1 - 25 of 87 results for author:"Dobson C.M." in Literature citations
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| Protease-activated alpha-2-macroglobulin can inhibit amyloid formation via two distinct mechanisms. Wyatt A.R., Constantinescu P., Ecroyd H., Dobson C.M., Wilson M.R., Kumita J.R., Yerbury J.J. FEBS Lett. 587:398-403(2013) · Mapped (2) |
| Expression in drosophila of tandem amyloid beta peptides provides insights into links between aggregation and neurotoxicity. Speretta E., Jahn T.R., Tartaglia G.G., Favrin G., Barros T.P., Imarisio S., Lomas D.A., Luheshi L.M., Crowther D.C., Dobson C.M. J. Biol. Chem. 287:20748-20754(2012) · Mapped (1) |
| The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila. Gregory J.M., Barros T.P., Meehan S., Dobson C.M., Luheshi L.M. PLoS ONE 7:e31899-e31899(2012) · Mapped (5) |
| The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-beta(1-40) peptide. Narayan P., Orte A., Clarke R.W., Bolognesi B., Hook S., Ganzinger K.A., Meehan S., Wilson M.R., Dobson C.M., Klenerman D. Nat. Struct. Mol. Biol. 19:79-83(2012) · Mapped (15) |
| Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility. De Simone A., Dhulesia A., Soldi G., Vendruscolo M., Hsu S.T., Chiti F., Dobson C.M. Proc. Natl. Acad. Sci. U.S.A. 108:21057-21062(2011) · Mapped (1) |
| Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid beta self-assembly. Abelein A., Bolognesi B., Dobson C.M., Graslund A., Lendel C. Biochemistry 51:126-137(2012) · Mapped (10) |
| Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster. Kumita J.R., Helmfors L., Williams J., Luheshi L.M., Menzer L., Dumoulin M., Lomas D.A., Crowther D.C., Dobson C.M., Brorsson A.C. FASEB J. 26:192-202(2012) · Mapped (5) |
| Conserved C-terminal charge exerts a profound influence on the aggregation rate of alpha-synuclein. Levitan K., Chereau D., Cohen S.I., Knowles T.P., Dobson C.M., Fink A.L., Anderson J.P., Goldstein J.M., Millhauser G.L. J. Mol. Biol. 411:329-333(2011) · Mapped (7) |
| Clusterin facilitates in vivo clearance of extracellular misfolded proteins. Wyatt A.R., Yerbury J.J., Berghofer P., Greguric I., Katsifis A., Dobson C.M., Wilson M.R. Cell. Mol. Life Sci. 68:3919-3931(2011) · UniProtKB (1) · Mapped (8) |
| Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I. Raimondi S., Guglielmi F., Giorgetti S., Di Gaetano S., Arciello A., Monti D.M., Relini A., Nichino D., Doglia S.M., Natalello A. et al. J. Mol. Biol. 407:465-476(2011) · Mapped (4) |
| Relationship between prion propensity and the rates of individual molecular steps of fibril assembly. Wang Y.Q., Buell A.K., Wang X.Y., Welland M.E., Dobson C.M., Knowles T.P., Perrett S. J. Biol. Chem. 286:12101-12107(2011) · Mapped (2) |
| Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants. Roodveldt C., Labrador-Garrido A., Gonzalez-Rey E., Fernandez-Montesinos R., Caro M., Lachaud C.C., Waudby C.A., Delgado M., Dobson C.M., Pozo D. PLoS ONE 5:e13481-e13481(2010) · Mapped (1) |
| Structure and properties of a complex of alpha-synuclein and a single-domain camelid antibody. De Genst E.J., Guilliams T., Wellens J., O'Day E.M., Waudby C.A., Meehan S., Dumoulin M., Hsu S.T., Cremades N., Verschueren K.H. et al. J. Mol. Biol. 402:326-343(2010) · Mapped (1) |
| ANS binding reveals common features of cytotoxic amyloid species. Bolognesi B., Kumita J.R., Barros T.P., Esbjorner E.K., Luheshi L.M., Crowther D.C., Wilson M.R., Dobson C.M., Favrin G., Yerbury J.J. ACS Chem. Biol. 5:735-740(2010) · Mapped (10) |
| Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. Luheshi L.M., Hoyer W., de Barros T.P., van Dijk Hard I., Brorsson A.C., Macao B., Persson C., Crowther D.C., Lomas D.A., Stahl S. et al. PLoS Biol. 8:e1000334-e1000334(2010) · Mapped (14) |
| Detergent-like interaction of Congo red with the amyloid beta peptide. Lendel C., Bolognesi B., Wahlstrom A., Dobson C.M., Graslund A. Biochemistry 49:1358-1360(2010) · Mapped (10) |
| Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy. Bodner C.R., Maltsev A.S., Dobson C.M., Bax A. Biochemistry 49:862-871(2010) · Mapped (7) |
| Methods and models in neurodegenerative and systemic protein aggregation diseases. Brorsson A.C., Kumita J.R., MacLeod I., Bolognesi B., Speretta E., Luheshi L.M., Knowles T.P., Dobson C.M., Crowther D.C. Front. Biosci. 15:373-396(2010) · Mapped (10) |
| An analytical solution to the kinetics of breakable filament assembly. Knowles T.P., Waudby C.A., Devlin G.L., Cohen S.I., Aguzzi A., Vendruscolo M., Terentjev E.M., Welland M.E., Dobson C.M. Science 326:1533-1537(2009) · Mapped (3) |
| Amyloidogenicity and aggregate cytotoxicity of human glucagon-like peptide-1 (hGLP-1). Poon S., Birkett N.R., Fowler S.B., Luisi B.F., Dobson C.M., Zurdo J. Protein Pept. Lett. 16:1548-1556(2009) · Mapped (1) |
| Towards multiparametric fluorescent imaging of amyloid formation: studies of a YFP model of alpha-synuclein aggregation. van Ham T.J., Esposito A., Kumita J.R., Hsu S.T., Kaminski Schierle G.S., Kaminski C.F., Dobson C.M., Nollen E.A., Bertoncini C.W. J. Mol. Biol. 395:627-642(2010) · Mapped (7) |
| Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip. Roodveldt C., Bertoncini C.W., Andersson A., van der Goot A.T., Hsu S.T., Fernandez-Montesinos R., de Jong J., van Ham T.J., Nollen E.A., Pozo D. et al. EMBO J. 28:3758-3770(2009) · Mapped (8) |
| Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. Yanamandra K., Alexeyev O., Zamotin V., Srivastava V., Shchukarev A., Brorsson A.C., Tartaglia G.G., Vogl T., Kayed R., Wingsle G. et al. PLoS ONE 4:e5562-e5562(2009) · Mapped (3) |
| Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation. Carulla N., Zhou M., Arimon M., Gairi M., Giralt E., Robinson C.V., Dobson C.M. Proc. Natl. Acad. Sci. U.S.A. 106:7828-7833(2009) · Mapped (10) |
| Structure, dynamics and folding of an immunoglobulin domain of the gelation factor (ABP-120) from Dictyostelium discoideum. Hsu S.T., Cabrita L.D., Fucini P., Dobson C.M., Christodoulou J. J. Mol. Biol. 388:865-879(2009) · Mapped (1) |