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Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.

Boumis G., Giardina G., Angelucci F., Bellelli A., Brunori M., Dimastrogiovanni D., Saccoccia F., Miele A.E.

Biochem. Biophys. Res. Commun. 425:806-811(2012) · Mapped (1)

Structure of nucleophosmin DNA-binding domain and analysis of its complex with a G-quadruplex sequence from the c-MYC promoter.

Gallo A., Lo Sterzo C., Mori M., Di Matteo A., Bertini I., Banci L., Brunori M., Federici L.

J. Biol. Chem. 287:26539-26548(2012) · Mapped (4)

Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin.

Saccoccia F., Di Micco P., Boumis G., Brunori M., Koutris I., Miele A.E., Morea V., Sriratana P., Williams D.L., Bellelli A. et al.

Structure 20:429-439(2012) · UniProtKB (1)

Structural and functional characterization of Schistosoma mansoni Thioredoxin.

Boumis G., Angelucci F., Bellelli A., Brunori M., Dimastrogiovanni D., Miele A.E.

Protein Sci. 20:1069-1076(2011) · UniProtKB (1)

Nucleophosmin C-terminal leukemia-associated domain interacts with G-rich quadruplex forming DNA.

Federici L., Arcovito A., Scaglione G.L., Scaloni F., Lo Sterzo C., Di Matteo A., Falini B., Giardina B., Brunori M.

J. Biol. Chem. 285:37138-37149(2010) · Mapped (4)

Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography.

Angelucci F., Dimastrogiovanni D., Boumis G., Brunori M., Miele A.E., Saccoccia F., Bellelli A.

J. Biol. Chem. 285:32557-32567(2010) · UniProtKB (1) · Mapped (1)

Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus.

Di Matteo A., Calosci N., Gianni S., Jemth P., Brunori M., Travaglini-Allocatelli C.

Proteins 78:2213-2221(2010) · Mapped (1)

Deciphering the folding transition state structure and denatured state properties of nucleophosmin C-terminal domain.

Scaloni F., Federici L., Brunori M., Gianni S.

Proc. Natl. Acad. Sci. U.S.A. 107:5447-5452(2010) · Mapped (4)

MDR1 C3435T polymorphism indicates a different outcome in advanced multiple myeloma.

Buda G., Martino A., Maggini V., Orciuolo E., Galimberti S., Gentile M., Morabito F., Antognoni F., Brunori M., Barale R. et al.

Acta Haematol. 122:42-45(2009) · Mapped (9)

Combining crystallography and molecular dynamics: the case of Schistosoma mansoni phospholipid glutathione peroxidase.

Dimastrogiovanni D., Anselmi M., Miele A.E., Boumis G., Petersson L., Angelucci F., Nola A.D., Brunori M., Bellelli A.

Proteins 78:259-270(2010) · Mapped (1)

Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.

Angelucci F., Sayed A.A., Williams D.L., Boumis G., Brunori M., Dimastrogiovanni D., Miele A.E., Pauly F., Bellelli A.

J. Biol. Chem. 284:28977-28985(2009) · UniProtKB (1)

Pattern of cavities in globins: the case of human hemoglobin.

Savino C., Miele A.E., Draghi F., Johnson K.A., Sciara G., Brunori M., Vallone B.

Biopolymers 91:1097-1107(2009) · Mapped (3)

Folding mechanism of the C-terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance.

Scaloni F., Gianni S., Federici L., Falini B., Brunori M.

FASEB J. 23:2360-2365(2009) · Mapped (4)

Serum C-reactive protein at diagnosis and response to therapy is the most powerful factor predicting outcome of multiple myeloma treated with thalidomide/ anthracycline-based therapy.

Offidani M., Corvatta L., Polloni C., Piersantelli M.N., Galieni P., Visani G., Alesiani F., Catarini M., Brunori M., Burattini M. et al.

Clin Lymphoma Myeloma 8:294-299(2008) · Mapped (17)

NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR.

Giardina G., Rinaldo S., Johnson K.A., Di Matteo A., Brunori M., Cutruzzola F.

J. Mol. Biol. 378:1002-1015(2008) · UniProtKB (1)

Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase.

Angelucci F., Miele A.E., Boumis G., Dimastrogiovanni D., Brunori M., Bellelli A.

Proteins 72:936-945(2008) · UniProtKB (1)

The O2-scavenging flavodiiron protein in the human parasite Giardia intestinalis.

Di Matteo A., Scandurra F.M., Testa F., Forte E., Sarti P., Brunori M., Giuffre A.

J. Biol. Chem. 283:4061-4068(2008) · UniProtKB (1)

A strategic protein in cytochrome c maturation: three-dimensional structure of CcmH and binding to apocytochrome c.

Di Matteo A., Gianni S., Schinina M.E., Giorgi A., Altieri F., Calosci N., Brunori M., Travaglini-Allocatelli C.

J. Biol. Chem. 282:27012-27019(2007) · Mapped (1)

The three-dimensional structure of two redox states of cyclophilin A from Schistosoma mansoni. Evidence for redox regulation of peptidyl-prolyl cis-trans isomerase activity.

Gourlay L.J., Angelucci F., Baiocco P., Boumis G., Brunori M., Bellelli A., Miele A.E.

J. Biol. Chem. 282:24851-24857(2007) · Mapped (1)

Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering.

Gianni S., Walma T., Arcovito A., Calosci N., Bellelli A., Engstrom A., Travaglini-Allocatelli C., Brunori M., Jemth P., Vuister G.W.

Structure 14:1801-1809(2006) · Mapped (2)

The structure of the endoribonuclease XendoU: from small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication.

Renzi F., Caffarelli E., Laneve P., Bozzoni I., Brunori M., Vallone B.

Proc. Natl. Acad. Sci. U.S.A. 103:12365-12370(2006) · UniProtKB (1)

Probing the mechanism of GSH activation in Schistosoma haematobium glutathione-S-transferase by site-directed mutagenesis and X-ray crystallography.

Baiocco P., Gourlay L.J., Angelucci F., Fontaine J., Herve M., Miele A.E., Trottein F., Brunori M., Bellelli A.

J. Mol. Biol. 360:678-689(2006) · UniProtKB (1)

The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair.

Lenain C., Bauwens S., Amiard S., Brunori M., Giraud-Panis M.J., Gilson E.

Curr. Biol. 16:1303-1310(2006) · UniProtKB (2)

Large-scale purification and crystallization of the endoribonuclease XendoU: troubleshooting with His-tagged proteins.

Renzi F., Panetta G., Vallone B., Brunori M., Arceci M., Bozzoni I., Laneve P., Caffarelli E.

Acta Crystallogr. F 62:298-301(2006) · UniProtKB (1)

Unveiling a hidden folding intermediate in c-type cytochromes by protein engineering.

Borgia A., Bonivento D., Travaglini-Allocatelli C., Di Matteo A., Brunori M.

J. Biol. Chem. 281:9331-9336(2006) · Mapped (1)

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