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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Sidransky E., Nalls M.A., Aasly J.O., Aharon-Peretz J., Annesi G., Barbosa E.R., Bar-Shira A., Berg D., Bras J., Brice A. et al.

N. Engl. J. Med. 361:1651-1661(2009) · Mapped (11)

Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens.

Wilkinson P., Waterfield N.R., Crossman L., Corton C., Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L., Ormond D. et al.

BMC Genomics 10:302-302(2009) · UniProtKB (1)

Mutations in the Parkinson's disease genes, Leucine Rich Repeat Kinase 2 (LRRK2) and Glucocerebrosidase (GBA), are not associated with essential tremor.

Clark L.N., Kisselev S., Park N., Ross B., Verbitsky M., Rios E., Alcalay R.N., Lee J.H., Louis E.D.

Parkinsonism Relat. Disord. 0:0-0(2009) · Mapped (15)

Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain.

Seth-Smith H.M.B., Harris S.R., Persson K., Marsh P., Barron A., Bignell A., Bjartling C., Clark L., Cutcliffe L.T., Lambden P.R. et al.

BMC Genomics 10:239-239(2009) · UniProtKB (1,773)

Association of glucocerebrosidase mutations with dementia with lewy bodies.

Clark L.N., Kartsaklis L.A., Wolf Gilbert R., Dorado B., Ross B.M., Kisselev S., Verbitsky M., Mejia-Santana H., Cote L.J., Andrews H. et al.

Arch. Neurol. 66:578-583(2009) · Mapped (17)

Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis.

Ward P.N., Holden M.T.G., Leigh J.A., Lennard N., Bignell A., Barron A., Clark L., Quail M.A., Woodward J., Barrell B.G. et al.

BMC Genomics 10:54-54(2009) · UniProtKB (1,760)

Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse.

Sachadyn P., Zhang X.M., Clark L.D., Naviaux R.K., Heber-Katz E.

Mitochondrion 8:358-366(2008) · UniProtKB (13)

Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella gallinarum 287/91 provides insights into evolutionary and host adaptation pathways.

Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S., Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M. et al.

Genome Res. 18:1624-1637(2008) · UniProtKB (8,151)

Risk of Parkinson disease in carriers of parkin mutations: estimation using the kin-cohort method.

Wang Y., Clark L.N., Louis E.D., Mejia-Santana H., Harris J., Cote L.J., Waters C., Andrews H., Ford B., Frucht S. et al.

Arch. Neurol. 65:467-474(2008) · Mapped (14)

Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation.

Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G. et al.

J. Bacteriol. 190:2150-2160(2008) · UniProtKB (3,057)

Association between genetic variants in SORL1 and autopsy-confirmed Alzheimer disease.

Lee J.H., Cheng R., Honig L.S., Vonsattel J.P., Clark L., Mayeux R.

Neurology 70:887-889(2008) · Mapped (5)

Mutations in the glucocerebrosidase gene are associated with early-onset Parkinson disease.

Clark L.N., Ross B.M., Wang Y., Mejia-Santana H., Harris J., Louis E.D., Cote L.J., Andrews H., Fahn S., Waters C. et al.

Neurology 69:1270-1277(2007) · Mapped (11)

Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene.

Clark L.N., Haamer E., Mejia-Santana H., Harris J., Lesage S., Durr A., Bs S.J., Hedrich K., Louis E.D., Cote L.J. et al.

Mov. Disord. 22:932-937(2007) · Mapped (14)

Frequency of LRRK2 mutations in early- and late-onset Parkinson disease.

Clark L.N., Wang Y., Karlins E., Saito L., Mejia-Santana H., Harris J., Louis E.D., Cote L.J., Andrews H., Fahn S. et al.

Neurology 67:1786-1791(2006) · Mapped (4)

The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention.

Roiser J.P., Muller U., Clark L., Sahakian B.J.

Int. J. Neuropsychopharmacol. 10:449-461(2007) · Mapped (4)

Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome.

Ikonomidis J.S., Jones J.A., Barbour J.R., Stroud R.E., Clark L.L., Kaplan B.S., Zeeshan A., Bavaria J.E., Gorman J.H., Spinale F.G. et al.

Circulation 114:I365-70(2006) · Mapped (2)

Macrophage's proinflammatory response to a mycobacterial infection is dependent on sphingosine kinase-mediated activation of phosphatidylinositol phospholipase C, protein kinase C, ERK1/2, and phosphatidylinositol 3-kinase.

Yadav M., Clark L., Schorey J.S.

J. Immunol. 176:5494-5503(2006) · Mapped (6)

Case-control study of the parkin gene in early-onset Parkinson disease.

Clark L.N., Afridi S., Karlins E., Wang Y., Mejia-Santana H., Harris J., Louis E.D., Cote L.J., Andrews H., Fahn S. et al.

Arch. Neurol. 63:548-552(2006) · Mapped (14)

Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design.

Clark L.A., Boriack-Sjodin P.A., Eldredge J., Fitch C., Friedman B., Hanf K.J., Jarpe M., Liparoto S.F., Li Y., Lugovskoy A. et al.

Protein Sci. 15:949-960(2006) · Mapped (2)

Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion.

Roiser J.P., Blackwell A.D., Cools R., Clark L., Rubinsztein D.C., Robbins T.W., Sahakian B.J.

Neuropsychopharmacology 31:2264-2272(2006) · Mapped (4)

Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity.

Clark L., Roiser J.P., Cools R., Rubinsztein D.C., Sahakian B.J., Robbins T.W.

Psychopharmacology (Berl.) 182:570-578(2005) · Mapped (4)

Sense and antisense transcripts of the apolipoprotein E gene in normal and ApoE knockout mice, their expression after spinal cord injury and corresponding human transcripts.

Seitz A., Gourevitch D., Zhang X.M., Clark L., Chen P., Kragol M., Levenkova N., Rux J., Samulewicz S., Heber-Katz E.

Hum. Mol. Genet. 14:2661-2670(2005) · Mapped (9)

The genome of the African trypanosome Trypanosoma brucei.

Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B. et al.

Science 309:416-422(2005) · UniProtKB (4,402)

Extensive DNA inversions in the B. fragilis genome control variable gene expression.

Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A. et al.

Science 307:1463-1465(2005) · UniProtKB (4,234)

Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18.

Pickard B.S., Malloy M.P., Clark L., Lehellard S., Ewald H.L., Mors O., Porteous D.J., Blackwood D.H., Muir W.J.

Psychiatr. Genet. 15:37-44(2005) · UniProtKB (1)

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