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PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli.

Garbett D., Bretscher A.

J. Cell Biol. 198:195-203(2012) · Mapped (4)

Z-line formins promote contractile lattice growth and maintenance in striated muscles of C. elegans.

Mi-Mi L., Votra S., Kemphues K., Bretscher A., Pruyne D.

J. Cell Biol. 198:87-102(2012) · Mapped (3)

EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.

Hokanson D.E., Bretscher A.P.

Mol. Biol. Cell 23:701-715(2012) · Mapped (13)

PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast.

Santiago-Tirado F.H., Legesse-Miller A., Schott D., Bretscher A.

Dev. Cell 20:47-59(2011) · Mapped (15)

The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradation.

LaLonde D.P., Bretscher A.

J. Biol. Chem. 286:4892-4901(2011) · Mapped (6)

The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner.

Garbett D., LaLonde D.P., Bretscher A.

J. Cell Biol. 191:397-413(2010) · Mapped (4)

A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.

LaLonde D.P., Garbett D., Bretscher A.

Mol. Biol. Cell 21:1519-1529(2010) · Mapped (18)

The yeast formin Bnr1p has two localization regions that show spatially and temporally distinct association with septin structures.

Gao L., Liu W., Bretscher A.

Mol. Biol. Cell 21:1253-1262(2010) · Mapped (4)

Polarized growth in budding yeast in the absence of a localized formin.

Gao L., Bretscher A.

Mol. Biol. Cell 20:2540-2548(2009) · Mapped (3)

The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50.

LaLonde D.P., Bretscher A.

Biochemistry 48:2261-2271(2009) · Mapped (6)

A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans.

Bretscher A.J., Busch K.E., de Bono M.

Proc. Natl. Acad. Sci. U.S.A. 105:8044-8049(2008) · UniProtKB (1) · Mapped (13)

Analysis of unregulated formin activity reveals how yeast can balance F-actin assembly between different microfilament-based organizations.

Gao L., Bretscher A.

Mol. Biol. Cell 19:1474-1484(2008) · Mapped (11)

Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.

Ilani T., Khanna C., Zhou M., Veenstra T.D., Bretscher A.

J. Cell Biol. 179:733-746(2007) · Mapped (2)

Expression of the cytoskeleton linker protein ezrin in human cancers.

Bruce B., Khanna G., Ren L., Landberg G., Jirstrom K., Powell C., Borczuk A., Keller E.T., Wojno K.J., Meltzer P. et al.

Clin. Exp. Metastasis 24:69-78(2007) · Mapped (12)

EPI64 regulates microvillar subdomains and structure.

Hanono A., Garbett D., Reczek D., Chambers D.N., Bretscher A.

J. Cell Biol. 175:803-813(2006) · Mapped (7)

A Zn-finger/FH2-domain containing protein, FOZI-1, acts redundantly with CeMyoD to specify striated body wall muscle fates in the Caenorhabditis elegans postembryonic mesoderm.

Amin N.M., Hu K., Pruyne D., Terzic D., Bretscher A., Liu J.

Development 134:19-29(2007) · Mapped (6)

Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domain.

Li Q., Nance M.R., Kulikauskas R., Nyberg K., Fehon R., Karplus P.A., Bretscher A., Tesmer J.J.

J. Mol. Biol. 365:1446-1459(2007) · UniProtKB (1)

Regulated phosphorylation of budding yeast's essential myosin V heavy chain, Myo2p.

Legesse-Miller A., Zhang S., Santiago-Tirado F.H., Van Pelt C.K., Bretscher A.

Mol. Biol. Cell 17:1812-1821(2006) · Mapped (6)

Ezrin mutants affecting dimerization and activation.

Chambers D.N., Bretscher A.

Biochemistry 44:3926-3932(2005) · Mapped (12)

Mechanisms of polarized growth and organelle segregation in yeast.

Pruyne D., Legesse-Miller A., Gao L., Dong Y., Bretscher A.

Annu. Rev. Cell Dev. Biol. 20:559-591(2004) · Mapped (5)

Stable and dynamic axes of polarity use distinct formin isoforms in budding yeast.

Pruyne D., Gao L., Bi E., Bretscher A.

Mol. Biol. Cell 15:4971-4989(2004) · Mapped (3)

The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain.

Finnerty C.M., Chambers D., Ingraffea J., Faber H.R., Karplus P.A., Bretscher A.

J. Cell Sci. 117:1547-1552(2004) · UniProtKB (2)

Global mapping of the yeast genetic interaction network.

Tong A.H., Lesage G., Bader G.D., Ding H., Xu H., Xin X., Young J., Berriz G.F., Brost R.L., Chang M. et al.

Science 303:808-813(2004) · Mapped (943)

Cell biology. Microtubule asymmetry.

Gundersen G.G., Bretscher A.

Science 300:2040-2041(2003) · Mapped (4)

Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast.

Dong Y., Pruyne D., Bretscher A.

J. Cell Biol. 161:1081-1092(2003) · UniProtKB (1) · Mapped (9)

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