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Literature citations Results

Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes.

Tugues S., Roche F., Noguer O., Orlova A., Bhoi S., Padhan N., Akerud P., Honjo S., Selvaraju R.K., Mazzone M. et al.

PLoS ONE 9:e107483-e107483(2014) · Mapped (5)

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.

Bentley K., Franco C.A., Philippides A., Blanco R., Dierkes M., Gebala V., Stanchi F., Jones M., Aspalter I.M., Cagna G. et al.

Nat. Cell Biol. 16:309-321(2014) · Mapped (5)

Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period.

Yao L.C., Testini C., Tvorogov D., Anisimov A., Vargas S.O., Baluk P., Pytowski B., Claesson-Welsh L., Alitalo K., McDonald D.M.

Circ. Res. 114:806-822(2014) · Mapped (3)

Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-beta1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial cells in vitro and in vivo.

Tugues S., Honjo S., Konig C., Padhan N., Kroon J., Gualandi L., Li X., Barkefors I., Thijssen V.L., Griffioen A.W. et al.

J. Biol. Chem. 288:19060-19071(2013) · UniProtKB (2) · Mapped (5)

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.

Hayashi M., Majumdar A., Li X., Adler J., Sun Z., Vertuani S., Hellberg C., Mellberg S., Koch S., Dimberg A. et al.

Nat Commun 4:1672-1672(2013) · Mapped (7)

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling.

Lanner F., Lee K.L., Ortega G.C., Sohl M., Li X., Jin S., Hansson E.M., Claesson-Welsh L., Poellinger L., Lendahl U. et al.

Stem Cells Dev. 22:1360-1369(2013) · Mapped (1)

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

Sun Z., Li X., Massena S., Kutschera S., Padhan N., Gualandi L., Sundvold-Gjerstad V., Gustafsson K., Choy W.W., Zang G. et al.

J. Exp. Med. 209:1363-1377(2012) · Mapped (6)

Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization.

Tugues S., Honjo S., Konig C., Noguer O., Hedlund M., Botling J., Deschoemaeker S., Wenes M., Rolny C., Jahnen-Dechent W. et al.

Cancer Res. 72:1953-1963(2012) · UniProtKB (1) · Mapped (1)

Blood vessels as targets in tumor therapy.

Claesson-Welsh L.

Ups. J. Med. Sci. 117:178-186(2012) · Mapped (2)

Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis.

Le Jan S., Hayashi M., Kasza Z., Eriksson I., Bishop J.R., Weibrecht I., Heldin J., Holmborn K., Jakobsson L., Soderberg O. et al.

Arterioscler. Thromb. Vasc. Biol. 32:1255-1263(2012) · Mapped (7)

Signal transduction by vascular endothelial growth factor receptors.

Koch S., Tugues S., Li X., Gualandi L., Claesson-Welsh L.

Biochem. J. 437:169-183(2011) · UniProtKB (3)

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

Rolny C., Mazzone M., Tugues S., Laoui D., Johansson I., Coulon C., Squadrito M.L., Segura I., Li X., Knevels E. et al.

Cancer Cell 19:31-44(2011) · UniProtKB (2) · Mapped (7)

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression.

Geretti E., van Meeteren L.A., Shimizu A., Dudley A.C., Claesson-Welsh L., Klagsbrun M.

Mol. Cancer Res. 8:1063-1073(2010) · Mapped (11)

p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration.

Li Z., Zhang H., Lundin L., Thullberg M., Liu Y., Wang Y., Claesson-Welsh L., Stromblad S.

J. Biol. Chem. 285:23699-23710(2010) · UniProtKB (1) · Mapped (3)

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease.

Van de Veire S., Stalmans I., Heindryckx F., Oura H., Tijeras-Raballand A., Schmidt T., Loges S., Albrecht I., Jonckx B., Vinckier S. et al.

Cell 141:178-190(2010) · Mapped (8)

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

Berge T., Sundvold-Gjerstad V., Granum S., Andersen T.C., Holthe G.B., Claesson-Welsh L., Andreotti A.H., Inngjerdingen M., Spurkland A.

PLoS ONE 5:e9761-e9761(2010) · Mapped (30)

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

Hagberg C.E., Falkevall A., Wang X., Larsson E., Huusko J., Nilsson I., van Meeteren L.A., Samen E., Lu L., Vanwildemeersch M. et al.

Nature 464:917-921(2010) · Mapped (10)

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.

Nilsson I., Bahram F., Li X., Gualandi L., Koch S., Jarvius M., Soderberg O., Anisimov A., Kholova I., Pytowski B. et al.

EMBO J. 29:1377-1388(2010) · UniProtKB (2) · Mapped (37)

Distinct role of PLCbeta3 in VEGF-mediated directional migration and vascular sprouting.

Bhattacharya R., Kwon J., Li X., Wang E., Patra S., Bida J.P., Bajzer Z., Claesson-Welsh L., Mukhopadhyay D.

J. Cell. Sci. 122:1025-1034(2009) · Mapped (1)

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis.

Mellberg S., Dimberg A., Bahram F., Hayashi M., Rennel E., Ameur A., Westholm J.O., Larsson E., Lindahl P., Cross M.J. et al.

FASEB J. 23:1490-1502(2009) · UniProtKB (2) · Mapped (18)

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization.

Kawamura H., Li X., Goishi K., van Meeteren L.A., Jakobsson L., Cebe-Suarez S., Shimizu A., Edholm D., Ballmer-Hofer K., Kjellen L. et al.

Blood 112:3638-3649(2008) · Mapped (2)

Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity.

Kawamura H., Li X., Harper S.J., Bates D.O., Claesson-Welsh L.

Cancer Res. 68:4683-4692(2008) · Mapped (1)

Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow.

Jakobsson L., Domogatskaya A., Tryggvason K., Edgar D., Claesson-Welsh L.

FASEB J. 22:1530-1539(2008) · Mapped (4)

alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis.

Dimberg A., Rylova S., Dieterich L.C., Olsson A.K., Schiller P., Wikner C., Bohman S., Botling J., Lukinius A., Wawrousek E.F. et al.

Blood 111:2015-2023(2008) · Mapped (7)

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin.

Magnusson P.U., Dimberg A., Mellberg S., Lukinius A., Claesson-Welsh L.

Blood 110:4214-4222(2007) · Mapped (13)

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