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Literature citations Results

Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8.

Edwards J.P., Thornton A.M., Shevach E.M.

J. Immunol. 193:2843-2849(2014) · Mapped (3)

Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs.

Matkovich S.J., Edwards J.R., Grossenheider T.C., de Guzman Strong C., Dorn G.W.

Proc. Natl. Acad. Sci. U.S.A. 111:12264-12269(2014) · Mapped (17)

Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis.

Hai Y., Edwards J.E., Van Zandt M.C., Hoffmann K.F., Christianson D.W.

Biochemistry 53:4671-4684(2014) · UniProtKB (1)

An alcohol-sensing site in the calcium- and voltage-gated, large conductance potassium (BK) channel.

Bukiya A.N., Kuntamallappanavar G., Edwards J., Singh A.K., Shivakumar B., Dopico A.M.

Proc. Natl. Acad. Sci. U.S.A. 111:9313-9318(2014) · Mapped (35)

A PTPN11 allele encoding a catalytically impaired SHP2 protein in a patient with a Noonan syndrome phenotype.

Edwards J.J., Martinelli S., Pannone L., Lo I.F., Shi L., Edelmann L., Tartaglia M., Luk H.M., Gelb B.D.

Am. J. Med. Genet. A 164:2351-2355(2014) · UniProtKB (1)

PPARdelta activation attenuates hepatic steatosis in Ldlr-/- mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity.

Bojic L.A., Telford D.E., Fullerton M.D., Ford R.J., Sutherland B.G., Edwards J.Y., Sawyez C.G., Gros R., Kemp B.E., Steinberg G.R. et al.

J. Lipid Res. 55:1254-1266(2014) · Mapped (11)

RAF1 mutations in childhood-onset dilated cardiomyopathy.

Dhandapany P.S., Razzaque M.A., Muthusami U., Kunnoth S., Edwards J.J., Mulero-Navarro S., Riess I., Pardo S., Sheng J., Rani D.S. et al.

Nat. Genet. 46:635-639(2014) · UniProtKB (1) · Mapped (3)

RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.

McDonald L., Ferrari N., Terry A., Bell M., Mohammed Z.M., Orange C., Jenkins A., Muller W.J., Gusterson B.A., Neil J.C. et al.

Dis Model Mech 7:525-534(2014) · Mapped (11)

Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.

Wojciak-Stothard B., Abdul-Salam V.B., Lao K.H., Tsang H., Irwin D.C., Lisk C., Loomis Z., Stenmark K.R., Edwards J.C., Yuspa S.H. et al.

Circulation 129:1770-1780(2014) · Mapped (5)

Applications of a sugar-based surveillance system to track arboviruses in wild mosquito populations.

van den Hurk A.F., Hall-Mendelin S., Townsend M., Kurucz N., Edwards J., Ehlers G., Rodwell C., Moore F.A., McMahon J.L., Northill J.A. et al.

Vector Borne Zoonotic Dis. 14:66-73(2014) · UniProtKB (3)

Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.

Rutherford C., Childs S., Ohotski J., McGlynn L., Riddick M., MacFarlane S., Tasker D., Pyne S., Pyne N.J., Edwards J. et al.

Cell Death Dis 4:e927-e927(2013) · Mapped (14)

SIRT2: tumour suppressor or tumour promoter in operable breast cancer?

McGlynn L.M., Zino S., MacDonald A.I., Curle J., Reilly J.E., Mohammed Z.M., McMillan D.C., Mallon E., Payne A.P., Edwards J. et al.

Eur. J. Cancer 50:290-301(2014) · Mapped (4)

Peroxisome proliferator-activated receptor delta agonist GW1516 attenuates diet-induced aortic inflammation, insulin resistance, and atherosclerosis in low-density lipoprotein receptor knockout mice.

Bojic L.A., Burke A.C., Chhoker S.S., Telford D.E., Sutherland B.G., Edwards J.Y., Sawyez C.G., Tirona R.G., Yin H., Pickering J.G. et al.

Arterioscler. Thromb. Vasc. Biol. 34:52-60(2014) · Mapped (10)

IGFBP-5 enhances epithelial cell adhesion and protects epithelial cells from TGFbeta1-induced mesenchymal invasion.

Vijayan A., Guha D., Ameer F., Kaziri I., Mooney C.C., Bennett L., Sureshbabu A., Tonner E., Beattie J., Allan G.J. et al.

Int. J. Biochem. Cell Biol. 45:2774-2785(2013) · Mapped (14)

Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.

Li S., Shen D., Shao J., Crowder R., Liu W., Prat A., He X., Liu S., Hoog J., Lu C. et al.

Cell Rep 4:1116-1130(2013) · Mapped (71)

Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients.

McCall P., Adams C.E., Willder J.M., Bennett L., Qayyum T., Orange C., Underwood M.A., Edwards J.

Int J Mol Sci 14:16656-16671(2013) · Mapped (14)

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells.

Yang W., Guo D., Harris M.A., Cui Y., Gluhak-Heinrich J., Wu J., Chen X.D., Skinner C., Nyman J.S., Edwards J.R. et al.

J. Cell. Sci. 126:4085-4098(2013) · Mapped (4)

Regulation of the expression of GARP/latent TGF-beta1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.

Edwards J.P., Fujii H., Zhou A.X., Creemers J., Unutmaz D., Shevach E.M.

J. Immunol. 190:5506-5515(2013) · Mapped (13)

Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata.

Fu Y., Phan Q.T., Luo G., Solis N.V., Liu Y., Cormack B.P., Edwards J.E. Jr., Ibrahim A.S., Filler S.G.

Infect. Immun. 81:2528-2535(2013) · UniProtKB (1)

Activation of NF-kappa B signaling promotes growth of prostate cancer cells in bone.

Jin R., Sterling J.A., Edwards J.R., DeGraff D.J., Lee C., Park S.I., Matusik R.J.

PLoS ONE 8:e60983-e60983(2013) · Mapped (2)

Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression.

Patel R., Gao M., Ahmad I., Fleming J., Singh L.B., Rai T.S., McKie A.B., Seywright M., Barnetson R.J., Edwards J. et al.

J. Clin. Invest. 123:1157-1175(2013) · Mapped (29)

Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.

Edwards J.S., Betts L., Frazier M.L., Pollet R.M., Kwong S.M., Walton W.G., Ballentine W.K., Huang J.J., Habibi S., Del Campo M. et al.

Proc. Natl. Acad. Sci. U.S.A. 110:2804-2809(2013) · UniProtKB (2)

Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients.

Willder J.M., Heng S.J., McCall P., Adams C.E., Tannahill C., Fyffe G., Seywright M., Horgan P.G., Leung H.Y., Underwood M.A. et al.

Br. J. Cancer 108:139-148(2013) · Mapped (1)

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

Dovey O.M., Foster C.T., Conte N., Edwards S.A., Edwards J.M., Singh R., Vassiliou G., Bradley A., Cowley S.M.

Blood 121:1335-1344(2013) · Mapped (7)

Interactions between MAP kinase and oestrogen receptor in human breast cancer.

McGlynn L.M., Tovey S., Bartlett J.M., Doughty J., Cooke T.G., Edwards J.

Eur. J. Cancer 49:1176-1186(2013) · Mapped (10)

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