| Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2). Lionarons D.A., Boyer J.L., Cai S.Y.
J. Lipid Res. 53:1535-1542(2012) · UniProtKB (2) · Mapped (1) |
| Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Weerachayaphorn J., Mennone A., Soroka C.J., Harry K., Hagey L.R., Kensler T.W., Boyer J.L.
Am. J. Physiol. Gastrointest. Liver Physiol. 302:G925-36(2012) · Mapped (2) |
| A C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis. Lam P., Xu S., Soroka C.J., Boyer J.L.
Hepatology 55:1901-1911(2012) · Mapped (5) |
| Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-signaling pathway. Chai J., He Y., Cai S.Y., Jiang Z., Wang H., Li Q., Chen L., Peng Z., He X., Wu X. et al.
Hepatology 55:1485-1494(2012) · Mapped (13) |
| P2Y(2) receptor activation decreases blood pressure and increases renal Na⁺ excretion. Rieg T., Gerasimova M., Boyer J.L., Insel P.A., Vallon V.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 301:R510-8(2011) · Mapped (6) |
| NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function. Li M., Wang W., Soroka C.J., Mennone A., Harry K., Weinman E.J., Boyer J.L.
J. Biol. Chem. 285:19299-19307(2010) · Mapped (13) |
| Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Xu S., Weerachayaphorn J., Cai S.Y., Soroka C.J., Boyer J.L.
Am. J. Physiol. Gastrointest. Liver Physiol. 299:G126-35(2010) · Mapped (16) |
| Nuclear factor erythroid 2-related factor 2 is a positive regulator of human bile salt export pump expression. Weerachayaphorn J., Cai S.Y., Soroka C.J., Boyer J.L.
Hepatology 50:1588-1596(2009) · Mapped (12) |
| ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained. Cai S.Y., Gautam S., Nguyen T., Soroka C.J., Rahner C., Boyer J.L.
Gastroenterology 136:1060-1069(2009) · Mapped (8) |
| N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta. Soroka C.J., Xu S., Mennone A., Lam P., Boyer J.L.
BMC Cell Biol. 9:57-57(2008) · Mapped (4) |
| Nucleotide P2Y1 receptor regulates EGF receptor mitogenic signaling and expression in epithelial cells. Buvinic S., Bravo-Zehnder M., Boyer J.L., Huidobro-Toro J.P., Gonzalez A.
J. Cell. Sci. 120:4289-4301(2007) · Mapped (20) |
| Membrane trafficking of the human organic anion-transporting polypeptide C (hOATPC). Sun A.Q., Ponamgi V.M., Boyer J.L., Suchy F.J.
Pharm. Res. 25:463-474(2008) · Mapped (5) |
| The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. Cai S.Y., Xiong L., Wray C.G., Ballatori N., Boyer J.L.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 293:R1400-9(2007) · UniProtKB (1) |
| Nuclear receptors RXRalpha:RARalpha are repressors for human MRP3 expression. Chen W., Cai S.Y., Xu S., Denson L.A., Soroka C.J., Boyer J.L.
Am. J. Physiol. Gastrointest. Liver Physiol. 292:G1221-7(2007) · Mapped (7) |
| Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. Wang W., Soroka C.J., Mennone A., Rahner C., Harry K., Pypaert M., Boyer J.L.
Gastroenterology 131:878-884(2006) · Mapped (1) |
| Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis. Mennone A., Soroka C.J., Cai S.Y., Harry K., Adachi M., Hagey L., Schuetz J.D., Boyer J.L.
Hepatology 43:1013-1021(2006) · UniProtKB (2) |
| Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. Boyer J.L., Trauner M., Mennone A., Soroka C.J., Cai S.Y., Moustafa T., Zollner G., Lee J.Y., Ballatori N.
Am. J. Physiol. Gastrointest. Liver Physiol. 290:G1124-30(2006) · Mapped (8) |
| OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Ballatori N., Christian W.V., Lee J.Y., Dawson P.A., Soroka C.J., Boyer J.L., Madejczyk M.S., Li N.
Hepatology 42:1270-1279(2005) · UniProtKB (3) · Mapped (2) |
| Regulation of P2Y1 receptor-mediated signaling by the ectonucleoside triphosphate diphosphohydrolase isozymes NTPDase1 and NTPDase2. Alvarado-Castillo C., Harden T.K., Boyer J.L.
Mol. Pharmacol. 67:114-122(2005) · Mapped (6) |
| Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis. Denk G.U., Soroka C.J., Mennone A., Koepsell H., Beuers U., Boyer J.L.
Hepatology 39:1382-1389(2004) · UniProtKB (1) |
| Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat. Denk G.U., Soroka C.J., Takeyama Y., Chen W.S., Schuetz J.D., Boyer J.L.
J. Hepatol. 40:585-591(2004) · Mapped (2) |
| Requirement of Cys399 for processing of the human ecto-ATPase (NTPDase2) and its implications for determination of the activities of splice variants of the enzyme. Mateo J., Kreda S., Henry C.E., Harden T.K., Boyer J.L.
J. Biol. Chem. 278:39960-39968(2003) · Mapped (2) |
| Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. Bohan A., Chen W.S., Denson L.A., Held M.A., Boyer J.L.
J. Biol. Chem. 278:36688-36698(2003) · Mapped (16) |
| Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta. Seward D.J., Koh A.S., Boyer J.L., Ballatori N.
J. Biol. Chem. 278:27473-27482(2003) · UniProtKB (3) · Mapped (3) |
| Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Abbracchio M.P., Boeynaems J.M., Barnard E.A., Boyer J.L., Kennedy C., Miras-Portugal M.T., King B.F., Gachet C., Jacobson K.A., Weisman G.A. et al.
Trends Pharmacol. Sci. 24:52-55(2003) · Mapped (2) |
