| Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer. Qian X., Durkin M.E., Wang D., Tripathi B.K., Olson L., Yang X.Y., Vass W.C., Popescu N.C., Lowy D.R.
Cancer Res. 72:5900-5911(2012) · Mapped (17) |
| Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma. Lee Y.H., Andersen J.B., Song H.T., Judge A.D., Seo D., Ishikawa T., Marquardt J.U., Kitade M., Durkin M.E., Raggi C. et al.
Cancer Res. 70:8264-8269(2010) · Mapped (3) |
| Deleted in liver cancer 3 (DLC-3), a novel Rho GTPase-activating protein, is downregulated in cancer and inhibits tumor cell growth. Durkin M.E., Ullmannova V., Guan M., Popescu N.C.
Oncogene 26:4580-4589(2007) · UniProtKB (1) |
| GTF2IRD1 in craniofacial development of humans and mice. Tassabehji M., Hammond P., Karmiloff-Smith A., Thompson P., Thorgeirsson S.S., Durkin M.E., Popescu N.C., Hutton T., Metcalfe K., Rucka A. et al.
Science 310:1184-1187(2005) · Mapped (11) |
| DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development. Durkin M.E., Avner M.R., Huh C.G., Yuan B.Z., Thorgeirsson S.S., Popescu N.C.
FEBS Lett. 579:1191-1196(2005) · Mapped (12) |
| Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma. Park S.-W., Ludes-Meyers J., Zimonjic D.B., Durkin M.E., Popescu N.C., Aldaz C.M.
Br. J. Cancer 91:753-759(2004) · UniProtKB (1) |
| SMAD5 gene expression, rearrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinoma. Zimonjic D.B., Durkin M.E., Keck-Waggoner C.L., Park S.W., Thorgeirsson S.S., Popescu N.C.
Neoplasia 5:390-396(2003) · Mapped (3) |
| DNA variants of DLC-1, a candidate tumor suppressor gene in human hepatocellular carcinoma. Park S.W., Durkin M.E., Thorgeirsson S.S., Popescu N.C.
Int. J. Oncol. 23:133-137(2003) · Mapped (5) |
| Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers. Yuan B.Z., Durkin M.E., Popescu N.C.
Cancer Genet. Cytogenet. 140:113-117(2003) · Mapped (5) |
| DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity. Yuan B.Z., Zhou X., Durkin M.E., Zimonjic D.B., Gumundsdottir K., Eyfjord J.E., Thorgeirsson S.S., Popescu N.C.
Oncogene 22:445-450(2003) · Mapped (5) |
| Gene structure, tissue expression, and linkage mapping of the mouse DLC-1 gene (Arhgap7). Durkin M.E., Yuan B.-Z., Thorgeirsson S.S., Popescu N.C.
Gene 288:119-127(2002) · UniProtKB (1) · Mapped (20) |
| Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity. Iba K., Durkin M.E., Johnsen L., Hunziker E., Damgaard-Pedersen K., Zhang H., Engvall E., Albrechtsen R., Wewer U.M.
Mol. Cell. Biol. 21:7817-7825(2001) · Mapped (2) |
| Integration of a c-myc transgene results in disruption of the mouse Gtf2ird1 gene, the homologue of the human GTF2IRD1 gene hemizygously deleted in Williams-Beuren syndrome. Durkin M.E., Keck-Waggoner C.L., Popescu N.C., Thorgeirsson S.S.
Genomics 73:20-27(2001) · UniProtKB (2) · Mapped (31) |
| Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation. Durkin M.E., Albrechtsen R., Chambers D.M., Abbott C.M., Wewer U.M.
Biochem. Biophys. Res. Commun. 250:125-130(1998) · UniProtKB (1) · Mapped (6) |
| Tetranectin is a novel marker for myogenesis during embryonic development, muscle regeneration, and muscle cell differentiation in vitro. Wewer U.M., Iba K., Durkin M.E., Nielsen F.C., Loechel F., Gilpin B.J., Kuang W., Engvall E., Albrechtsen R.
Dev. Biol. 200:247-259(1998) · Mapped (2) |
| Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation. Durkin M.E., Loechel F., Mattei M.-G., Gilpin B.J., Albrechtsen R., Wewer U.M.
FEBS Lett. 411:296-300(1997) · UniProtKB (1) · Mapped (17) |
| Assignment of the gene for human tetranectin (TNA) to chromosome 3p22-->p21.3 by somatic cell hybrid mapping. Durkin M.E., Naylor S.L., Albrechtsen R., Wewer U.M.
Cytogenet. Cell Genet. 76:39-40(1997) · Mapped (2) |
| Structural organization of the human and mouse laminin beta2 chain genes, and alternative splicing at the 5' end of the human transcript. Durkin M.E., Gautam M., Loechel S., Sanes J.R., Merlie J.P., Albrechtsen R., Wewer U.M.
J. Biol. Chem. 271:13407-13416(1996) · UniProtKB (1) · Mapped (1) |
| Characterization of the 5' end of the mouse Ent gene encoding the basement membrane protein, entactin. Durkin M.E., Liu S.H., Reing J., Chung A.E.
Gene 132:261-266(1993) · UniProtKB (1) |
| A potential role for tetranectin in mineralization during osteogenesis. Wewer U.M., Ibaraki K., Schjorring P., Durkin M.E., Young M.F., Albrechtsen R.
J. Cell Biol. 127:1767-1775(1994) · Mapped (2) |
| Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas. Wewer U.M., Gerecke D.R., Durkin M.E., Kurtz K.S., Mattei M.-G., Champliaud M.-F., Burgeson R.E., Albrechtsen R.
Genomics 24:243-252(1994) · UniProtKB (1) · Mapped (2) |
| Exon organization of the mouse entactin gene corresponds to the structural domains of the polypeptide and has regional homology to the low-density lipoprotein receptor gene. Durkin M.E., Wewer U.M., Chung A.E.
Genomics 26:219-228(1995) · UniProtKB (1) |
| Carboxyl-terminal sequence of entactin deduced from a cDNA clone. Durkin M.E., Carlin B.E., Vergnes J., Bartos B.B., Merlie J., Chung A.E.
Proc. Natl. Acad. Sci. U.S.A. 84:1570-1574(1987) · UniProtKB (1) · Mapped (1) |
| Amino acid sequence and domain structure of entactin. Homology with epidermal growth factor precursor and low density lipoprotein receptor. Durkin M.E., Chakravarti S., Bartos B.B., Liu S.H., Friedman R.L., Chung A.E.
J. Cell Biol. 107:2749-2756(1988) · UniProtKB (2) |
| Primary structure of the mouse laminin B2 chain and comparison with laminin B1. Durkin M.E., Bartos B.B., Liu S.-H., Phillips S.L., Chung A.E.
Biochemistry 27:5198-5204(1988) · UniProtKB (1) · Mapped (8) |
