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1 - 25 of 35 results for author:"Donowitz M." in Literature citations

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Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.

Zizak M., Chen T., Bartonicek D., Sarker R., Zachos N.C., Cha B., Kovbasnjuk O., Korac J., Mohan S., Cole R. et al.

J. Biol. Chem. 287:13442-13456(2012) · Mapped (4)

Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3).

Lin Z., Jin S., Duan X., Wang T., Martini S., Hulamm P., Cha B., Hubbard A., Donowitz M., Guggino S.E.

J. Biol. Chem. 286:22833-22845(2011) · Mapped (6)

NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum.

Murtazina R., Kovbasnjuk O., Chen T.E., Zachos N.C., Chen Y., Kocinsky H.S., Hogema B.M., Seidler U., de Jonge H.R., Donowitz M.

Am. J. Physiol., Cell Physiol. 301:C126-36(2011) · Mapped (2)

Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles.

Donowitz M., Singh S., Singh P., Chakraborty M., Chen Y., Murtazina R., Gucek M., Cole R.N., Zachos N.C., Salahuddin F.F. et al.

Physiol. Genomics 43:674-684(2011) · Mapped (2)

Genome-wide analysis reveals the vacuolar pH-stat of Saccharomyces cerevisiae.

Brett C.L., Kallay L., Hua Z., Green R., Chyou A., Zhang Y., Graham T.R., Donowitz M., Rao R.

PLoS ONE 6:e17619-e17619(2011) · Mapped (12)

NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.

Sarker R., Valkhoff V.E., Zachos N.C., Lin R., Cha B., Chen T.E., Guggino S., Zizak M., de Jonge H., Hogema B. et al.

Am. J. Physiol., Cell Physiol. 300:C771-82(2011) · Mapped (8)

Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine.

Chen M., Sultan A., Cinar A., Yeruva S., Riederer B., Singh A.K., Li J., Bonhagen J., Chen G., Yun C. et al.

J. Physiol. (Lond.) 588:5049-5063(2010) · Mapped (5)

Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles.

Donowitz M., Singh S., Singh P., Salahuddin F.F., Chen Y., Chakraborty M., Murtazina R., Gucek M., Cole R.N., Zachos N.C. et al.

Physiol. Genomics 42A:200-210(2010) · Mapped (3)

Mutations in TTC37 cause trichohepatoenteric syndrome (phenotypic diarrhea of infancy).

Hartley J.L., Zachos N.C., Dawood B., Donowitz M., Forman J., Pollitt R.J., Morgan N.V., Tee L., Gissen P., Kahr W.H. et al.

Gastroenterology 138:2388-2398(2010) · UniProtKB (1)

Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.

Lin S., Yeruva S., He P., Singh A.K., Zhang H., Chen M., Lamprecht G., de Jonge H.R., Tse M., Donowitz M. et al.

Gastroenterology 138:649-658(2010) · Mapped (5)

NHERF3 (PDZK1) contributes to basal and calcium inhibition of NHE3 activity in Caco-2BBe cells.

Zachos N.C., Li X., Kovbasnjuk O., Hogema B., Sarker R., Lee L.J., Li M., de Jonge H., Donowitz M.

J. Biol. Chem. 284:23708-23718(2009) · Mapped (5)

Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Zachos N.C., van Rossum D.B., Li X., Caraveo G., Sarker R., Cha B., Mohan S., Desiderio S., Patterson R.L., Donowitz M.

J. Biol. Chem. 284:19437-19444(2009) · Mapped (3)

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.

Singh A.K., Riederer B., Krabbenhoft A., Rausch B., Bonhagen J., Lehmann U., de Jonge H.R., Donowitz M., Yun C., Weinman E.J. et al.

J. Clin. Invest. 119:540-550(2009) · Mapped (16)

Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.

Zachos N.C., Hodson C., Kovbasnjuk O., Li X., Thelin W.R., Cha B., Milgram S., Donowitz M.

Cell. Physiol. Biochem. 22:693-704(2008) · UniProtKB (4) · Mapped (2)

Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.

Broere N., Chen M., Cinar A., Singh A.K., Hillesheim J., Riederer B., Lunnemann M., Rottinghaus I., Krabbenhoft A., Engelhardt R. et al.

Pflugers Arch. 457:1079-1091(2009) · Mapped (3)

Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3.

Sarker R., Gronborg M., Cha B., Mohan S., Chen Y., Pandey A., Litchfield D., Donowitz M., Li X.

Mol. Biol. Cell 19:3859-3870(2008) · Mapped (8)

Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.

Cunningham R., Esmaili A., Brown E., Biswas R.S., Murtazina R., Donowitz M., Dijkman H.B., van der Vlag J., Hogema B.M., De Jonge H.R. et al.

Am. J. Physiol. Renal Physiol. 294:F1001-7(2008) · Mapped (5)

Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.

Broere N., Hillesheim J., Tuo B., Jorna H., Houtsmuller A.B., Shenolikar S., Weinman E.J., Donowitz M., Seidler U., de Jonge H.R. et al.

J. Biol. Chem. 282:37575-37584(2007) · Mapped (12)

Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.

Murtazina R., Kovbasnjuk O., Zachos N.C., Li X., Chen Y., Hubbard A., Hogema B.M., Steplock D., Seidler U., Hoque K.M. et al.

J. Biol. Chem. 282:25141-25151(2007) · Mapped (8)

ClC-5: role in endocytosis in the proximal tubule.

Wang Y., Cai H., Cebotaru L., Hryciw D.H., Weinman E.J., Donowitz M., Guggino S.E., Guggino W.B.

Am. J. Physiol. Renal Physiol. 289:F850-62(2005) · Mapped (6)

Evolutionary origins of eukaryotic sodium/proton exchangers.

Brett C.L., Donowitz M., Rao R.

Am. J. Physiol., Cell Physiol. 288:C223-39(2005) · Mapped (1)

NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway.

Jung Kang Y., Su Jeon E., Jin Lee H., Oh Y.S., Suh P.G., Sup Jung J., Donowitz M., Ho Kim J.

Cell. Signal. 16:791-800(2004) · Mapped (3)

Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: role in absorption and differentiation.

Li X., Leu S., Cheong A., Zhang H., Baibakov B., Shih C., Birnbaum M.J., Donowitz M.

Gastroenterology 126:122-135(2004) · Mapped (11)

Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling.

Mahon M.J., Donowitz M., Yun C.C., Segre G.V.

Nature 417:858-861(2002) · Mapped (7)

Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis.

Kim J.H., Lee-Kwon W., Park J.B., Ryu S.H., Yun C.H., Donowitz M.

J. Biol. Chem. 277:23714-23724(2002)

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