| Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes. Karamitri A., Shore A.M., Docherty K., Speakman J.R., Lomax M.A.
J. Biol. Chem. 284:20738-20752(2009) · Mapped (8) |
| Identification of adjacent binding sites for the YY1 and E4BP4 transcription factors in the ovine PrP (Prion) gene promoter. Burgess S.T., Shen C., Ferguson L.A., O'Neill G.T., Docherty K., Hunter N., Goldmann W.
J. Biol. Chem. 284:6716-6724(2009) · Mapped (24) |
| Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Bernardo A.S., Cho C.H., Mason S., Docherty H.M., Pedersen R.A., Vallier L., Docherty K.
Stem Cells 27:341-351(2009) · Mapped (1) |
| C/EBPbeta reprograms white 3T3-L1 preadipocytes to a Brown adipocyte pattern of gene expression. Karamanlidis G., Karamitri A., Docherty K., Hazlerigg D.G., Lomax M.A.
J. Biol. Chem. 282:24660-24669(2007) · Mapped (10) |
| ATF-2 stimulates the human insulin promoter through the conserved CRE2 sequence. Hay C.W., Ferguson L.A., Docherty K.
Biochim. Biophys. Acta 1769:79-91(2007) · Mapped (15) |
| Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP mouse. Bernardo A.S., Barrow J., Hay C.W., McCreath K., Kind A.J., Schnieke A.E., Colman A., Hart A.W., Docherty K.
Mol. Cell. Endocrinol. 253:14-21(2006) · Mapped (2) |
| Transcription factor cycling on the insulin promoter. Barrow J., Hay C.W., Ferguson L.A., Docherty H.M., Docherty K.
FEBS Lett. 580:711-715(2006) · Mapped (7) |
| Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family. Cockburn B.N., Bermano G., Boodram L.L., Teelucksingh S., Tsuchiya T., Mahabir D., Allan A.B., Stein R., Docherty K., Bell G.I.
J. Clin. Endocrinol. Metab. 89:971-978(2004) · Mapped (1) |
| Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function. McKinnon C.M., Docherty K.
Diabetologia 44:1203-1214(2001) · Mapped (2) |
| Sex steroid regulation of glutamate decarboxylase mRNA expression in goldfish brain is sexually dimorphic. Bosma P.T., Blazquez M., Fraser E.J., Schulz R.W., Docherty K., Trudeau V.L.
J. Neurochem. 76:945-956(2001) · UniProtKB (2) |
| Inhibitory effect of Pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters. Campbell S.C., Cragg H., Elrick L.J., Macfarlane W.M., Shennan K.I., Docherty K.
FEBS Lett. 463:53-57(1999) · UniProtKB (1) · Mapped (2) |
| Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes. Macfarlane W.M., Frayling T.M., Ellard S., Evans J.C., Allen L.I., Bulman M.P., Ayres S., Shepherd M., Clark P., Millward A. et al.
J. Clin. Invest. 104:R33-R39(1999) · UniProtKB (1) |
| Multiplicity of glutamic acid decarboxylases (GAD) in vertebrates: molecular phylogeny and evidence for a new GAD paralog. Bosma P.T., Blazquez M., Collins M.A., Bishop J.D., Drouin G., Priede I.G., Docherty K., Trudeau V.L.
Mol. Biol. Evol. 16:397-404(1999) · UniProtKB (12) |
| Gamma-aminobutyric acid up-regulates the expression of a novel secretogranin-II messenger ribonucleic acid in the goldfish pituitary. Blazquez M., Bosma P.T., Chang J.P., Docherty K., Trudeau V.L.
Endocrinology 139:4870-4880(1998) · UniProtKB (6) |
| The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells. Macfarlane W.M., Smith S.B., James R.F., Clifton A.D., Doza Y.N., Cohen P., Docherty K.
J. Biol. Chem. 272:20936-20944(1997) · UniProtKB (1) |
| Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells. Taylor N.A., Shennan K.I., Cutler D.F., Docherty K.
Biochem. J. 321:367-373(1997) |
| Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans. Gilligan M., Welsh G.I., Flynn A., Bujalska I., Diggle T.A., Denton R.M., Proud C.G., Docherty K.
J. Biol. Chem. 271:2121-2125(1996) |
| Synthesis and processing in vivo of the novel mouse thyrotropin beta-presubunit that contains an NH2-terminal extension sequence. Januszeski M.M., Gabriel J.L., Shennan K.I., Docherty K., Gurr J.A.
Endocrinology 134:1859-1867(1994) · Mapped (5) |
| Calcium- and pH-dependent aggregation and membrane association of the precursor of the prohormone convertase PC2. Shennan K.I., Taylor N.A., Docherty K.
J. Biol. Chem. 269:18646-18650(1994) |
| Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2. Bailyes E.M., Shennan K.I., Usac E.F., Arden S.D., Guest P.C., Docherty K., Hutton J.C.
Biochem. J. 309:587-594(1995) |
