1 - 25 of 93 results for author:"Donehower L.A." in Literature citations
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| MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. Donehower L.A., Creighton C.J., Schultz N., Shinbrot E., Chang K., Gunaratne P.H., Muzny D., Sander C., Hamilton S.R., Gibbs R.A. et al. J. Pathol. 229:99-110(2013) · Mapped (30) |
| Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses. Parikh N., Shuck R.L., Nguyen T.A., Herron A., Donehower L.A. Mol. Cancer Res. 10:845-855(2012) · Mapped (11) |
| Absence of Wip1 partially rescues Atm deficiency phenotypes in mice. Darlington Y., Nguyen T.A., Moon S.H., Herron A., Rao P., Zhu C., Lu X., Donehower L.A. Oncogene 31:1155-1165(2012) · Mapped (14) |
| Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. Terzian T., Dumble M., Arbab F., Thaller C., Donehower L.A., Lozano G., Justice M.J., Roop D.R., Box N.F. J. Pathol. 224:540-552(2011) · Mapped (19) |
| Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Gannon H.S., Donehower L.A., Lyle S., Jones S.N. Dev. Biol. 353:1-9(2011) · Mapped (23) |
| P53 genotype as a determinant of ER expression and tamoxifen response in the MMTV-Wnt-1 model of mammary carcinogenesis. Fuchs-Young R., Shirley S.H., Lambertz I., Colby J.K., Tian J., Johnston D., Gimenez-Conti I.B., Donehower L.A., Conti C.J., Hursting S.D. Breast Cancer Res. Treat. 130:399-408(2011) · Mapped (18) |
| Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma. Shang X., Vasudevan S.A., Yu Y., Ge N., Ludwig A.D., Wesson C.L., Wang K., Burlingame S.M., Zhao Y.J., Rao P.H. et al. Oncogene 29:4938-4946(2010) · Mapped (32) |
| Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. Lee S., Donehower L.A., Herron A.J., Moore D.D., Fu L. PLoS ONE 5:e10995-e10995(2010) · Mapped (38) |
| 55K isoform of CDK9 associates with Ku70 and is involved in DNA repair. Liu H., Herrmann C.H., Chiang K., Sung T.L., Moon S.H., Donehower L.A., Rice A.P. Biochem. Biophys. Res. Commun. 397:245-250(2010) · UniProtKB (2) · Mapped (7) |
| The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair. Nguyen T.A., Slattery S.D., Moon S.H., Darlington Y.F., Lu X., Donehower L.A. DNA Repair (Amst.) 9:813-823(2010) · Mapped (7) |
| Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Reddy J.P., Peddibhotla S., Bu W., Zhao J., Haricharan S., Du Y.C., Podsypanina K., Rosen J.M., Donehower L.A., Li Y. Proc. Natl. Acad. Sci. U.S.A. 107:3728-3733(2010) · Mapped (6) |
| Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. Moon S.H., Lin L., Zhang X., Nguyen T.A., Darlington Y., Waldman A.S., Lu X., Donehower L.A. J. Biol. Chem. 285:12935-12947(2010) · Mapped (64) |
| Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression. Hinkal G., Parikh N., Donehower L.A. PLoS ONE 4:e6654-e6654(2009) · Mapped (18) |
| Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging. Hinkal G.W., Gatza C.E., Parikh N., Donehower L.A. Mech. Ageing Dev. 130:262-271(2009) · Mapped (18) |
| MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression. Ma O., Cai W.W., Zender L., Dayaram T., Shen J., Herron A.J., Lowe S.W., Man T.K., Lau C.C., Donehower L.A. Cancer Res. 69:2559-2567(2009) · Mapped (11) |
| Notch signaling contributes to the pathogenesis of human osteosarcomas. Engin F., Bertin T., Ma O., Jiang M.M., Wang L., Sutton R.E., Donehower L.A., Lee B. Hum. Mol. Genet. 18:1464-1470(2009) · Mapped (5) |
| Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity. Moore L., Lu X., Ghebranious N., Tyner S., Donehower L.A. Mech. Ageing Dev. 128:717-730(2007) · Mapped (50) |
| Altered mammary gland development in the p53+/m mouse, a model of accelerated aging. Gatza C.E., Dumble M., Kittrell F., Edwards D.G., Dearth R.K., Lee A.V., Xu J., Medina D., Donehower L.A. Dev. Biol. 313:130-141(2008) · Mapped (18) |
| The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Lu X., Ma O., Nguyen T.A., Jones S.N., Oren M., Donehower L.A. Cancer Cell 12:342-354(2007) · Mapped (75) |
| Early development of histiocytic sarcomas in p53 knockout mice treated with N-bis(2-hydroxypropyl)nitrosamine. Hirata A., Tsukamoto T., Yamamoto M., Takasu S., Sakai H., Ban H., Yanai T., Masegi T., Donehower L.A., Tatematsu M. Oncol. Rep. 18:755-761(2007) · Mapped (18) |
| Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34. Abba M.C., Fabris V.T., Hu Y., Kittrell F.S., Cai W.W., Donehower L.A., Sahin A., Medina D., Aldaz C.M. Cancer Res. 67:4104-4112(2007) · Mapped (11) |
| The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Dumble M., Moore L., Chambers S.M., Geiger H., Van Zant G., Goodell M.A., Donehower L.A. Blood 109:1736-1742(2007) · Mapped (18) |
| DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse. Sommer M., Poliak N., Upadhyay S., Ratovitski E., Nelkin B.D., Donehower L.A., Sidransky D. Cell Cycle 5:2005-2011(2006) · Mapped (4) |
| Oxidative and nitrative stress caused by subcutaneous implantation of a foreign body accelerates sarcoma development in Trp53+/- mice. Tazawa H., Tatemichi M., Sawa T., Gilibert I., Ma N., Hiraku Y., Donehower L.A., Ohgaki H., Kawanishi S., Ohshima H. Carcinogenesis 28:191-198(2007) · Mapped (11) |
| Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Nannenga B., Lu X., Dumble M., Van Maanen M., Nguyen T.A., Sutton R., Kumar T.R., Donehower L.A. Mol. Carcinog. 45:594-604(2006) · Mapped (7) |