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Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma.

Bobic S., Seys S., De Vooght V., Callebaut I., Hox V., Dooms C., Vinckier S., Jonckx B., Saint-Remy J.M., Stassen J.M. et al.

Am. J. Respir. Cell Mol. Biol. 46:781-789(2012) · Mapped (1)

Functional analysis of the NUP98-CCDC28A fusion protein.

Petit A., Ragu C., Soler G., Ottolenghi C., Schluth C., Radford-Weiss I., Schneider-Maunoury S., Callebaut I., Dastugue N., Drabkin H.A. et al.

Haematologica 97:379-387(2012) · Mapped (7)

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.

Ropars V., Drevet P., Legrand P., Baconnais S., Amram J., Faure G., Marquez J.A., Pietrement O., Guerois R., Callebaut I. et al.

Proc. Natl. Acad. Sci. U.S.A. 108:12663-12668(2011) · Mapped (3)

The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane.

Elstak E.D., Neeft M., Nehme N.T., Voortman J., Cheung M., Goodarzifard M., Gerritsen H.C., van Bergen En Henegouwen P.M., Callebaut I., de Saint Basile G. et al.

Blood 118:1570-1578(2011) · Mapped (5)

The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein.

Op de Beeck K., Van Camp G., Thys S., Cools N., Callebaut I., Vrijens K., Van Nassauw L., Van Tendeloo V.F., Timmermans J.P., Van Laer L.

Eur. J. Hum. Genet. 19:965-973(2011) · UniProtKB (1) · Mapped (3)

Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF.

Malivert L., Ropars V., Nunez M., Drevet P., Miron S., Faure G., Guerois R., Mornon J.P., Revy P., Charbonnier J.B. et al.

J. Biol. Chem. 285:26475-26483(2010) · Mapped (1)

Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndrome.

Touzot F., Callebaut I., Soulier J., Gaillard L., Azerrad C., Durandy A., Fischer A., de Villartay J.P., Revy P.

Proc. Natl. Acad. Sci. U.S.A. 107:10097-10102(2010) · UniProtKB (1)

C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation.

Billet A., Melin P., Jollivet M., Mornon J.P., Callebaut I., Becq F.

J. Biol. Chem. 285:22132-22140(2010) · Mapped (45)

LOTUS, a new domain associated with small RNA pathways in the germline.

Callebaut I., Mornon J.P.

Bioinformatics 26:1140-1144(2010) · UniProtKB (3) · Mapped (1)

Molecular models of the open and closed states of the whole human CFTR protein.

Mornon J.P., Lehn P., Callebaut I.

Cell. Mol. Life Sci. 66:3469-3486(2009) · Mapped (45)

Dombrock genotyping in a native Congolese cohort reveals two novel alleles.

Chapel-Fernandes S., Callebaut I., Halverson G.R., Reid M.E., Bailly P., Chiaroni J.

Transfusion 49:1661-1671(2009) · UniProtKB (2) · Mapped (9)

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

Malivert L., Callebaut I., Rivera-Munoz P., Fischer A., Mornon J.P., Revy P., de Villartay J.P.

Mol. Cell. Biol. 29:1116-1122(2009) · Mapped (8)

A histidine in the beta-CASP domain of Artemis is critical for its full in vitro and in vivo functions.

de Villartay J.P., Shimazaki N., Charbonnier J.B., Fischer A., Mornon J.P., Lieber M.R., Callebaut I.

DNA Repair (Amst.) 8:202-208(2009) · Mapped (4)

3D mapping of glycogenosis-causing mutations in the large regulatory alpha subunit of phosphorylase kinase.

Carriere C., Jonic S., Mornon J.P., Callebaut I.

Biochim. Biophys. Acta 1782:664-670(2008) · Mapped (1)

Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces.

Mornon J.P., Lehn P., Callebaut I.

Cell. Mol. Life Sci. 65:2594-2612(2008) · Mapped (45)

Human mismatch repair protein MSH6 contains a PWWP domain that targets double stranded DNA.

Laguri C., Duband-Goulet I., Friedrich N., Axt M., Belin P., Callebaut I., Gilquin B., Zinn-Justin S., Couprie J.

Biochemistry 47:6199-6207(2008) · Mapped (7)

Multiple pathways inhibit NHEJ at telomeres.

Marcand S., Pardo B., Gratias A., Cahun S., Callebaut I.

Genes Dev. 22:1153-1158(2008) · Mapped (4)

The thyroid hormone-inactivating deiodinase functions as a homodimer.

Sagar G.D., Gereben B., Callebaut I., Mornon J.P., Zeold A., Curcio-Morelli C., Harney J.W., Luongo C., Mulcahey M.A., Larsen P.R. et al.

Mol. Endocrinol. 22:1382-1393(2008) · UniProtKB (1) · Mapped (1)

Atypical structure and phylogenomic evolution of the new eutherian oocyte-and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family.

Pierre A., Gautier M., Callebaut I., Bontoux M., Jeanpierre E., Pontarotti P., Monget P.

Genomics 90:583-594(2007) · UniProtKB (8) · Mapped (6)

The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA.

Lancelot N., Charier G., Couprie J., Duband-Goulet I., Alpha-Bazin B., Quemeneur E., Ma E., Marsolier-Kergoat M.C., Ropars V., Charbonnier J.B. et al.

Nucleic Acids Res. 35:5898-5912(2007) · Mapped (2)

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity.

Sagar G.D., Gereben B., Callebaut I., Mornon J.P., Zeold A., da Silva W.S., Luongo C., Dentice M., Tente S.M., Freitas B.C. et al.

Mol. Cell. Biol. 27:4774-4783(2007) · Mapped (6)

Bromodomain testis-specific protein is expressed in mouse oocyte and evolves faster than its ubiquitously expressed paralogs BRD2, -3, and -4.

Paillisson A., Levasseur A., Gouret P., Callebaut I., Bontoux M., Pontarotti P., Monget P.

Genomics 89:215-223(2007) · UniProtKB (1) · Mapped (1)

The discovery of SycO highlights a new function for type III secretion effector chaperones.

Letzelter M., Sorg I., Mota L.J., Meyer S., Stalder J., Feldman M., Kuhn M., Callebaut I., Cornelis G.R.

EMBO J. 25:3223-3233(2006) · Mapped (2)

A new Rubisco-like protein coexists with a photosynthetic Rubisco in the planktonic cyanobacteria Microcystis.

Carre-Mlouka A., Mejean A., Quillardet P., Ashida H., Saito Y., Yokota A., Callebaut I., Sekowska A., Dittmann E., Bouchier C. et al.

J. Biol. Chem. 281:24462-24471(2006) · UniProtKB (4)

ACCA phosphopeptide recognition by the BRCT repeats of BRCA1.

Ray H., Moreau K., Dizin E., Callebaut I., Venezia N.D.

J. Mol. Biol. 359:973-982(2006) · UniProtKB (2)

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