24
results
for author:"Downes M."
in Literature Citations
| Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Downes M., Francois M., Ferguson C., Parton R.G., Koopman P. Hum. Mol. Genet. 18:2839-2850(2009) · Mapped (39) |
| SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Nofsinger R.R., Li P., Hong S.H., Jonker J.W., Barish G.D., Ying H., Cheng S.Y., Leblanc M., Xu W., Pei L. et al. Proc. Natl. Acad. Sci. U.S.A. 105:20021-20026(2008) · Mapped (9) |
| Sox18 induces development of the lymphatic vasculature in mice. Francois M., Caprini A., Hosking B., Orsenigo F., Wilhelm D., Browne C., Paavonen K., Karnezis T., Shayan R., Downes M. et al. Nature 456:643-647(2008) · Mapped (38) |
| AMPK and PPARdelta agonists are exercise mimetics. Narkar V.A., Downes M., Yu R.T., Embler E., Wang Y.X., Banayo E., Mihaylova M.M., Nelson M.C., Zou Y., Juguilon H. et al. Cell 134:405-415(2008) · Mapped (3) |
| Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Yamanaka K., Boillee S., Roberts E.A., Garcia M.L., McAlonis-Downes M., Mikse O.R., Cleveland D.W., Goldstein L.S. Proc. Natl. Acad. Sci. U.S.A. 105:7594-7599(2008) · Mapped (5) |
| PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Barish G.D., Atkins A.R., Downes M., Olson P., Chong L.W., Nelson M., Zou Y., Hwang H., Kang H., Curtiss L. et al. Proc. Natl. Acad. Sci. U.S.A. 105:4271-4276(2008) · Mapped (7) |
| PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Takata Y., Liu J., Yin F., Collins A.R., Lyon C.J., Lee C.H., Atkins A.R., Downes M., Barish G.D., Evans R.M. et al. Proc. Natl. Acad. Sci. U.S.A. 105:4277-4282(2008) · Mapped (11) |
| ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Alaynick W.A., Kondo R.P., Xie W., He W., Dufour C.R., Downes M., Jonker J.W., Giles W., Naviaux R.K., Giguere V. et al. Cell Metab. 6:13-24(2007) · Mapped (14) |
| Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Dufour C.R., Wilson B.J., Huss J.M., Kelly D.P., Alaynick W.A., Downes M., Evans R.M., Blanchette M., Giguere V. Cell Metab. 5:345-356(2007) · Mapped (2) |
| Benefit of farnesoid X receptor inhibition in obstructive cholestasis. Stedman C., Liddle C., Coulter S., Sonoda J., Alvarez J.G., Evans R.M., Downes M. Proc. Natl. Acad. Sci. U.S.A. 103:11323-11328(2006) · Mapped (9) |
| Progressive spinal axonal degeneration and slowness in ALS2-deficient mice. Yamanaka K., Miller T.M., McAlonis-Downes M., Chun S.J., Cleveland D.W. Ann. Neurol. 60:95-104(2006) · Mapped (3) |
| Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Inagaki T., Moschetta A., Lee Y.K., Peng L., Zhao G., Downes M., Yu R.T., Shelton J.M., Richardson J.A., Repa J.J. et al. Proc. Natl. Acad. Sci. U.S.A. 103:3920-3925(2006) · Mapped (4) |
| Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Stedman C.A., Liddle C., Coulter S.A., Sonoda J., Alvarez J.G., Moore D.D., Evans R.M., Downes M. Proc. Natl. Acad. Sci. U.S.A. 102:2063-2068(2005) · Mapped (8) |
| Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. Sonoda J., Chong L.W., Downes M., Barish G.D., Coulter S., Liddle C., Lee C.H., Evans R.M. Proc. Natl. Acad. Sci. U.S.A. 102:2198-2203(2005) · Mapped (3) |
| The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18. Hosking B.M., Wang S.C., Downes M., Koopman P., Muscat G.E. J. Biol. Chem. 279:5314-5322(2004) · Mapped (7) |
| A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Downes M., Verdecia M.A., Roecker A.J., Hughes R., Hogenesch J.B., Kast-Woelbern H.R., Bowman M.E., Ferrer J.L., Anisfeld A.M., Edwards P.A. et al. Mol. Cell 11:1079-1092(2003) · Mapped (3) |
| SOX18 and the transcriptional regulation of blood vessel development. Downes M., Koopman P. Trends Cardiovasc. Med. 11:318-324(2001) · Mapped (2) |
| Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Shi Y., Downes M., Xie W., Kao H.-Y., Ordentlich P., Tsai C.-C., Hon M., Evans R.M. Genes Dev. 15:1140-1151(2001) · UniProtKB (6) |
| A dynamic role for HDAC7 in MEF2-mediated muscle differentiation. Dressel U., Bailey P.J., Wang S.-C.M., Downes M., Evans R.M., Muscat G.E.O. J. Biol. Chem. 276:17007-17013(2001) · UniProtKB (2) |
| Identification of a nuclear domain with deacetylase activity. Downes M., Ordentlich P., Kao H.-Y., Alvarez J.G.A., Evans R.M. Proc. Natl. Acad. Sci. U.S.A. 97:10330-10335(2000) · UniProtKB (9) |
| Humanized xenobiotic response in mice expressing nuclear receptor SXR. Xie W., Barwick J.L., Downes M., Blumberg B., Simon C.M., Nelson M.C., Neuschwander-Tetri B.A., Brunt E.M., Guzelian P.S., Evans R.M. Nature 406:435-439(2000) · Mapped (6) |
| The genome sequence of Drosophila melanogaster. Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F. et al. Science 287:2185-2195(2000) · UniProtKB (17,223) · Mapped (13) |
| Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Kao H.-Y., Downes M., Ordentlich P., Evans R.M. |
| Unique forms of human and mouse nuclear receptor corepressor SMRT. Ordentlich P., Downes M., Xie W., Genin A., Spinner N.B., Evans R.M. Proc. Natl. Acad. Sci. U.S.A. 96:2639-2644(1999) · UniProtKB (2) · Mapped (4) |
