neukomm L.J., Cabello J. et al. Proc. Natl. Acad. Sci. U.S.A. 108:4441-4446(2011) · Mapped (20) |
| DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. Harris C.A., Haas J.T., Streeper R.S., Stone S.J., Kumari M., Yang K., Han X., Brownell N., Gross R.W., Zechner R. et al. J. Lipid Res. 52:657-667(2011) · Mapped (8) |
| Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Herker E., Harris C., Hernandez C., Carpentier A., Kaehlcke K., Rosenberg A.R., Farese R.V. Jr., Ott M. Nat. Med. 16:1295-1298(2010) · Mapped (2) |
| SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Hirschey M.D., Shimazu T., Goetzman E., Jing E., Schwer B., Lombard D.B., Grueter C.A., Harris C., Biddinger S., Ilkayeva O.R. et al. Nature 464:121-125(2010) · Mapped (8) |
| Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation. Sopasakis V.R., Liu P., Suzuki R., Kondo T., Winnay J., Tran T.T., Asano T., Smyth G., Sajan M.P., Farese R.V. et al. Cell Metab. 11:220-230(2010) · Mapped (2) |
| DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation. Koliwad S.K., Streeper R.S., Monetti M., Cornelissen I., Chan L., Terayama K., Naylor S., Rao M., Hubbard B., Farese R.V. Jr. J. Clin. Invest. 120:756-767(2010) · Mapped (7) |
| AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC. Sajan M.P., Bandyopadhyay G., Miura A., Standaert M.L., Nimal S., Longnus S.L., Van Obberghen E., Hainault I., Foufelle F., Kahn R. et al. Am. J. Physiol. Endocrinol. Metab. 298:E179-92(2010) · Mapped (7) |
| Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses. Thaler J.P., Choi S.J., Sajan M.P., Ogimoto K., Nguyen H.T., Matsen M., Benoit S.C., Wisse B.E., Farese R.V., Schwartz M.W. Endocrinology 150:5362-5372(2009) · Mapped (3) |
| Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. Koliwad S.K., Kuo T., Shipp L.E., Gray N.E., Backhed F., So A.Y., Farese R.V. Jr., Wang J.C. J. Biol. Chem. 284:25593-25601(2009) · Mapped (24) |
| The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis. Guo S., Copps K.D., Dong X., Park S., Cheng Z., Pocai A., Rossetti L., Sajan M., Farese R.V., White M.F. Mol. Cell. Biol. 29:5070-5083(2009) · Mapped (5) |
| Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance. Sajan M.P., Standaert M.L., Rivas J., Miura A., Kanoh Y., Soto J., Taniguchi C.M., Kahn C.R., Farese R.V. Diabetologia 52:1197-1207(2009) · Mapped (10) |
| Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Yen C.L., Cheong M.L., Grueter C., Zhou P., Moriwaki J., Wong J.S., Hubbard B., Marmor S., Farese R.V. Jr. Nat. Med. 15:442-446(2009) · Mapped (1) |
| The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity. Sajan M.P., Standaert M.L., Nimal S., Varanasi U., Pastoor T., Mastorides S., Braun U., Leitges M., Farese R.V. J. Lipid Res. 50:1133-1145(2009) · Mapped (7) |
| The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. Stone S.J., Levin M.C., Zhou P., Han J., Walther T.C., Farese R.V. Jr. J. Biol. Chem. 284:5352-5361(2009) · Mapped (6) |
| Retinol esterification by DGAT1 is essential for retinoid homeostasis in murine skin. Shih M.Y., Kane M.A., Zhou P., Yen C.L., Streeper R.S., Napoli J.L., Farese R.V. Jr. J. Biol. Chem. 284:4292-4299(2009) · UniProtKB (1) · Mapped (3) |
| Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle. Temofonte N., Sajan M.P., Nimal S., Pastoor T., Fumero C., Casaubon L., Powe J.L., Standaert M.L., Farese R.V. Diabetologia 52:60-64(2009) · Mapped (7) |