1 - 25 of
93
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for author:"Cantley L.C."
in Literature Citations
| Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Hill J.W., Xu Y., Preitner F., Fukuda M., Cho Y.R., Luo J., Balthasar N., Coppari R., Cantley L.C., Kahn B.B. et al. Endocrinology 150:4874-4882(2009) · Mapped (10) |
| Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Mouta-Bellum C., Kirov A., Miceli-Libby L., Mancini M.L., Petrova T.V., Liaw L., Prudovsky I., Thorpe P.E., Miura N., Cantley L.C. et al. Dev. Dyn. 238:2670-2679(2009) · Mapped (23) |
| Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Gewinner C., Wang Z.C., Richardson A., Teruya-Feldstein J., Etemadmoghadam D., Bowtell D., Barretina J., Lin W.M., Rameh L., Salmena L. et al. Cancer Cell 16:115-125(2009) · Mapped (6) |
| Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation. Hutti J.E., Shen R.R., Abbott D.W., Zhou A.Y., Sprott K.M., Asara J.M., Hahn W.C., Cantley L.C. Mol. Cell 34:461-472(2009) · Mapped (4) |
| Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Schweitzer M.H., Zheng W., Organ C.L., Avci R., Suo Z., Freimark L.M., Lebleu V.S., Duncan M.B., Vander Heiden M.G., Neveu J.M. et al. Science 324:626-631(2009) · UniProtKB (2) |
| PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer. Ogino S., Nosho K., Kirkner G.J., Shima K., Irahara N., Kure S., Chan A.T., Engelman J.A., Kraft P., Cantley L.C. et al. J. Clin. Oncol. 27:1477-1484(2009) · Mapped (40) |
| Bidirectional transport of amino acids regulates mTOR and autophagy. Nicklin P., Bergman P., Zhang B., Triantafellow E., Wang H., Nyfeler B., Yang H., Hild M., Kung C., Wilson C. et al. Cell 136:521-534(2009) · Mapped (8) |
| Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Engelman J.A., Chen L., Tan X., Crosby K., Guimaraes A.R., Upadhyay R., Maira M., McNamara K., Perera S.A., Song Y. et al. Nat. Med. 14:1351-1356(2008) · Mapped (18) |
| Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. Carracedo A., Ma L., Teruya-Feldstein J., Rojo F., Salmena L., Alimonti A., Egia A., Sasaki A.T., Thomas G., Kozma S.C. et al. J. Clin. Invest. 118:3065-3074(2008) · Mapped (5) |
| Class 1A PI3K regulates vessel integrity during development and tumorigenesis. Yuan T.L., Choi H.S., Matsui A., Benes C., Lifshits E., Luo J., Frangioni J.V., Cantley L.C. Proc. Natl. Acad. Sci. U.S.A. 105:9739-9744(2008) · Mapped (11) |
| Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. Hill J.W., Williams K.W., Ye C., Luo J., Balthasar N., Coppari R., Cowley M.A., Cantley L.C., Lowell B.B., Elmquist J.K. J. Clin. Invest. 118:1796-1805(2008) · Mapped (12) |
| Pyruvate kinase M2 is a phosphotyrosine-binding protein. Christofk H.R., Vander Heiden M.G., Wu N., Asara J.M., Cantley L.C. Nature 452:181-186(2008) · Mapped (10) |
| Interpreting sequences from mastodon and T. rex. Asara J.M., Garavelli J.S., Slatter D.A., Schweitzer M.H., Freimark L.M., Phillips M., Cantley L.C. Science 317:1324-1325(2007) · UniProtKB (4) |
| IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway. Hutti J.E., Turk B.E., Asara J.M., Ma A., Cantley L.C., Abbott D.W. Mol. Cell. Biol. 27:7451-7461(2007) · Mapped (10) |
| Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains. Abbott D.W., Yang Y., Hutti J.E., Madhavarapu S., Kelliher M.A., Cantley L.C. Mol. Cell. Biol. 27:6012-6025(2007) · Mapped (33) |
| Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis. Chang J.D., Sukhova G.K., Libby P., Schvartz E., Lichtenstein A.H., Field S.J., Kennedy C., Madhavarapu S., Luo J., Wu D. et al. Proc. Natl. Acad. Sci. U.S.A. 104:8077-8082(2007) · Mapped (13) |
| MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Engelman J.A., Zejnullahu K., Mitsudomi T., Song Y., Hyland C., Park J.O., Lindeman N., Gale C.M., Zhao X., Christensen J. et al. Science 316:1039-1043(2007) · Mapped (36) |
| Protein sequences from Mastodon and Tyrannosaurus rex revealed by mass spectrometry. Asara J.M., Schweitzer M.H., Freimark L.M., Phillips M., Cantley L.C. Science 316:280-285(2007) · UniProtKB (4) |
| Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo. Hurov J.B., Huang M., White L.S., Lennerz J., Choi C.S., Cho Y.R., Kim H.J., Prior J.L., Piwnica-Worms D., Cantley L.C. et al. Proc. Natl. Acad. Sci. U.S.A. 104:5680-5685(2007) · Mapped (5) |
| Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. Holt L.J., Hutti J.E., Cantley L.C., Morgan D.O. Mol. Cell 25:689-702(2007) · Mapped (10) |
| The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance. Taniguchi C.M., Aleman J.O., Ueki K., Luo J., Asano T., Kaneto H., Stephanopoulos G., Cantley L.C., Kahn C.R. Mol. Cell. Biol. 27:2830-2840(2007) · Mapped (13) |
| T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. Deane J.A., Kharas M.G., Oak J.S., Stiles L.N., Luo J., Moore T.I., Ji H., Rommel C., Cantley L.C., Lane T.E. et al. Blood 109:2894-2902(2007) · Mapped (7) |
| Sjogren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase. Oak J.S., Deane J.A., Kharas M.G., Luo J., Lane T.E., Cantley L.C., Fruman D.A. Proc. Natl. Acad. Sci. U.S.A. 103:16882-16887(2006) · Mapped (7) |
| Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN. Taniguchi C.M., Tran T.T., Kondo T., Luo J., Ueki K., Cantley L.C., Kahn C.R. Proc. Natl. Acad. Sci. U.S.A. 103:12093-12097(2006) · Mapped (8) |
| Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia. Luo J., Sobkiw C.L., Hirshman M.F., Logsdon M.N., Li T.Q., Goodyear L.J., Cantley L.C. Cell Metab. 3:355-366(2006) · Mapped (10) |
