1 - 25 of 74 results for author:"Farese R.V. Jr." in Literature citations
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| DGAT1 mutation is linked to a congenital diarrheal disorder. Haas J.T., Winter H.S., Lim E., Kirby A., Blumenstiel B., DeFelice M., Gabriel S., Jalas C., Branski D., Grueter C.A. et al. J. Clin. Invest. 122:4680-4684(2012) · Mapped (2) |
| Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases. Eichmann T.O., Kumari M., Haas J.T., Farese R.V. Jr., Zimmermann R., Lass A., Zechner R. J. Biol. Chem. 287:41446-41457(2012) · Mapped (12) |
| Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. Martens L.H., Zhang J., Barmada S.J., Zhou P., Kamiya S., Sun B., Min S.W., Gan L., Finkbeiner S., Huang E.J. et al. J. Clin. Invest. 122:3955-3959(2012) · Mapped (18) |
| The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. Xu N., Zhang S.O., Cole R.A., McKinney S.A., Guo F., Haas J.T., Bobba S., Farese R.V. Jr., Mak H.Y. J. Cell Biol. 198:895-911(2012) · Mapped (9) |
| Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Haas J.T., Miao J., Chanda D., Wang Y., Zhao E., Haas M.E., Hirschey M., Vaitheesvaran B., Farese R.V. Jr., Kurland I.J. et al. Cell Metab. 15:873-884(2012) · Mapped (5) |
| Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood. Zhang J., Kelley K.L., Marshall S.M., Davis M.A., Wilson M.D., Sawyer J.K., Farese R.V. Jr., Brown J.M., Rudel L.L. J. Lipid Res. 53:1144-1152(2012) · Mapped (4) |
| Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. Harris C., Herker E., Farese R.V. Jr., Ott M. J. Biol. Chem. 286:42615-42625(2011) · Mapped (1) |
| Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Krahmer N., Guo Y., Wilfling F., Hilger M., Lingrell S., Heger K., Newman H.W., Schmidt-Supprian M., Vance D.E., Mann M. et al. Cell Metab. 14:504-515(2011) · Mapped (5) |
| Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Rosen E.Y., Wexler E.M., Versano R., Coppola G., Gao F., Winden K.D., Oldham M.C., Martens L.H., Zhou P., Farese R.V. Jr. et al. Neuron 71:1030-1042(2011) · Mapped (20) |
| SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Hirschey M.D., Shimazu T., Jing E., Grueter C.A., Collins A.M., Aouizerat B., Stancakova A., Goetzman E., Lam M.M., Schwer B. et al. Mol. Cell 44:177-190(2011) · Mapped (10) |
| A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Kao A.W., Eisenhut R.J., Martens L.H., Nakamura A., Huang A., Bagley J.A., Zhou P., de Luis A., Neukomm L.J., Cabello J. et al. Proc. Natl. Acad. Sci. U.S.A. 108:4441-4446(2011) · Mapped (20) |
| DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. Harris C.A., Haas J.T., Streeper R.S., Stone S.J., Kumari M., Yang K., Han X., Brownell N., Gross R.W., Zechner R. et al. J. Lipid Res. 52:657-667(2011) · Mapped (8) |
| Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Herker E., Harris C., Hernandez C., Carpentier A., Kaehlcke K., Rosenberg A.R., Farese R.V. Jr., Ott M. Nat. Med. 16:1295-1298(2010) · Mapped (2) |
| SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Hirschey M.D., Shimazu T., Goetzman E., Jing E., Schwer B., Lombard D.B., Grueter C.A., Harris C., Biddinger S., Ilkayeva O.R. et al. Nature 464:121-125(2010) · Mapped (8) |
| DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation. Koliwad S.K., Streeper R.S., Monetti M., Cornelissen I., Chan L., Terayama K., Naylor S., Rao M., Hubbard B., Farese R.V. Jr. J. Clin. Invest. 120:756-767(2010) · Mapped (7) |
| Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. Koliwad S.K., Kuo T., Shipp L.E., Gray N.E., Backhed F., So A.Y., Farese R.V. Jr., Wang J.C. J. Biol. Chem. 284:25593-25601(2009) · Mapped (23) |
| Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Yen C.L., Cheong M.L., Grueter C., Zhou P., Moriwaki J., Wong J.S., Hubbard B., Marmor S., Farese R.V. Jr. Nat. Med. 15:442-446(2009) · Mapped (1) |
| The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. Stone S.J., Levin M.C., Zhou P., Han J., Walther T.C., Farese R.V. Jr. J. Biol. Chem. 284:5352-5361(2009) · Mapped (6) |
| Retinol esterification by DGAT1 is essential for retinoid homeostasis in murine skin. Shih M.Y., Kane M.A., Zhou P., Yen C.L., Streeper R.S., Napoli J.L., Farese R.V. Jr. J. Biol. Chem. 284:4292-4299(2009) · UniProtKB (1) · Mapped (3) |
| Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis. Yen C.L., Stone S.J., Koliwad S., Harris C., Farese R.V. Jr. J. Lipid Res. 49:2283-2301(2008) · Mapped (8) |
| Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. Minehira K., Young S.G., Villanueva C.J., Yetukuri L., Oresic M., Hellerstein M.K., Farese R.V. Jr., Horton J.D., Preitner F., Thorens B. et al. J. Lipid Res. 49:2038-2044(2008) · Mapped (3) |
| Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle. Levin M.C., Monetti M., Watt M.J., Sajan M.P., Stevens R.D., Bain J.R., Newgard C.B., Farese R.V. Sr., Farese R.V. Jr. Am. J. Physiol. Endocrinol. Metab. 293:E1772-81(2007) · Mapped (1) |
| Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Lombard D.B., Alt F.W., Cheng H.L., Bunkenborg J., Streeper R.S., Mostoslavsky R., Kim J., Yancopoulos G., Valenzuela D., Murphy A. et al. Mol. Cell. Biol. 27:8807-8814(2007) · UniProtKB (1) · Mapped (10) |
| LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA). Chan L.C., Peters W., Xu Y., Chun J., Farese R.V. Jr., Cases S. J. Leukoc. Biol. 82:1193-1200(2007) · Mapped (4) |
| Membrane topology and identification of key functional amino acid residues of murine acyl-CoA:diacylglycerol acyltransferase-2. Stone S.J., Levin M.C., Farese R.V. Jr. J. Biol. Chem. 281:40273-40282(2006) · UniProtKB (1) |