1 - 25 of 58 results for author:"Brown J.H." in Literature citations
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| APJ acts as a dual receptor in cardiac hypertrophy. Scimia M.C., Hurtado C., Ray S., Metzler S., Wei K., Wang J., Woods C.E., Purcell N.H., Catalucci D., Akasaka T. et al. Nature 488:394-398(2012) · Mapped (5) |
| CaMKIIdeltaC slows [Ca]i decline in cardiac myocytes by promoting Ca sparks. Guo T., Zhang T., Ginsburg K.S., Mishra S., Brown J.H., Bers D.M. Biophys. J. 102:2461-2470(2012) · Mapped (7) |
| Crystal structure of a phosphorylated light chain domain of scallop smooth-muscle myosin. Kumar V.S., O'Neall-Hennessey E., Reshetnikova L., Brown J.H., Robinson H., Szent-Gyorgyi A.G., Cohen C. Biophys. J. 101:2185-2189(2011) · UniProtKB (3) |
| A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function. Sadayappan S., Gulick J., Osinska H., Barefield D., Cuello F., Avkiran M., Lasko V.M., Lorenz J.N., Maillet M., Martin J.L. et al. Circ. Res. 109:141-150(2011) · Mapped (6) |
| Overexpression of CaMKIIdeltac in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality. Dybkova N., Sedej S., Napolitano C., Neef S., Rokita A.G., Hunlich M., Brown J.H., Kockskamper J., Priori S.G., Pieske B. et al. J. Am. Coll. Cardiol. 57:469-479(2011) · Mapped (7) |
| Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Brown J.H., Kumar V.S., O'Neall-Hennessey E., Reshetnikova L., Robinson H., Nguyen-McCarty M., Szent-Gyorgyi A.G., Cohen C. Proc. Natl. Acad. Sci. U.S.A. 108:114-119(2011) · UniProtKB (3) |
| Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. Elrod J.W., Wong R., Mishra S., Vagnozzi R.J., Sakthievel B., Goonasekera S.A., Karch J., Gabel S., Farber J., Force T. et al. J. Clin. Invest. 120:3680-3687(2010) · Mapped (1) |
| MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. Zhang D., Contu R., Latronico M.V., Zhang J., Zhang J.L., Rizzi R., Catalucci D., Miyamoto S., Huang K., Ceci M. et al. J. Clin. Invest. 120:2805-2816(2010) · Mapped (5) |
| PHLPP-1 negatively regulates Akt activity and survival in the heart. Miyamoto S., Purcell N.H., Smith J.M., Gao T., Whittaker R., Huang K., Castillo R., Glembotski C.C., Sussman M.A., Newton A.C. et al. Circ. Res. 107:476-484(2010) · Mapped (1) |
| Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling. Mishra S., Ling H., Grimm M., Zhang T., Bers D.M., Brown J.H. J. Cardiovasc. Pharmacol. 56:598-603(2010) · Mapped (3) |
| Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Borillo G.A., Mason M., Quijada P., Volkers M., Cottage C., McGregor M., Din S., Fischer K., Gude N., Avitabile D. et al. Circ. Res. 106:1265-1274(2010) · Mapped (7) |
| Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis. Carretero-Ortega J., Walsh C.T., Hernandez-Garcia R., Reyes-Cruz G., Brown J.H., Vazquez-Prado J. Mol. Pharmacol. 77:435-442(2010) · Mapped (1) |
| Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Zhang T., Guo T., Mishra S., Dalton N.D., Kranias E.G., Peterson K.L., Bers D.M., Brown J.H. Circ. Res. 106:354-362(2010) · Mapped (8) |
| beta-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes. Mani S.K., Egan E.A., Addy B.K., Grimm M., Kasiganesan H., Thiyagarajan T., Renaud L., Brown J.H., Kern C.B., Menick D.R. J. Mol. Cell. Cardiol. 48:342-351(2010) · Mapped (31) |
| Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Sag C.M., Wadsack D.P., Khabbazzadeh S., Abesser M., Grefe C., Neumann K., Opiela M.K., Backs J., Olson E.N., Brown J.H. et al. Circ Heart Fail 2:664-675(2009) · Mapped (3) |
| Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17. Catalucci D., Latronico M.V., Ceci M., Rusconi F., Young H.S., Gallo P., Santonastasi M., Bellacosa A., Brown J.H., Condorelli G. J. Biol. Chem. 284:28180-28187(2009) · Mapped (4) |
| Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death. Diwan A., Matkovich S.J., Yuan Q., Zhao W., Yatani A., Brown J.H., Molkentin J.D., Kranias E.G., Dorn G.W. J. Clin. Invest. 119:203-212(2009) · Mapped (4) |
| An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. Sheikh F., Raskin A., Chu P.H., Lange S., Domenighetti A.A., Zheng M., Liang X., Zhang T., Yajima T., Gu Y. et al. J. Clin. Invest. 118:3870-3880(2008) · Mapped (8) |
| Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection. Del Re D.P., Miyamoto S., Brown J.H. J. Biol. Chem. 283:35622-35629(2008) · Mapped (8) |
| Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61. Walsh C.T., Radeff-Huang J., Matteo R., Hsiao A., Subramaniam S., Stupack D., Brown J.H. FASEB J. 22:4011-4021(2008) · Mapped (23) |
| Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation. Haga J.H., Kaunas R., Radeff-Huang J., Weems J.M., Estrada K.D., Chien S., Brown J.H., Seasholtz T.M. Biochem. Biophys. Res. Commun. 372:216-220(2008) · Mapped (2) |
| S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses. Means C.K., Miyamoto S., Chun J., Brown J.H. J. Biol. Chem. 283:11954-11963(2008) · Mapped (7) |
| An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins. Brown J.H., Yang Y., Reshetnikova L., Gourinath S., Suveges D., Kardos J., Hobor F., Reutzel R., Nyitray L., Cohen C. J. Mol. Biol. 375:1434-1443(2008) · Mapped (2) |
| CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses. Zhang T., Kohlhaas M., Backs J., Mishra S., Phillips W., Dybkova N., Chang S., Ling H., Bers D.M., Maier L.S. et al. J. Biol. Chem. 282:35078-35087(2007) · UniProtKB (2) · Mapped (3) |
| Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation. Citro S., Malik S., Oestreich E.A., Radeff-Huang J., Kelley G.G., Smrcka A.V., Brown J.H. Proc. Natl. Acad. Sci. U.S.A. 104:15543-15548(2007) · Mapped (2) |