| The adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation. Yoo S.M., Antonyak M.A., Cerione R.A.
J. Biol. Chem. 287:31462-31470(2012) · Mapped (7) |
| The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5). Zhou Y., Zhang H., He B., Du J., Lin H., Cerione R.A., Hao Q.
J. Biol. Chem. 287:28307-28314(2012) · Mapped (3) |
| Characterization of a novel activated Ran GTPase mutant and its ability to induce cellular transformation. Milano S.K., Kwon W., Pereira R., Antonyak M.A., Cerione R.A.
J. Biol. Chem. 287:24955-24966(2012) · Mapped (5) |
| Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation. Basso M., Berlin J., Xia L., Sleiman S.F., Ko B., Haskew-Layton R., Kim E., Antonyak M.A., Cerione R.A., Iismaa S.E. et al.
J. Neurosci. 32:6561-6569(2012) · Mapped (3) |
| A constitutively active Galpha subunit provides insights into the mechanism of G protein activation. Singh G., Ramachandran S., Cerione R.A.
Biochemistry 51:3232-3240(2012) · Mapped (2) |
| Tissue transglutaminase and its role in human cancer progression. Li B., Cerione R.A., Antonyak M.
Adv. Enzymol. Relat. Areas Mol. Biol. 78:247-293(2011) · Mapped (8) |
| Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Du J., Zhou Y., Su X., Yu J.J., Khan S., Jiang H., Kim J., Woo J., Kim J.H., Choi B.H. et al.
Science 334:806-809(2011) · UniProtKB (9) · Mapped (3) |
| Glutaminase: a hot spot for regulation of cancer cell metabolism? Erickson J.W., Cerione R.A.
Oncotarget 1:734-740(2010) · Mapped (9) |
| Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. McConoughey S.J., Basso M., Niatsetskaya Z.V., Sleiman S.F., Smirnova N.A., Langley B.C., Mahishi L., Cooper A.J., Antonyak M.A., Cerione R.A. et al.
EMBO Mol Med 2:349-370(2010) · Mapped (3) |
| Phosphorylation of the cool-1/beta-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells. Feng Q., Baird D., Yoo S., Antonyak M., Cerione R.A.
J. Biol. Chem. 285:18806-18816(2010) · Mapped (4) |
| EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation. Li B., Antonyak M.A., Druso J.E., Cheng L., Nikitin A.Y., Cerione R.A.
Proc. Natl. Acad. Sci. U.S.A. 107:1408-1413(2010) · Mapped (15) |
| Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation. Ly T.K., Wang J., Pereira R., Rojas K.S., Peng X., Feng Q., Cerione R.A., Wilson K.F.
J. Biol. Chem. 285:5815-5826(2010) · Mapped (5) |
| The molecular basis for the regulation of the cap-binding complex by the importins. Dias S.M., Wilson K.F., Rojas K.S., Ambrosio A.L., Cerione R.A.
Nat. Struct. Mol. Biol. 16:930-937(2009) · Mapped (7) |
| Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion. Antonyak M.A., Li B., Regan A.D., Feng Q., Dusaban S.S., Cerione R.A.
J. Biol. Chem. 284:17914-17925(2009) · Mapped (11) |
| Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation. Endo M., Antonyak M.A., Cerione R.A.
J. Biol. Chem. 284:5107-5118(2009) · Mapped (18) |
| Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Peng X., Wu X., Druso J.E., Wei H., Park A.Y., Kraus M.S., Alcaraz A., Chen J., Chien S., Cerione R.A. et al.
Proc. Natl. Acad. Sci. U.S.A. 105:6638-6643(2008) · Mapped (48) |
| Effector proteins exert an important influence on the signaling-active state of the small GTPase Cdc42. Phillips M.J., Calero G., Chan B., Ramachandran S., Cerione R.A.
J. Biol. Chem. 283:14153-14164(2008) · Mapped (6) |
| Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. DeRegis C.J., Rahl P.B., Hoffman G.R., Cerione R.A., Collins R.N.
BMC Cell Biol. 9:3-3(2008) · Mapped (2) |
| GTP-binding-defective forms of tissue transglutaminase trigger cell death. Datta S., Antonyak M.A., Cerione R.A.
Biochemistry 46:14819-14829(2007) · Mapped (8) |
| X-ray crystal structures reveal two activated states for RhoC. Dias S.M., Cerione R.A.
Biochemistry 46:6547-6558(2007) · Mapped (5) |
| Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42. Lin Q., Yang W., Baird D., Feng Q., Cerione R.A.
J. Biol. Chem. 281:35253-35262(2006) · UniProtKB (4) · Mapped (2) |
| Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Feng Q., Baird D., Peng X., Wang J., Ly T., Guan J.L., Cerione R.A.
Nat. Cell Biol. 8:945-956(2006) · Mapped (2) |
| Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42. Fidyk N., Wang J.B., Cerione R.A.
Biochemistry 45:7750-7762(2006) · Mapped (3) |
| A Cdc42 mutant specifically activated by intersectin. Smith W.J., Hamel B., Yohe M.E., Sondek J., Cerione R.A., Snyder J.T.
Biochemistry 44:13282-13290(2005) · Mapped (6) |
| Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. Wang J.B., Wu W.J., Cerione R.A.
J. Biol. Chem. 280:22883-22891(2005) · Mapped (42) |
