1 - 25 of 33 results for author:"Duyster J." in Literature citations
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| Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M. Illert A.L., Zech M., Moll C., Albers C., Kreutmair S., Peschel C., Bassermann F., Duyster J. J. Biol. Chem. 287:37997-38005(2012) · Mapped (12) |
| Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase. Illert A.L., Kawaguchi H., Antinozzi C., Bassermann F., Quintanilla-Martinez L., von Klitzing C., Hiwatari M., Peschel C., de Rooij D.G., Morris S.W. et al. Development 139:2523-2534(2012) · Mapped (6) |
| Cks1 is required for tumor cell proliferation but not sufficient to induce hematopoietic malignancies. Kratzat S., Nikolova V., Miething C., Hoellein A., Schoeffmann S., Gorka O., Pietschmann E., Illert A.L., Ruland J., Peschel C. et al. PLoS ONE 7:e37433-e37433(2012) · Mapped (8) |
| APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1. Klitzing C.v., Huss R., Illert A.L., Froschl A., Wotzel S., Peschel C., Bassermann F., Duyster J. PLoS ONE 6:e28998-e28998(2011) · Mapped (9) |
| The epidermal growth factor receptor-L861Q mutation increases kinase activity without leading to enhanced sensitivity toward epidermal growth factor receptor kinase inhibitors. Kancha R.K., Peschel C., Duyster J. J Thorac Oncol 6:387-392(2011) · Mapped (19) |
| The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro. von Bubnoff N., Gorantla S.P., Engh R.A., Oliveira T.M., Thone S., Aberg E., Peschel C., Duyster J. Oncogene 30:933-943(2011) · UniProtKB (1) |
| Oncogenic JAK2V617F requires an intact SH2-like domain for constitutive activation and induction of a myeloproliferative disease in mice. Gorantla S.P., Dechow T.N., Grundler R., Illert A.L., Zum Buschenfelde C.M., Kremer M., Peschel C., Duyster J. Blood 116:4600-4611(2010) · Mapped (3) |
| ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer. Baumgart A., Seidl S., Vlachou P., Michel L., Mitova N., Schatz N., Specht K., Koch I., Schuster T., Grundler R. et al. Cancer Res. 70:5368-5378(2010) · Mapped (11) |
| C/EBPbeta expression in ALK-positive anaplastic large cell lymphomas is required for cell proliferation and is induced by the STAT3 signaling pathway. Anastasov N., Bonzheim I., Rudelius M., Klier M., Dau T., Angermeier D., Duyster J., Pittaluga S., Fend F., Raffeld M. et al. Haematologica 95:760-767(2010) · Mapped (10) |
| Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway. Markova B., Albers C., Breitenbuecher F., Melo J.V., Brummendorf T.H., Heidel F., Lipka D., Duyster J., Huber C., Fischer T. Oncogene 29:739-751(2010) · Mapped (18) |
| E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease. Bandi S.R., Brandts C., Rensinghoff M., Grundler R., Tickenbrock L., Kohler G., Duyster J., Berdel W.E., Muller-Tidow C., Serve H. et al. Blood 114:4197-4208(2009) · Mapped (3) |
| Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. Grundler R., Brault L., Gasser C., Bullock A.N., Dechow T., Woetzel S., Pogacic V., Villa A., Ehret S., Berridge G. et al. J. Exp. Med. 206:1957-1970(2009) · UniProtKB (1) · Mapped (7) |
| CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes. Reindl C., Quentmeier H., Petropoulos K., Greif P.A., Benthaus T., Argiropoulos B., Mellert G., Vempati S., Duyster J., Buske C. et al. Clin. Cancer Res. 15:2238-2247(2009) · Mapped (1) |
| Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor. Breitenbuecher F., Schnittger S., Grundler R., Markova B., Carius B., Brecht A., Duyster J., Haferlach T., Huber C., Fischer T. Blood 113:4074-4077(2009) · Mapped (2) |
| Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells. Fanta S., Sonnenberg M., Skorta I., Duyster J., Miething C., Aulitzky W.E., van der Kuip H. Oncogene 27:4380-4384(2008) · Mapped (19) |
| Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations. Bremm A., Walch A., Fuchs M., Mages J., Duyster J., Keller G., Hermannstadter C., Becker K.F., Rauser S., Langer R. et al. Cancer Res. 68:707-714(2008) · Mapped (25) |
| NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Greten F.R., Arkan M.C., Bollrath J., Hsu L.C., Goode J., Miething C., Goktuna S.I., Neuenhahn M., Fierer J., Paxian S. et al. Cell 130:918-931(2007) · Mapped (16) |
| The immunogenicity of Bcr-Abl expressing dendritic cells is dependent on the Bcr-Abl kinase activity and dominated by Bcr-Abl regulated antigens. Scheich F., Duyster J., Peschel C., Bernhard H. Blood 110:2556-2560(2007) · Mapped (41) |
| Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment. Miething C., Grundler R., Mugler C., Brero S., Hoepfl J., Geigl J., Speicher M.R., Ottmann O., Peschel C., Duyster J. Proc. Natl. Acad. Sci. U.S.A. 104:4594-4599(2007) · Mapped (5) |
| NPM-ALK-dependent expression of the transcription factor CCAAT/enhancer binding protein beta in ALK-positive anaplastic large cell lymphoma. Quintanilla-Martinez L., Pittaluga S., Miething C., Klier M., Rudelius M., Davies-Hill T., Anastasov N., Martinez A., Vivero A., Duyster J. et al. Blood 108:2029-2036(2006) · Mapped (25) |
| NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry. Bassermann F., von Klitzing C., Munch S., Bai R.-Y., Kawaguchi H., Morris S.W., Peschel C., Duyster J. |
| Phosphorylation of grb10 regulates its interaction with 14-3-3. Urschel S., Bassermann F., Bai R.Y., Munch S., Peschel C., Duyster J. J. Biol. Chem. 280:16987-16993(2005) · UniProtKB (5) · Mapped (28) |
| FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model. Grundler R., Miething C., Thiede C., Peschel C., Duyster J. Blood 105:4792-4799(2005) · Mapped (5) |
| Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Burchert A., Cai D., Hofbauer L.C., Samuelsson M.K., Slater E.P., Duyster J., Ritter M., Hochhaus A., Muller R., Eilers M. et al. Blood 103:3480-3489(2004) · Mapped (31) |
| Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity. Cussac D., Greenland C., Roche S., Bai R.Y., Duyster J., Morris S.W., Delsol G., Allouche M., Payrastre B. Blood 103:1464-1471(2004) · Mapped (22) |