| STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration. Jin L., Getahun A., Knowles H.M., Mogan J., Akerlund L.J., Packard T.A., Perraud A.L., Cambier J.C.
J. Immunol. 190:2835-2843(2013) · Mapped (1) |
| Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Clambey E.T., McNamee E.N., Westrich J.A., Glover L.E., Campbell E.L., Jedlicka P., de Zoeten E.F., Cambier J.C., Stenmark K.R., Colgan S.P. et al.
Proc. Natl. Acad. Sci. U.S.A. 109:E2784-93(2012) · Mapped (8) |
| Retention of anergy and inhibition of antibody responses during acute gamma herpesvirus 68 infection. Getahun A., Smith M.J., Kogut I., van Dyk L.F., Cambier J.C.
J. Immunol. 189:2965-2974(2012) · Mapped (17) |
| B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity. Khalil A.M., Cambier J.C., Shlomchik M.J.
Science 336:1178-1181(2012) · Mapped (11) |
| The inositol 5-phosphatase SHIP-1 and adaptors Dok-1 and 2 play central roles in CD4-mediated inhibitory signaling. Waterman P.M., Marschner S., Brandl E., Cambier J.C.
Immunol. Lett. 143:122-130(2012) · Mapped (7) |
| VISA is required for B cell expression of TLR7. Xu L.G., Jin L., Zhang B.C., Akerlund L.J., Shu H.B., Cambier J.C.
J. Immunol. 188:248-258(2012) · Mapped (2) |
| Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. O'Neill S.K., Getahun A., Gauld S.B., Merrell K.T., Tamir I., Smith M.J., Dal Porto J.M., Li Q.Z., Cambier J.C.
Immunity 35:746-756(2011) · Mapped (11) |
| MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP. Jin L., Hill K.K., Filak H., Mogan J., Knowles H., Zhang B., Perraud A.L., Cambier J.C., Lenz L.L.
J. Immunol. 187:2595-2601(2011) · Mapped (6) |
| Differential STIM1 expression in T and B cell subsets suggests a role in determining antigen receptor signal amplitude. Yarkoni Y., Cambier J.C.
Mol. Immunol. 48:1851-1858(2011) · Mapped (2) |
| A dose-dependent role for EBF1 in repressing non-B-cell-specific genes. Lukin K., Fields S., Guerrettaz L., Straign D., Rodriguez V., Zandi S., Mansson R., Cambier J.C., Sigvardsson M., Hagman J.
Eur. J. Immunol. 41:1787-1793(2011) · Mapped (14) |
| Identification and characterization of a loss-of-function human MPYS variant. Jin L., Xu L.G., Yang I.V., Davidson E.J., Schwartz D.A., Wurfel M.M., Cambier J.C.
Genes Immun. 12:263-269(2011) · Mapped (1) |
| Cellular reactive oxygen species inhibit MPYS induction of IFNbeta. Jin L., Lenz L.L., Cambier J.C.
PLoS ONE 5:e15142-e15142(2010) · Mapped (7) |
| CD23-mediated cell signaling in human B cells differs from signaling in cells of the monocytic lineage. Chan M.A., Gigliotti N.M., Matangkasombut P., Gauld S.B., Cambier J.C., Rosenwasser L.J.
Clin. Immunol. 137:330-336(2010) · Mapped (4) |
| TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23. Jackson L., Cady C.T., Cambier J.C.
J. Immunol. 183:2585-2592(2009) · Mapped (13) |
| Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells. O'Neill S.K., Veselits M.L., Zhang M., Labno C., Cao Y., Finnegan A., Uccellini M., Alegre M.L., Cambier J.C., Clark M.R.
Proc. Natl. Acad. Sci. U.S.A. 106:6262-6267(2009) · Mapped (1) |
| FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation. Crowley J.E., Stadanlick J.E., Cambier J.C., Cancro M.P.
Blood 113:1464-1473(2009) · Mapped (11) |
| MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals. Jin L., Waterman P.M., Jonscher K.R., Short C.M., Reisdorph N.A., Cambier J.C.
Mol. Cell. Biol. 28:5014-5026(2008) · UniProtKB (1) |
| Cutting Edge: Acute and chronic exposure of immature B cells to antigen leads to impaired homing and SHIP1-dependent reduction in stromal cell-derived factor-1 responsiveness. Brauweiler A., Merrell K., Gauld S.B., Cambier J.C.
J. Immunol. 178:3353-3357(2007) · Mapped (4) |
| Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding. Powell M.S., Barnes N.C., Bradford T.M., Musgrave I.F., Wines B.D., Cambier J.C., Hogarth P.M.
J. Immunol. 176:7489-7494(2006) · Mapped (2) |
| Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: activation without engagement of an inhibitory signaling pathway. Lyubchenko T., dal Porto J., Cambier J.C., Holers V.M.
J. Immunol. 174:3264-3272(2005) · Mapped (12) |
| Src-family kinases in B-cell development and signaling. Gauld S.B., Cambier J.C.
Oncogene 23:8001-8006(2004) · UniProtKB (2) |
| Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap. Isnardi I., Lesourne R., Bruhns P., Fridman W.H., Cambier J.C., Daeeron M.
J. Biol. Chem. 279:51931-51938(2004) · UniProtKB (2) · Mapped (6) |
| Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck. Dal Porto J.M., Burke K., Cambier J.C.
Immunity 21:443-453(2004) · Mapped (4) |
| Cognate B cell signaling via MHC class II: differential regulation of B cell antigen receptor and MHC class II/Ig-alpha beta signaling by CD22. Mills D.M., Stolpa J.C., Cambier J.C.
J. Immunol. 172:195-201(2004) · Mapped (7) |
| Ligation of human CD4 interferes with antigen-induced activation of primary T cells. Marschner S., Hunig T., Cambier J.C., Finkel T.H.
Immunol. Lett. 82:131-139(2002) · Mapped (4) |
