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Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress.

Miramon P., Dunker C., Windecker H., Bohovych I.M., Brown A.J., Kurzai O., Hube B.

PLoS ONE 7:E52850-E52850(2012) · UniProtKB (2)

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses.

Combating Swine Influenza Initiative-COSI Consortium
Lycett S.J., Baillie G., Coulter E., Bhatt S., Kellam P., McCauley J.W., Wood J.L., Brown I.H., Pybus O.G., Leigh Brown A.J.

J. Gen. Virol. 93:2326-2336(2012) · UniProtKB (956)

Protein kinase A modulates the activity of a major human isoform of ABCG1.

Gelissen I.C., Sharpe L.J., Sandoval C., Rao G., Kockx M., Kritharides L., Jessup W., Brown A.J.

J. Lipid Res. 53:2133-2140(2012) · Mapped (2)

Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans.

Mayer F.L., Wilson D., Jacobsen I.D., Miramon P., Slesiona S., Bohovych I.M., Brown A.J., Hube B.

PLoS ONE 7:e38584-e38584(2012)

Origin and fate of A/H1N1 influenza in Scotland during 2009.

Lycett S., McLeish N.J., Robertson C., Carman W., Baillie G., McMenamin J., Rambaut A., Simmonds P., Woolhouse M., Leigh Brown A.J.

J. Gen. Virol. 93:1253-1260(2012) · UniProtKB (834)

Distribution and regulation of the 25-hydroxyvitamin D3 1alpha-hydroxylase in human parathyroid glands.

Ritter C.S., Haughey B.H., Armbrecht H.J., Brown A.J.

J. Steroid Biochem. Mol. Biol. 130:73-80(2012) · Mapped (5)

Differential signaling by splice variants of the human free fatty acid receptor GPR120.

Watson S.J., Brown A.J., Holliday N.D.

Mol. Pharmacol. 81:631-642(2012) · Mapped (2)

The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1).

Zerenturk E.J., Kristiana I., Gill S., Brown A.J.

Biochim. Biophys. Acta 1821:1269-1277(2012) · Mapped (7)

Akt acutely activates the cholesterogenic transcription factor SREBP-2.

Luu W., Sharpe L.J., Stevenson J., Brown A.J.

Biochim. Biophys. Acta 1823:458-464(2012) · Mapped (10)

Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis.

Fei W., Li H., Shui G., Kapterian T.S., Bielby C., Du X., Brown A.J., Li P., Wenk M.R., Liu P. et al.

J. Lipid Res. 52:2136-2147(2011) · Mapped (3)

Transmission network parameters estimated from HIV sequences for a nationwide epidemic.

Leigh Brown A.J., Lycett S.J., Weinert L., Hughes G.J., Fearnhill E., Dunn D.T.

J. Infect. Dis. 204:1463-1469(2011) · UniProtKB (1,288)

Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.

Coopman K., Wallis R., Robb G., Brown A.J., Wilkinson G.F., Timms D., Willars G.B.

Mol. Endocrinol. 25:1804-1818(2011) · Mapped (1)

Norovirus RNA-dependent RNA polymerase is phosphorylated by an important survival kinase, Akt.

Eden J.S., Sharpe L.J., White P.A., Brown A.J.

J. Virol. 85:10894-10898(2011) · Mapped (5)

A role for phosphatidic acid in the formation of "supersized" lipid droplets.

Fei W., Shui G., Zhang Y., Krahmer N., Ferguson C., Kapterian T.S., Lin R.C., Dawes I.W., Brown A.J., Li P. et al.

PLoS Genet. 7:e1002201-e1002201(2011) · Mapped (16)

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils.

Balenga N.A., Aflaki E., Kargl J., Platzer W., Schroder R., Blattermann S., Kostenis E., Brown A.J., Heinemann A., Waldhoer M.

Cell Res. 21:1452-1469(2011) · Mapped (4)

Recognition and blocking of innate immunity cells by Candida albicans chitin.

Mora-Montes H.M., Netea M.G., Ferwerda G., Lenardon M.D., Brown G.D., Mistry A.R., Kullberg B.J., O'Callaghan C.A., Sheth C.C., Odds F.C. et al.

Infect. Immun. 79:1961-1970(2011) · Mapped (9)

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans.

Leach M.D., Stead D.A., Argo E., MacCallum D.M., Brown A.J.

Mol. Microbiol. 79:1574-1593(2011)

Nitric oxide and nitrosative stress tolerance in yeast.

Tillmann A., Gow N.A., Brown A.J.

Biochem. Soc. Trans. 39:219-223(2011) · Mapped (6)

A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking.

Du X., Kumar J., Ferguson C., Schulz T.A., Ong Y.S., Hong W., Prinz W.A., Parton R.G., Brown A.J., Yang H.

J. Cell Biol. 192:121-135(2011) · UniProtKB (1) · Mapped (15)

Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans.

Leach M.D., Stead D.A., Argo E., Brown A.J.

Mol. Biol. Cell 22:687-702(2011)

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.

Zaibi M.S., Stocker C.J., O'Dowd J., Davies A., Bellahcene M., Cawthorne M.A., Brown A.J., Smith D.M., Arch J.R.

FEBS Lett. 584:2381-2386(2010) · Mapped (2)

A quantitative model for mRNA translation in Saccharomyces cerevisiae.

You T., Coghill G.M., Brown A.J.

Yeast 27:785-800(2010) · Mapped (12)

A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.

Mora-Montes H.M., Bates S., Netea M.G., Castillo L., Brand A., Buurman E.T., Diaz-Jimenez D.F., Jan Kullberg B., Brown A.J., Odds F.C. et al.

J. Biol. Chem. 285:12087-12095(2010) · Mapped (1)

Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans.

Vieira N., Casal M., Johansson B., MacCallum D.M., Brown A.J., Paiva S.

Mol. Microbiol. 75:1337-1354(2010)

Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals.

Nicholls S., Leach M.D., Priest C.L., Brown A.J.

Mol. Microbiol. 74:844-861(2009)

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