1 - 25 of 28 results for author:"Darnay B.G." in Literature citations
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| The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms. Paul P.K., Bhatnagar S., Mishra V., Srivastava S., Darnay B.G., Choi Y., Kumar A. Mol. Cell. Biol. 32:1248-1259(2012) · Mapped (4) |
| Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response. Wu C.Y., Kang H.Y., Yang W.L., Wu J., Jeong Y.S., Wang J., Chan C.H., Lee S.W., Zhang X., Lamothe B. et al. J. Biol. Chem. 286:30806-30815(2011) · Mapped (1) |
| NF-kappaB signal triggering and termination by tumor necrosis factor receptor 2. Rodriguez M., Cabal-Hierro L., Carcedo M.T., Iglesias J.M., Artime N., Darnay B.G., Lazo P.S. J. Biol. Chem. 286:22814-22824(2011) · Mapped (7) |
| Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice. Paul P.K., Gupta S.K., Bhatnagar S., Panguluri S.K., Darnay B.G., Choi Y., Kumar A. J. Cell Biol. 191:1395-1411(2010) · Mapped (1) |
| Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. Zhou X., Zhang Z., Feng J.Q., Dusevich V.M., Sinha K., Zhang H., Darnay B.G., de Crombrugghe B. Proc. Natl. Acad. Sci. U.S.A. 107:12919-12924(2010) · Mapped (3) |
| Structural basis for the lack of E2 interaction in the RING domain of TRAF2. Yin Q., Lamothe B., Darnay B.G., Wu H. Biochemistry 48:10558-10567(2009) · UniProtKB (1) · Mapped (2) |
| The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Yang W.-L., Wang J., Chan C.-H., Lee S.-W., Campos A.D., Lamothe B., Hur L., Grabiner B.C., Lin X., Darnay B.G. et al. |
| A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains. Duwel M., Welteke V., Oeckinghaus A., Baens M., Kloo B., Ferch U., Darnay B.G., Ruland J., Marynen P., Krappmann D. J. Immunol. 182:7718-7728(2009) · UniProtKB (1) · Mapped (22) |
| E2 interaction and dimerization in the crystal structure of TRAF6. Yin Q., Lin S.C., Lamothe B., Lu M., Lo Y.C., Hura G., Zheng L., Rich R.L., Campos A.D., Myszka D.G. et al. Nat. Struct. Mol. Biol. 16:658-666(2009) · UniProtKB (1) · Mapped (1) |
| Hypoxia-associated factor, a novel E3-ubiquitin ligase, binds and ubiquitinates hypoxia-inducible factor 1alpha, leading to its oxygen-independent degradation. Koh M.Y., Darnay B.G., Powis G. Mol. Cell. Biol. 28:7081-7095(2008) · Mapped (13) |
| Cthrc1 is a positive regulator of osteoblastic bone formation. Kimura H., Kwan K.M., Zhang Z., Deng J.M., Darnay B.G., Behringer R.R., Nakamura T., de Crombrugghe B., Akiyama H. PLoS ONE 3:e3174-e3174(2008) · Mapped (20) |
| TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1. Ning S., Campos A.D., Darnay B.G., Bentz G.L., Pagano J.S. Mol. Cell. Biol. 28:6536-6546(2008) · Mapped (6) |
| The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL. Lamothe B., Campos A.D., Webster W.K., Gopinathan A., Hur L., Darnay B.G. J. Biol. Chem. 283:24871-24880(2008) · Mapped (17) |
| Association between imatinib-resistant BCR-ABL mutation-negative leukemia and persistent activation of LYN kinase. Wu J., Meng F., Kong L.Y., Peng Z., Ying Y., Bornmann W.G., Darnay B.G., Lamothe B., Sun H., Talpaz M. et al. J. Natl. Cancer Inst. 100:926-939(2008) · UniProtKB (1) · Mapped (3) |
| Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20. Lin S.C., Chung J.Y., Lamothe B., Rajashankar K., Lu M., Lo Y.C., Lam A.Y., Darnay B.G., Wu H. J. Mol. Biol. 376:526-540(2008) · UniProtKB (1) · Mapped (20) |
| Nuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modification. Pham L.V., Zhou H.J., Lin-Lee Y.C., Tamayo A.T., Yoshimura L.C., Fu L., Darnay B.G., Ford R.J. J. Biol. Chem. 283:5081-5089(2008) · UniProtKB (3) · Mapped (29) |
| Receptor activator of nuclear factor-kappaB ligand-induced nuclear factor of activated T cells (C1) autoregulates its own expression in osteoclasts and mediates the up-regulation of tartrate-resistant acid phosphatase. Fretz J.A., Shevde N.K., Singh S., Darnay B.G., Pike J.W. Mol. Endocrinol. 22:737-750(2008) · Mapped (12) |
| TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation. Lamothe B., Webster W.K., Gopinathan A., Besse A., Campos A.D., Darnay B.G. Biochem. Biophys. Res. Commun. 359:1044-1049(2007) · Mapped (12) |
| Inhibition of RANKL-mediated osteoclast differentiation by selective TRAF6 decoy peptides. Poblenz A.T., Jacoby J.J., Singh S., Darnay B.G. Biochem. Biophys. Res. Commun. 359:510-515(2007) · Mapped (1) |
| CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation. Grabiner B.C., Blonska M., Lin P.C., You Y., Wang D., Sun J., Darnay B.G., Dong C., Lin X. Genes Dev. 21:984-996(2007) · Mapped (4) |
| Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways. Shambharkar P.B., Blonska M., Pappu B.P., Li H., You Y., Sakurai H., Darnay B.G., Hara H., Penninger J., Lin X. EMBO J. 26:1794-1805(2007) · Mapped (13) |
| TAK1-dependent signaling requires functional interaction with TAB2/TAB3. Besse A., Lamothe B., Campos A.D., Webster W.K., Maddineni U., Lin S.C., Wu H., Darnay B.G. J. Biol. Chem. 282:3918-3928(2007) · Mapped (14) |
| Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. Lamothe B., Besse A., Campos A.D., Webster W.K., Wu H., Darnay B.G. J. Biol. Chem. 282:4102-4112(2007) · UniProtKB (3) · Mapped (5) |
| TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor. Polek T.C., Talpaz M., Darnay B.G., Spivak-Kroizman T. J. Biol. Chem. 278:32317-32323(2003) · Mapped (5) |
| Distinct molecular mechanism for initiating TRAF6 signalling. Ye H., Arron J.R., Lamothe B., Cirilli M., Kobayashi T., Shevde N.K., Segal D., Dzivenu O.K., Vologodskaia M., Yim M. et al. |