| Heterozygous deletion of Atbf1 by the Cre-loxP system in mice causes preweaning mortality. Sun X., Fu X., Li J., Xing C., Martin D.W., Zhang H.H., Chen Z., Dong J.T.
Genesis 50:819-827(2012) · Mapped (6) |
| Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP. Dong X.Y., Fu X., Fan S., Guo P., Su D., Dong J.T.
Biochem. J. 444:581-590(2012) · Mapped (3) |
| Down-regulation of leucine zipper putative tumor suppressor 1 is associated with poor prognosis, increased cell motility and invasion, and epithelial-to-mesenchymal transition characteristics in human breast carcinoma. Wang X.X., Zhu Z., Su D., Lei T., Wu X., Fan Y., Li X., Zhao J., Fu L., Dong J.T. et al.
Hum. Pathol. 42:1410-1419(2011) · Mapped (1) |
| Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cells. Dong X.Y., Guo P., Sun X., Li Q., Dong J.T.
J. Biol. Chem. 286:13879-13890(2011) · Mapped (61) |
| Opposing effects of KLF5 on the transcription of MYC in epithelial proliferation in the context of transforming growth factor beta. Guo P., Dong X.Y., Zhao K., Sun X., Li Q., Dong J.T.
J. Biol. Chem. 284:28243-28252(2009) · Mapped (22) |
| Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1. Zheng H.Q., Zhou Z., Huang J., Chaudhury L., Dong J.T., Chen C.
Oncogene 28:3702-3713(2009) · Mapped (7) |
| Estrogen-induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells. Guo P., Dong X.Y., Zhao K.W., Sun X., Li Q., Dong J.T.
Int. J. Cancer 126:81-89(2010) · Mapped (6) |
| Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases. Dong J.T., Chen C.
Cell. Mol. Life Sci. 66:2691-2706(2009) · Mapped (6) |
| Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells. Guo P., Zhao K.W., Dong X.Y., Sun X., Dong J.T.
J. Biol. Chem. 284:18184-18193(2009) · Mapped (18) |
| KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization. Liu R., Zheng H.Q., Zhou Z., Dong J.T., Chen C.
J. Biol. Chem. 284:16791-16798(2009) · Mapped (13) |
| Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma. Wang X.C., Wu Y.P., Ye B., Lin D.C., Feng Y.B., Zhang Z.Q., Xu X., Han Y.L., Cai Y., Dong J.T. et al.
Mol. Cancer Res. 7:12-22(2009) · Mapped (2) |
| Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. Guo P., Dong X.Y., Zhang X., Zhao K.W., Sun X., Li Q., Dong J.T.
J. Biol. Chem. 284:6071-6078(2009) · Mapped (13) |
| Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase. Liu M., Aneja R., Sun X., Xie S., Wang H., Wu X., Dong J.T., Li M., Joshi H.C., Zhou J.
J. Biol. Chem. 283:35783-35788(2008) · Mapped (24) |
| Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Guo L., Zhong D., Lau S., Liu X., Dong X.Y., Sun X., Yang V.W., Vertino P.M., Moreno C.S., Varma V. et al.
Mol. Cancer Res. 6:1421-1430(2008) · UniProtKB (2) · Mapped (1) |
| Down-regulation of tumor suppressor gene FEZ1/LZTS1 in breast carcinoma involves promoter methylation and associates with metastasis. Chen L., Zhu Z., Sun X., Dong X.Y., Wei J., Gu F., Sun Y.L., Zhou J., Dong J.T., Fu L.
Breast Cancer Res. Treat. 116:471-478(2009) · Mapped (1) |
| EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A. Sun L., Gao J., Dong X., Liu M., Li D., Shi X., Dong J.T., Lu X., Liu C., Zhou J.
Proc. Natl. Acad. Sci. U.S.A. 105:7153-7158(2008) · Mapped (10) |
| The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration. Gao J., Huo L., Sun X., Liu M., Li D., Dong J.T., Zhou J.
J. Biol. Chem. 283:8802-8809(2008) · UniProtKB (1) |
| Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma. Yang Y.L., Chu J.Y., Luo M.L., Wu Y.P., Zhang Y., Feng Y.B., Shi Z.Z., Xu X., Han Y.L., Cai Y. et al.
Genes Chromosomes Cancer 47:127-136(2008) · Mapped (3) |
| The amplified WWP1 gene is a potential molecular target in breast cancer. Chen C., Zhou Z., Ross J.S., Zhou W., Dong J.T.
Int. J. Cancer 121:80-87(2007) · Mapped (2) |
| Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway. Chen C., Zhou Z., Guo P., Dong J.T.
FEBS Lett. 581:1124-1130(2007) · Mapped (6) |
| Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer. Chen C., Sun X., Guo P., Dong X.Y., Sethi P., Zhou W., Zhou Z., Petros J., Frierson H.F. Jr., Vessella R.L. et al.
Oncogene 26:2386-2394(2007) · Mapped (2) |
| Infrequent mutation of ATBF1 in human breast cancer. Sun X., Zhou Y., Otto K.B., Wang M., Chen C., Zhou W., Subramanian K., Vertino P.M., Dong J.T.
J. Cancer Res. Clin. Oncol. 133:103-105(2007) · Mapped (3) |
| FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer. Dong X.Y., Chen C., Sun X., Guo P., Vessella R.L., Wang R.X., Chung L.W., Zhou W., Dong J.T.
Cancer Res. 66:6998-7006(2006) · Mapped (1) |
| Homozygous deletion of SMAD4 in breast cancer cell lines and invasive ductal carcinomas. Zhong D., Morikawa A., Guo L., Colpaert C., Xiong L., Nassar A., Chen C., Lamb N., Dong J.T., Zhou W.
Cancer Biol. Ther. 5:601-607(2006) · Mapped (2) |
| KLF5 Interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia. Zhu N., Gu L., Findley H.W., Chen C., Dong J.T., Yang L., Zhou M.
J. Biol. Chem. 281:14711-14718(2006) · Mapped (47) |
