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1 - 25 of 164 results for author:"Elledge S.J." in Literature citations

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The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication.

John S.P., Chin C.R., Perreira J.M., Feeley E.M., Aker A.M., Savidis G., Smith S.E., Elia A.E., Everitt A.R., Vora M. et al.

J. Virol. 87:7837-7852(2013) · Mapped (1)

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

Liu Q., Xu C., Kirubakaran S., Zhang X., Hur W., Liu Y., Kwiatkowski N.P., Wang J., Westover K.D., Gao P. et al.

Cancer Res. 73:2574-2586(2013) · Mapped (6)

STOP gene Phactr4 is a tumor suppressor.

Solimini N.L., Liang A.C., Xu C., Pavlova N.N., Xu Q., Davoli T., Li M.Z., Wong K.K., Elledge S.J.

Proc. Natl. Acad. Sci. U.S.A. 110:E407-14(2013) · Mapped (1)

Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila.

Wang C.I., Alekseyenko A.A., LeRoy G., Elia A.E., Gorchakov A.A., Britton L.M., Elledge S.J., Kharchenko P.V., Garcia B.A., Kuroda M.I.

Nat. Struct. Mol. Biol. 20:202-209(2013) · Mapped (76)

Reactivation of latent HIV-1 by inhibition of BRD4.

Zhu J., Gaiha G.D., John S.P., Pertel T., Chin C.R., Gao G., Qu H., Walker B.D., Elledge S.J., Brass A.L.

Cell Rep 2:807-816(2012) · Mapped (7)

Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress.

Ciccia A., Nimonkar A.V., Hu Y., Hajdu I., Achar Y.J., Izhar L., Petit S.A., Adamson B., Yoon J.C., Kowalczykowski S.C. et al.

Mol. Cell 47:396-409(2012) · UniProtKB (2) · Mapped (8)

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.

Adamson B., Smogorzewska A., Sigoillot F.D., King R.W., Elledge S.J.

Nat. Cell Biol. 14:318-328(2012) · Mapped (22)

A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.

Kessler J.D., Kahle K.T., Sun T., Meerbrey K.L., Schlabach M.R., Schmitt E.M., Skinner S.O., Xu Q., Li M.Z., Hartman Z.C. et al.

Science 335:348-353(2012) · Mapped (17)

IFITM3 inhibits influenza A virus infection by preventing cytosolic entry.

Feeley E.M., Sims J.S., John S.P., Chin C.R., Pertel T., Chen L.M., Gaiha G.D., Ryan B.J., Donis R.O., Elledge S.J. et al.

PLoS Pathog. 7:E1002337-E1002337(2011) · UniProtKB (1)

Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.

Joo W., Xu G., Persky N.S., Smogorzewska A., Rudge D.G., Buzovetsky O., Elledge S.J., Pavletich N.P.

Science 333:312-316(2011) · Mapped (6)

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.

Cotta-Ramusino C., McDonald E.R. III, Hurov K., Sowa M.E., Harper J.W., Elledge S.J.

Science 332:1313-1317(2011) · UniProtKB (11) · Mapped (1)

Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate.

Emanuele M.J., Ciccia A., Elia A.E., Elledge S.J.

Proc. Natl. Acad. Sci. U.S.A. 108:9845-9850(2011) · UniProtKB (2) · Mapped (10)

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase.

Sun T., Aceto N., Meerbrey K.L., Kessler J.D., Zhou C., Migliaccio I., Nguyen D.X., Pavlova N.N., Botero M., Huang J. et al.

Cell 144:703-718(2011) · Mapped (6)

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus.

Huang I.C., Bailey C.C., Weyer J.L., Radoshitzky S.R., Becker M.M., Chiang J.J., Brass A.L., Ahmed A.A., Chi X., Dong L. et al.

PLoS Pathog. 7:E1001258-E1001258(2011) · UniProtKB (6)

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

O'Connell B.C., Adamson B., Lydeard J.R., Sowa M.E., Ciccia A., Bredemeyer A.L., Schlabach M., Gygi S.P., Elledge S.J., Harper J.W.

Mol. Cell 40:645-657(2010) · UniProtKB (2) · Mapped (1)

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

Hurov K.E., Cotta-Ramusino C., Elledge S.J.

Genes Dev. 24:1939-1950(2010) · UniProtKB (8) · Mapped (2)

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence.

Burrows A.E., Smogorzewska A., Elledge S.J.

Proc. Natl. Acad. Sci. U.S.A. 107:14280-14285(2010) · UniProtKB (2) · Mapped (47)

Wnt signaling regulates mitochondrial physiology and insulin sensitivity.

Yoon J.C., Ng A., Kim B.H., Bianco A., Xavier R.J., Elledge S.J.

Genes Dev. 24:1507-1518(2010) · Mapped (4)

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.

Smogorzewska A., Desetty R., Saito T.T., Schlabach M., Lach F.P., Sowa M.E., Clark A.B., Kunkel T.A., Harper J.W., Colaiacovo M.P. et al.

Mol. Cell 39:36-47(2010) · UniProtKB (7) · Mapped (1)

Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53.

Fishler T., Li Y.Y., Wang R.H., Kim H.S., Sengupta K., Vassilopoulos A., Lahusen T., Xu X., Lee M.H., Liu Q. et al.

Oncogene 29:4007-4017(2010) · Mapped (24)

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus.

Brass A.L., Huang I.C., Benita Y., John S.P., Krishnan M.N., Feeley E.M., Ryan B.J., Weyer J.L., van der Weyden L., Fikrig E. et al.

Cell 139:1243-1254(2009) · UniProtKB (3) · Mapped (11)

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.

Knipscheer P., Raschle M., Smogorzewska A., Enoiu M., Ho T.V., Scharer O.D., Elledge S.J., Walter J.C.

Science 326:1698-1701(2009) · UniProtKB (1)

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart.

Ciccia A., Bredemeyer A.L., Sowa M.E., Terret M.E., Jallepalli P.V., Harper J.W., Elledge S.J.

Genes Dev. 23:2415-2425(2009) · Mapped (1)

Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication.

Shen X., Do H., Li Y., Chung W.H., Tomasz M., de Winter J.P., Xia B., Elledge S.J., Wang W., Li L.

Mol. Cell 35:716-723(2009) · Mapped (22)

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Svendsen J.M., Smogorzewska A., Sowa M.E., O'Connell B.C., Gygi S.P., Elledge S.J., Harper J.W.

Cell 138:63-77(2009) · UniProtKB (9) · Mapped (2)

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