| PDX-1 is a therapeutic target for pancreatic cancer, insulinoma and islet neoplasia using a novel RNA interference platform. Liu S.H., Rao D.D., Nemunaitis J., Senzer N., Zhou G., Dawson D., Gingras M.C., Wang Z., Gibbs R., Norman M. et al.
PLoS ONE 7:e40452-e40452(2012) · Mapped (1) |
| Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. Bisig C.G., Guiraldelli M.F., Kouznetsova A., Scherthan H., Hoog C., Dawson D.S., Pezza R.J.
PLoS Genet. 8:e1002701-e1002701(2012) · Mapped (3) |
| Thermal instability of DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) channel function: protection by single suppressor mutations and inhibiting channel activity. Liu X., O'Donnell N., Landstrom A., Skach W.R., Dawson D.C.
Biochemistry 51:5113-5124(2012) · Mapped (45) |
| Negative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5. Zhou G., Liu S.H., Shahi K.M., Wang H., Duan X., Lin X., Feng X.H., Li M., Fisher W.E., Demayo F.J. et al.
Mol. Endocrinol. 26:1225-1234(2012) · Mapped (5) |
| Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Mann K.M., Ward J.M., Yew C.C., Kovochich A., Dawson D.W., Black M.A., Brett B.T., Sheetz T.E., Dupuy A.J., Chang D.K. et al.
Proc. Natl. Acad. Sci. U.S.A. 109:5934-5941(2012) · Mapped (65) |
| Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore. Norimatsu Y., Ivetac A., Alexander C., Kirkham J., O'Donnell N., Dawson D.C., Sansom M.S.
Biochemistry 51:2199-2212(2012) · Mapped (45) |
| Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model. Gier B., Matveyenko A.V., Kirakossian D., Dawson D., Dry S.M., Butler P.C.
Diabetes 61:1250-1262(2012) · Mapped (5) |
| Wnt/beta-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Biechele T.L., Kulikauskas R.M., Toroni R.A., Lucero O.M., Swift R.D., James R.G., Robin N.C., Dawson D.W., Moon R.T., Chien A.J.
Sci Signal 5:ra3-ra3(2012) · Mapped (9) |
| Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein. Camp N.D., James R.G., Dawson D.W., Yan F., Davison J.M., Houck S.A., Tang X., Zheng N., Major M.B., Moon R.T.
J. Biol. Chem. 287:6539-6550(2012) · Mapped (9) |
| Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Zhou D., Zhang Y., Wu H., Barry E., Yin Y., Lawrence E., Dawson D., Willis J.E., Markowitz S.D., Camargo F.D. et al.
Proc. Natl. Acad. Sci. U.S.A. 108:E1312-20(2011) · Mapped (22) |
| Association of insulin and insulin-like growth factors with Barrett's oesophagus. Greer K.B., Thompson C.L., Brenner L., Bednarchik B., Dawson D., Willis J., Grady W.M., Falk G.W., Cooper G.S., Li L. et al.
Gut 61:665-672(2012) · Mapped (24) |
| Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer. Li A., King J., Moro A., Sugi M.D., Dawson D.W., Kaplan J., Li G., Lu X., Strieter R.M., Burdick M. et al.
Am. J. Pathol. 178:1340-1349(2011) · Mapped (4) |
| N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo. Angst E., Dawson D.W., Stroka D., Gloor B., Park J., Candinas D., Reber H.A., Hines O.J., Eibl G.
Surgery 149:614-624(2011) · Mapped (9) |
| Platelet receptor polymorphisms do not influence Staphylococcus aureus-platelet interactions or infective endocarditis. Daga S., Shepherd J.G., Callaghan J.G., Hung R.K., Dawson D.K., Padfield G.J., Hey S.Y., Cartwright R.A., Newby D.E., Fitzgerald J.R.
Microbes Infect. 13:216-225(2011) · Mapped (7) |
| Slk19p of Saccharomyces cerevisiae regulates anaphase spindle dynamics through two independent mechanisms. Havens K.A., Gardner M.K., Kamieniecki R.J., Dresser M.E., Dawson D.S.
Genetics 186:1247-1260(2010) · Mapped (7) |
| PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Hill R., Calvopina J.H., Kim C., Wang Y., Dawson D.W., Donahue T.R., Dry S., Wu H.
Cancer Res. 70:7114-7124(2010) · Mapped (11) |
| Variants in the melanocortin-1 receptor (MC1R) gene appear to be associated with increased dental care-related anxiety, increased fear of dental pain, and greater likelihood of dental care avoidance. Dawson D.V.
J Evid Based Dent Pract 10:169-171(2010) · Mapped (21) |
| Indicators of anxiety and depression in women with the fragile X premutation: assessment of a clinical sample. Lachiewicz A., Dawson D., Spiridigliozzi G., Cuccaro M., Lachiewicz M., McConkie-Rosell A.
J Intellect Disabil Res 54:597-610(2010) · Mapped (8) |
| HPV infection and EGFR activation/alteration in HIV-infected East African patients with conjunctival carcinoma. Yu J.J., Fu P., Pink J.J., Dawson D., Wasman J., Orem J., Mwanda W.O., Zhu H., Liang X., Guo Y. et al.
PLoS ONE 5:e10477-e10477(2010) · Mapped (19) |
| Preliminary evidence of an association between COL1A2 polymorphisms and dental fluorosis in a population with high fluoride exposure. Dawson D.V.
J Evid Based Dent Pract 10:96-98(2010) · Mapped (5) |
| Temporal characterization of homology-independent centromere coupling in meiotic prophase. Obeso D., Dawson D.S.
PLoS ONE 5:e10336-e10336(2010) · Mapped (4) |
| Meiotic cohesin promotes pairing of nonhomologous centromeres in early meiotic prophase. Bardhan A., Chuong H., Dawson D.S.
Mol. Biol. Cell 21:1799-1809(2010) · Mapped (8) |
| Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. Angst E., Dawson D.W., Nguyen A., Park J., Go V.L., Reber H.A., Hines O.J., Eibl G.
Pancreas 39:675-679(2010) · Mapped (9) |
| Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Zhao Y., Zhang X., Guda K., Lawrence E., Sun Q., Watanabe T., Iwakura Y., Asano M., Wei L., Yang Z. et al.
Proc. Natl. Acad. Sci. U.S.A. 107:2592-2597(2010) · Mapped (18) |
| Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors. Pham H., Chen M., Li A., King J., Angst E., Dawson D.W., Park J., Reber H.A., Hines O.J., Eibl G.
Pancreas 39:332-339(2010) · Mapped (5) |
