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Literature citations Results

Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus.

Chan L.C., Chaili S., Filler S.G., Barr K., Wang H., Kupferwasser D., Edwards J.E. Jr., Xiong Y.Q., Ibrahim A.S., Miller L.S. et al.

Infect. Immun. 83:4427-4437(2015) · Mapped (4)

The regulatory factor ZFHX3 modifies circadian function in SCN via an AT motif-driven axis.

Parsons M.J., Brancaccio M., Sethi S., Maywood E.S., Satija R., Edwards J.K., Jagannath A., Couch Y., Finelli M.J., Smyllie N.J. et al.

Cell 162:607-621(2015) · UniProtKB (1) · Mapped (39)

An internal thioester in a pathogen surface protein mediates covalent host binding.

Walden M., Edwards J.M., Dziewulska A.M., Bergmann R., Saalbach G., Kan S.Y., Miller O.K., Weckener M., Jackson R.J., Shirran S.L. et al.

Elife 4:0-0(2015) · UniProtKB (2) · Mapped (1)

The clinical management of hyperglycemia in pregnancy complicated by maturity-onset diabetes of the young.

Bacon S., Schmid J., McCarthy A., Edwards J., Fleming A., Kinsley B., Firth R., Byrne B., Gavin C., Byrne M.M.

Am. J. Obstet. Gynecol. 213:236.e1-7(2015) · Mapped (32)

GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury.

Zonouzi M., Scafidi J., Li P., McEllin B., Edwards J., Dupree J.L., Harvey L., Sun D., Hubner C.A., Cull-Candy S.G. et al.

Nat. Neurosci. 18:674-682(2015) · Mapped (3)

Coinfection with multiple strains of bovine papular stomatitis virus.

Huang T., Tulman E.R., Diel D.G., Khatiwada S., Sims W., Edwards J.F., Wen X., Kutish G.F., Rock D.L., Delhon G.

Arch. Virol. 160:1527-1532(2015) · UniProtKB (229)

Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer.

Staquicini F.I., Qian M.D., Salameh A., Dobroff A.S., Edwards J.K., Cimino D.F., Moeller B.J., Kelly P., Nunez M.I., Tang X. et al.

J. Biol. Chem. 290:7345-7359(2015) · Mapped (6)

Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance.

Yu F., Sharma S., Edwards J., Feigenbaum L., Zhu J.

Nat. Immunol. 16:197-206(2015) · Mapped (30)

Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.

Yang Y.M., Yuan H., Edwards J.G., Skayian Y., Ochani K., Miller E.J., Sehgal P.B.

Mol. Med. 20:625-638(2014) · Mapped (17)

Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation.

Mardilovich K., Gabrielsen M., McGarry L., Orange C., Patel R., Shanks E., Edwards J., Olson M.F.

Mol. Cancer Ther. 14:246-258(2015) · Mapped (12)

Hypertension: new roles for CUL-3 in the kidney.

Edwards J.K.

Nat Rev Nephrol 10:675-675(2014) · Mapped (3)

Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8.

Edwards J.P., Thornton A.M., Shevach E.M.

J. Immunol. 193:2843-2849(2014) · Mapped (4)

Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs.

Matkovich S.J., Edwards J.R., Grossenheider T.C., de Guzman Strong C., Dorn G.W.

Proc. Natl. Acad. Sci. U.S.A. 111:12264-12269(2014) · Mapped (17)

CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer.

Macpherson I.R., Rainero E., Mitchell L.E., van den Berghe P.V., Speirs C., Dozynkiewicz M.A., Chaudhary S., Kalna G., Edwards J., Timpson P. et al.

J. Cell. Sci. 127:3893-3901(2014) · Mapped (7)

Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis.

Hai Y., Edwards J.E., Van Zandt M.C., Hoffmann K.F., Christianson D.W.

Biochemistry 53:4671-4684(2014) · UniProtKB (1)

Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer.

Ferrari N., Mohammed Z.M., Nixon C., Mason S.M., Mallon E., McMillan D.C., Morris J.S., Cameron E.R., Edwards J., Blyth K.

PLoS ONE 9:e100759-e100759(2014) · Mapped (5)

An alcohol-sensing site in the calcium- and voltage-gated, large conductance potassium (BK) channel.

Bukiya A.N., Kuntamallappanavar G., Edwards J., Singh A.K., Shivakumar B., Dopico A.M.

Proc. Natl. Acad. Sci. U.S.A. 111:9313-9318(2014) · Mapped (35)

A PTPN11 allele encoding a catalytically impaired SHP2 protein in a patient with a Noonan syndrome phenotype.

Edwards J.J., Martinelli S., Pannone L., Lo I.F., Shi L., Edelmann L., Tartaglia M., Luk H.M., Gelb B.D.

Am. J. Med. Genet. A 164:2351-2355(2014) · UniProtKB (1)

PPARdelta activation attenuates hepatic steatosis in Ldlr-/- mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity.

Bojic L.A., Telford D.E., Fullerton M.D., Ford R.J., Sutherland B.G., Edwards J.Y., Sawyez C.G., Gros R., Kemp B.E., Steinberg G.R. et al.

J. Lipid Res. 55:1254-1266(2014) · Mapped (11)

RAF1 mutations in childhood-onset dilated cardiomyopathy.

Dhandapany P.S., Razzaque M.A., Muthusami U., Kunnoth S., Edwards J.J., Mulero-Navarro S., Riess I., Pardo S., Sheng J., Rani D.S. et al.

Nat. Genet. 46:635-639(2014) · UniProtKB (1) · Mapped (5)

RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.

McDonald L., Ferrari N., Terry A., Bell M., Mohammed Z.M., Orange C., Jenkins A., Muller W.J., Gusterson B.A., Neil J.C. et al.

Dis Model Mech 7:525-534(2014) · Mapped (11)

Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.

Wojciak-Stothard B., Abdul-Salam V.B., Lao K.H., Tsang H., Irwin D.C., Lisk C., Loomis Z., Stenmark K.R., Edwards J.C., Yuspa S.H. et al.

Circulation 129:1770-1780(2014) · Mapped (5)

Applications of a sugar-based surveillance system to track arboviruses in wild mosquito populations.

van den Hurk A.F., Hall-Mendelin S., Townsend M., Kurucz N., Edwards J., Ehlers G., Rodwell C., Moore F.A., McMahon J.L., Northill J.A. et al.

Vector Borne Zoonotic Dis. 14:66-73(2014) · UniProtKB (3)

Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.

Rutherford C., Childs S., Ohotski J., McGlynn L., Riddick M., MacFarlane S., Tasker D., Pyne S., Pyne N.J., Edwards J. et al.

Cell Death Dis 4:e927-e927(2013) · Mapped (15)

SIRT2: tumour suppressor or tumour promoter in operable breast cancer?

McGlynn L.M., Zino S., MacDonald A.I., Curle J., Reilly J.E., Mohammed Z.M., McMillan D.C., Mallon E., Payne A.P., Edwards J. et al.

Eur. J. Cancer 50:290-301(2014) · Mapped (4)

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