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LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.

Matta S., Van Kolen K., da Cunha R., van den Bogaart G., Mandemakers W., Miskiewicz K., De Bock P.J., Morais V.A., Vilain S., Haddad D. et al.

Neuron 75:1008-1021(2012) · Mapped (7)

Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.

Vos M., Esposito G., Edirisinghe J.N., Vilain S., Haddad D.M., Slabbaert J.R., Van Meensel S., Schaap O., De Strooper B., Meganathan R. et al.

Science 336:1306-1310(2012) · UniProtKB (1) · Mapped (11)

Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate.

Motamedi-Shad N., Garfagnini T., Penco A., Relini A., Fogolari F., Corazza A., Esposito G., Bemporad F., Chiti F.

Nat. Struct. Mol. Biol. 19:547-54, 2012:S1-2(2012) · Mapped (4)

Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila.

Humphrey D.M., Parsons R.B., Ludlow Z.N., Riemensperger T., Esposito G., Verstreken P., Jacobs H.T., Birman S., Hirth F.

Hum. Mol. Genet. 21:2698-2712(2012) · Mapped (16)

OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors.

Lu J., Lian G., Zhou H., Esposito G., Steardo L., Delli-Bovi L.C., Hecht J.L., Lu Q.R., Sheen V.

Hum. Mol. Genet. 21:2330-2340(2012) · Mapped (3)

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Vilain S., Esposito G., Haddad D., Schaap O., Dobreva M.P., Vos M., Van Meensel S., Morais V.A., De Strooper B., Verstreken P.

PLoS Genet. 8:e1002456-e1002456(2012) · Mapped (18)

Cannabidiol reduces Abeta-induced neuroinflammation and promotes hippocampal neurogenesis through PPARgamma involvement.

Esposito G., Scuderi C., Valenza M., Togna G.I., Latina V., De Filippis D., Cipriano M., Carratu M.R., Iuvone T., Steardo L.

PLoS ONE 6:e28668-e28668(2011) · Mapped (1)

Somatic mutations in NKX2-5, GATA4, and HAND1 are not a common cause of tetralogy of Fallot or hypoplastic left heart.

Esposito G., Butler T.L., Blue G.M., Cole A.D., Sholler G.F., Kirk E.P., Grossfeld P., Perryman B.M., Harvey R.P., Winlaw D.S.

Am. J. Med. Genet. A 155A:2416-2421(2011) · Mapped (8)

Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with rab geranylgeranyl transferase.

Esposito G., De Falco F., Tinto N., Testa F., Vitagliano L., Tandurella I.C., Iannone L., Rossi S., Rinaldi E., Simonelli F. et al.

Hum. Mutat. 32:1460-1469(2011) · UniProtKB (1)

Pediatric adrenocortical tumors: morphological diagnostic criteria and immunohistochemical expression of matrix metalloproteinase type 2 and human leucocyte-associated antigen (HLA) class II antigens. Results from the Italian Pediatric Rare Tumor (TREP) Study project.

Magro G., Esposito G., Cecchetto G., Dall'Igna P., Marcato R., Gambini C., Boldrini R., Collini P., D'Onofrio V., Salfi N. et al.

Hum. Pathol. 43:31-39(2012) · Mapped (308)

S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors.

Lu J., Esposito G., Scuderi C., Steardo L., Delli-Bovi L.C., Hecht J.L., Dickinson B.C., Chang C.J., Mori T., Sheen V.

PLoS ONE 6:e22126-e22126(2011) · Mapped (12)

HMGB1 attenuates cardiac remodelling in the failing heart via enhanced cardiac regeneration and miR-206-mediated inhibition of TIMP-3.

Limana F., Esposito G., D'Arcangelo D., Di Carlo A., Romani S., Melillo G., Mangoni A., Bertolami C., Pompilio G., Germani A. et al.

PLoS ONE 6:e19845-e19845(2011) · Mapped (3)

The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.

