| Post-translational regulation of TGF-beta receptor and Smad signaling. Xu P., Liu J., Derynck R.
FEBS Lett. 586:1871-1884(2012) · Mapped (28) |
| TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association. Xu P., Liu J., Sakaki-Yumoto M., Derynck R.
Sci Signal 5:ra34-ra34(2012) · Mapped (12) |
| TGF-beta-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion. Lamouille S., Connolly E., Smyth J.W., Akhurst R.J., Derynck R.
J. Cell. Sci. 125:1259-1273(2012) · Mapped (5) |
| Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)-dependent TGF-beta signaling. Upadhyay G., Yin Y., Yuan H., Li X., Derynck R., Glazer R.I.
Proc. Natl. Acad. Sci. U.S.A. 108:7820-7825(2011) · Mapped (7) |
| Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-beta and Runx2 in bone is required for hearing. Chang J.L., Brauer D.S., Johnson J., Chen C.G., Akil O., Balooch G., Humphrey M.B., Chin E.N., Porter A.E., Butcher K. et al.
EMBO Rep. 11:765-771(2010) · Mapped (53) |
| Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation. Xu P., Derynck R.
Mol. Cell 37:551-566(2010) · UniProtKB (2) · Mapped (30) |
| Identification of the GATA factor TRPS1 as a repressor of the osteocalcin promoter. Piscopo D.M., Johansen E.B., Derynck R.
J. Biol. Chem. 284:31690-31703(2009) · Mapped (8) |
| Essential role of TGF-beta signaling in glucose-induced cell hypertrophy. Wu L., Derynck R.
Dev. Cell 17:35-48(2009) · Mapped (6) |
| TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling. Liu C., Xu P., Lamouille S., Xu J., Derynck R.
Mol. Cell 35:26-36(2009) · Mapped (23) |
| TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch. Liu I.M., Schilling S.H., Knouse K.A., Choy L., Derynck R., Wang X.F.
EMBO J. 28:88-98(2009) · Mapped (3) |
| Association of tetraspanin CD9 with transmembrane TGF{alpha} confers alterations in cell-surface presentation of TGF{alpha} and cytoskeletal organization. Imhof I., Gasper W.J., Derynck R.
J. Cell. Sci. 121:2265-2274(2008) · Mapped (13) |
| The type I TGF-beta receptor is covalently modified and regulated by sumoylation. Kang J.S., Saunier E.F., Akhurst R.J., Derynck R.
Nat. Cell Biol. 10:654-664(2008) · UniProtKB (1) · Mapped (13) |
| TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA. Lee M.K., Pardoux C., Hall M.C., Lee P.S., Warburton D., Qing J., Smith S.M., Derynck R.
EMBO J. 26:3957-3967(2007) · Mapped (5) |
| Cornichon regulates transport and secretion of TGFalpha-related proteins in metazoan cells. Perez Castro C., Piscopo D., Nakagawa T., Derynck R.
J. Cell Sci. 120:2454-2466(2007) · UniProtKB (4) · Mapped (18) |
| TGF-beta regulates the mechanical properties and composition of bone matrix. Balooch G., Balooch M., Nalla R.K., Schilling S., Filvaroff E.H., Marshall G.W., Marshall S.J., Ritchie R.O., Derynck R., Alliston T.
Proc. Natl. Acad. Sci. U.S.A. 102:18813-18818(2005) · Mapped (6) |
| Crystal structure of IRF-3 in complex with CBP. Qin B.Y., Liu C., Srinath H., Lam S.S., Correia J.J., Derynck R., Lin K.
Structure 13:1269-1277(2005) · UniProtKB (1) |
| Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3. Kang J.S., Alliston T., Delston R., Derynck R.
EMBO J. 24:2543-2555(2005) · Mapped (38) |
| Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands. Nakagawa T., Guichard A., Castro C.P., Xiao Y., Rizen M., Zhang H.-Z., Hu D., Bang A., Helms J., Bier E. et al.
Dev. Dyn. 233:1315-1331(2005) · UniProtKB (1) · Mapped (22) |
| Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1. Alliston T., Ko T.C., Cao Y., Liang Y.Y., Feng X.H., Chang C., Derynck R.
J. Biol. Chem. 280:24227-24237(2005) · Mapped (7) |
| Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation. Qin B.Y., Liu C., Lam S.S., Srinath H., Delston R., Correia J.J., Derynck R., Lin K.
Nat. Struct. Biol. 10:913-921(2003) · UniProtKB (1) |
| Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling. Lee P.S., Chang C., Liu D., Derynck R.
J. Biol. Chem. 278:27853-27863(2003) · Mapped (2) |
| Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide. Fan H., Turck C.W., Derynck R.
J. Biol. Chem. 278:18617-18627(2003) · UniProtKB (1) |
| Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. Choy L., Derynck R.
J. Biol. Chem. 278:9609-9619(2003) · Mapped (11) |
| Transforming growth factor-beta inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors. Li C., Zhu N.L., Tan R.C., Ballard P.L., Derynck R., Minoo P.
J. Biol. Chem. 277:38399-38408(2002) · Mapped (23) |
| TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Liu D., Black B.L., Derynck R.
Genes Dev. 15:2950-2966(2001) · Mapped (10) |
