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Ars2 promotes proper replication-dependent histone mRNA 3' end formation.

Gruber J.J., Olejniczak S.H., Yong J., La Rocca G., Dreyfuss G., Thompson C.B.

Mol. Cell 45:87-98(2012) · Mapped (3)

Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly.

Zhang R., So B.R., Li P., Yong J., Glisovic T., Wan L., Dreyfuss G.

Cell 146:384-395(2011) · Mapped (9)

Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis.

Yong J., Kasim M., Bachorik J.L., Wan L., Dreyfuss G.

Mol. Cell 38:551-562(2010) · Mapped (3)

tRNA binds to cytochrome c and inhibits caspase activation.

Mei Y., Yong J., Liu H., Shi Y., Meinkoth J., Dreyfuss G., Yang X.

Mol. Cell 37:668-678(2010) · Mapped (7)

Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

Gruber J.J., Zatechka D.S., Sabin L.R., Yong J., Lum J.J., Kong M., Zong W.-X., Zhang Z., Lau C.-K., Rawlings J. et al.

Cell 138:328-339(2009) · UniProtKB (7) · Mapped (21)

Gemin5-snRNA interaction reveals an RNA binding function for WD repeat domains.

Lau C.K., Bachorik J.L., Dreyfuss G.

Nat. Struct. Mol. Biol. 16:486-491(2009) · Mapped (3)

SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing.

Zhang Z., Lotti F., Dittmar K., Younis I., Wan L., Kasim M., Dreyfuss G.

Cell 133:585-600(2008) · Mapped (12)

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

Diem M.D., Chan C.C., Younis I., Dreyfuss G.

Nat. Struct. Mol. Biol. 14:1173-1179(2007) · UniProtKB (3) · Mapped (1)

SMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediate.

Battle D.J., Kasim M., Wang J., Dreyfuss G.

J. Biol. Chem. 282:27953-27959(2007) · Mapped (3)

Positive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5.

Kim E.K., Noh K.T., Yoon J.H., Cho J.H., Yoon K.W., Dreyfuss G., Choi E.J.

Cell Death Differ. 14:1518-1528(2007) · Mapped (11)

The Gemin5 protein of the SMN complex identifies snRNAs.

Battle D.J., Lau C.-K., Wan L., Deng H., Lotti F., Dreyfuss G.

Mol. Cell 23:273-279(2006) · UniProtKB (1) · Mapped (2)

SMN mRNA and protein levels in peripheral blood: biomarkers for SMA clinical trials.

Sumner C.J., Kolb S.J., Harmison G.G., Jeffries N.O., Schadt K., Finkel R.S., Dreyfuss G., Fischbeck K.H.

Neurology 66:1067-1073(2006) · Mapped (13)

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

Kashima I., Yamashita A., Izumi N., Kataoka N., Morishita R., Hoshino S., Ohno M., Dreyfuss G., Ohno S.

Genes Dev. 20:355-367(2006) · UniProtKB (3) · Mapped (10)

The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy.

Wan L., Battle D.J., Yong J., Gubitz A.K., Kolb S.J., Wang J., Dreyfuss G.

Mol. Cell. Biol. 25:5543-5551(2005) · Mapped (3)

The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure.

Ma Y., Dostie J., Dreyfuss G., Van Duyne G.D.

Structure 13:883-892(2005) · UniProtKB (2)

eIF4A3 is a novel component of the exon junction complex.

Chan C.C., Dostie J., Diem M.D., Feng W., Mann M., Rappsilber J., Dreyfuss G.

RNA 10:200-209(2004) · UniProtKB (3)

Ce-Y14 and MAG-1, components of the exon-exon junction complex, are required for embryogenesis and germline sexual switching in Caenorhabditis elegans.

Kawano T., Kataoka N., Dreyfuss G., Sakamoto H.

Mech. Dev. 121:27-35(2004) · Mapped (4)

A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex.

Kataoka N., Dreyfuss G.

J. Biol. Chem. 279:7009-7013(2004) · UniProtKB (2)

Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode.

Rappsilber J., Friesen W.J., Paushkin S., Dreyfuss G., Mann M.

Anal. Chem. 75:3107-3114(2003) · UniProtKB (1)

Structure of the Y14-Magoh core of the exon junction complex.

Lau C.K., Diem M.D., Dreyfuss G., Van Duyne G.D.

Curr. Biol. 13:933-941(2003) · UniProtKB (2)

Essential role for the SMN complex in the specificity of snRNP assembly.

Pellizzoni L., Yong J., Dreyfuss G.

Science 298:1775-1779(2002) · Mapped (13)

The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway.

Massenet S., Pellizzoni L., Paushkin S., Mattaj I.W., Dreyfuss G.

Mol. Cell. Biol. 22:6533-6541(2002) · Mapped (10)

Translation is required to remove Y14 from mRNAs in the cytoplasm.

Dostie J., Dreyfuss G.

Curr. Biol. 12:1060-1067(2002) · UniProtKB (1)

The SMN complex, an assemblyosome of ribonucleoproteins.

Paushkin S., Gubitz A.K., Massenet S., Dreyfuss G.

Curr. Opin. Cell Biol. 14:305-312(2002) · UniProtKB (1)

Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex.

Baccon J., Pellizzoni L., Rappsilber J., Mann M., Dreyfuss G.

J. Biol. Chem. 277:31957-31962(2002) · UniProtKB (3)

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