Raimondi S., Barbarini N., Mangione P., Esposito G., Ricagno S., Bolognesi M., Zorzoli I., Marchese L., Soria C., Bellazzi R. et al.

BMC Evol. Biol. 11:159-159(2011) · Mapped (1)

Glycolytic phenotype and AMP kinase modify the pathologic response of tumor xenografts to VEGF neutralization.

Nardo G., Favaro E., Curtarello M., Moserle L., Zulato E., Persano L., Rossi E., Esposito G., Crescenzi M., Casanovas O. et al.

Cancer Res. 71:4214-4225(2011) · Mapped (3)

S100B protein in the gut: the evidence for enteroglial-sustained intestinal inflammation.

Cirillo C., Sarnelli G., Esposito G., Turco F., Steardo L., Cuomo R.

World J. Gastroenterol. 17:1261-1266(2011) · Mapped (1)

EGFR trans-activation by urotensin II receptor is mediated by beta-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy.

Esposito G., Perrino C., Cannavo A., Schiattarella G.G., Borgia F., Sannino A., Pironti G., Gargiulo G., Di Serafino L., Franzone A. et al.

Basic Res. Cardiol. 106:577-589(2011) · Mapped (15)

The complete DNA sequence and analysis of the virulence plasmid and of five additional plasmids carried by Shiga toxin-producing Escherichia coli O26:H11 strain H30.

Fratamico P.M., Yan X., Caprioli A., Esposito G., Needleman D.S., Pepe T., Tozzoli R., Cortesi M.L., Morabito S.

Int. J. Med. Microbiol. 301:192-203(2011) · UniProtKB (101)

The G protein regulators EGL-10 and EAT-16, the Gialpha GOA-1 and the G(q)alpha EGL-30 modulate the response of the C. elegans ASH polymodal nociceptive sensory neurons to repellents.

Esposito G., Amoroso M.R., Bergamasco C., Di Schiavi E., Bazzicalupo P.

BMC Biol. 8:138-138(2010) · Mapped (11)

Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils.

Giorgetti S., Raimondi S., Pagano K., Relini A., Bucciantini M., Corazza A., Fogolari F., Codutti L., Salmona M., Mangione P. et al.

J. Biol. Chem. 286:2121-2131(2011) · Mapped (7)

GATA4 mutations in 357 unrelated patients with congenital heart malformation.

Butler T.L., Esposito G., Blue G.M., Cole A.D., Costa M.W., Waddell L.B., Walizada G., Sholler G.F., Kirk E.P., Feneley M. et al.

Genet Test Mol Biomarkers 14:797-802(2010) · Mapped (6)

Hereditary fructose intolerance: functional study of two novel ALDOB natural variants and characterization of a partial gene deletion.

Esposito G., Imperato M.R., Ieno L., Sorvillo R., Benigno V., Parenti G., Parini R., Vitagliano L., Zagari A., Salvatore F.

Hum. Mutat. 31:1294-1303(2010) · Mapped (3)

Folding and fibrillogenesis: clues from beta2-microglobulin.

Rennella E., Corazza A., Giorgetti S., Fogolari F., Viglino P., Porcari R., Verga L., Stoppini M., Bellotti V., Esposito G.

J. Mol. Biol. 401:286-297(2010) · Mapped (7)

AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress.

Perrino C., Feliciello A., Schiattarella G.G., Esposito G., Guerriero R., Zaccaro L., Del Gatto A., Saviano M., Garbi C., Carangi R. et al.

Cardiovasc. Res. 88:101-110(2010) · Mapped (2)

Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR.

Corazza A., Rennella E., Schanda P., Mimmi M.C., Cutuil T., Raimondi S., Giorgetti S., Fogolari F., Viglino P., Frydman L. et al.

J. Biol. Chem. 285:5827-5835(2010) · Mapped (7)

Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload.

Esposito G., Perrino C., Schiattarella G.G., Belardo L., di Pietro E., Franzone A., Capretti G., Gargiulo G., Pironti G., Cannavo A. et al.

Hypertension 55:137-143(2010) · Mapped (27)

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